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Under simple- and choice-RT conditions, the biceps brachii muscle was examined in 8 healthy male subjects to determine how the temporal and spatial characteristics of elbow flexion and forearm supination differed at the initial phase of EMG activity and whether preparation or the presence of response uncertainty influenced the EMG outputs of the two movements. In the simple-RT condition, RT of supination was significantly faster than that of flexion but EMG activity of supination was less than that of flexion. In contrast, in the choice-RT condition, RT of flexion was significantly faster than that of supination but EMG activity of flexion was significantly reduced compared to supination. These findings indicate that advanced preparation or motor set facilitates the differentiation of RTs and EMG activities of the response movements and that response uncertainty causes a significant change in the temporal and spatial specificity of both elbow flexion and forearm supination.  相似文献   
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Cognitive impairment in schizophrenia and other psychiatric disorders is a challenge to be overcome in order to maintain patients' quality of life and social function. The neurological pathogenesis of cognitive impairment requires further elucidation. In general, the hippocampus interacts between the cortical and subcortical areas for information processing and consolidation and has an important role in memory. We examined the relationship between structural connectivity of the hippocampus and cortical/subcortical areas and cognitive impairment in schizophrenia, major depressive disorder and bipolar disorder. Subjects comprised 21 healthy controls, 19 patients with schizophrenia, 20 patients with bipolar disorder and 18 patients with major depressive disorder. Diffusion-weighted tensor images data were processed using ProbtrackX2 to calculate the structural connectivity between the hippocampus and cortical/subcortical areas. Cognitive function was assessed using the Brief Assessment of Cognition in schizophrenia composite score. Hippocampal structural connectivity index was significantly correlated with composite score in the schizophrenia group but not in the healthy control, major depressive disorder or bipolar disorder groups. There were no statistically significant differences in hippocampal structural connectivity index between the four groups. Structural connectivity between the hippocampus and cortical/subcortical areas is suggested to be a pathophysiological mechanism of comprehensive cognitive impairment in schizophrenia.  相似文献   
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The essay examines the argument advanced by E.D. Hirsch, Jr., for instituting ‘cultural literacy’ as a fundamental priority of schools. A number of confusions and equivocations in Hirsch's reasoning are identified, and the propensity of his project to indoctrinate is exposed. Among the features of Hirsch's argument shown to be troubling are his shifting construal of ‘language’, his inconsistency about the requirements of cultural literacy, and his uncritical relation to traditional images of the American past and present. The upshot is to raise the question why Hirsch's project has elicited wide support and praise.  相似文献   
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How can we explain that an assertion on something perceived can be understood in the same manner by somebody who cannot perceive that scene? This problem bases the interest in computational linguistics in how listener modeling could possibly be harmonized with reference semantics. Mental images substituting real perception appear as a way out. The architecture of the listener model has to be adapted to the creation and use of such pictorial data structures. Furthermore, the relation between the latter and a verbal (i. e., propositional) representation must be understood. The resulting architecture of a listener model with reference semantics can be employed to solve communicational problems from three general classes in a better way, as is demonstrated by an example implementation.  相似文献   
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The accreditation standards outlined in the article are used by the International Association of Counseling Services, Inc., as the basis for the formal accreditation of college and university counseling programs throughout the United States and Canada. They reflect the program elements and practice standards that are deemed essential in a counseling center that provides high-quality services to students.  相似文献   
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The discrimination learning of the /r/ and /l/ sounds in a single 1-h session by Japanese college students who had received little or no English conversation training was examined. About half of the subjects exhibited significant improvement after this brief amount of training. A three-state Markov model with the unconditioned, intermediate, and conditioned states was applied as a first approximation of the learning of the liquid pairs, learning which is characterized as two-stage all-or-none conditioning. Also found in the study was a significant correlation between the ability to perceive the liquids and the ability to read English as assessed by a cloze procedure. This correlation is interreted in light of general theory on phoneme awareness.  相似文献   
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