Differential involvement of the central amygdala in appetitive versus aversive learning

Understanding the function of the distinct amygdaloid nuclei in learning comprises a major challenge. In the two studies described herein, we used c-Fos immunolabeling to compare the engagement of various nuclei of the amygdala in appetitive and aversive instrumental training procedures. In the first experiment, rats that had already acquired a bar-pressing response to a partial food reinforcement were further trained to learn that an acoustic stimulus signaled either continuous food reinforcement (appetitive training) or a footshock (aversive training). The first training session of the presentation of the acoustic stimulus resulted in significant increases of c-Fos immunolabeling throughout the amygdala; however, the pattern of activation of the nuclei of the amygdala differed according to the valence of motivation. The medial part of the central amygdala (CE) responded, surprisingly, to the appetitive conditioning selectively. The second experiment was designed to extend the aversive versus appetitive conditioning to mice, trained either for place preference or place avoidance in an automated learning system (INTELLICAGE). Again, much more intense c-Fos expression was observed in the medial part of the CE after the appetitive training as compared to the aversive training. These data, obtained in two species and by means of novel experimental approaches balancing appetitive versus aversive conditioning, support the hypothesis that the central nucleus of the amygdala is particularly involved in appetitively motivated learning processes.     

A preliminary psychometric evaluation of the Hospital Anxiety and Depression Scale (HADS) in 963 people living with a spinal cord injury

This study aimed to evaluate the preliminary psychometric properties of the Hospital Anxiety and Depression Scale (HADS) in a community sample of adults living with a spinal cord injury (SCI). A cross-sectional design was used with 963 people living in the community with an SCI. Participants were recruited via three spinal centres in the United Kingdom. They completed the HADS and the Life Satisfaction Questionnaire. Psychometric analyses were conducted for the whole sample, by gender and level of injury. The HADS demonstrated good internal consistency, with promising content validity. Two factors, approximating to anxiety and depression were extracted via factor analysis for the whole sample, by gender and level of injury. In line with existing literature, females scored significantly higher than males on the anxiety subscale. Item 7 ("I can sit at ease and feel relaxed") was found to be a complex item, with a potentially different meaning within this population. This study presents preliminary findings, which support the psychometric integrity of the HADS within an outpatient population with SCI. Items that included potential somatic components revealed a more complex factor loading profile. Recommendations are made to further investigate this measure with amendments to such items, incorporating inpatients and independent measures of anxiety and depression to address validity directly.     

A cognitive and an affective dimension of alexithymia in six languages and seven populations

The Dutch Bermond–Vorst Alexithymia Questionnaire (BVAQ) is translated into various languages. The aim of this research was to establish the factor structure of subscales on seven cultural groups. The BVAQ consists of five subscales of eight items each: Emotionalising, Fantasising, Analysing, Identifying, and Verbalising emotions. The BVAQ was administered to a group of Dutch students (n=375), a group of English students (n=175), a group of Australian students, university employees and visitors (n=216), a group of French speaking Belgian students (n=175), a group of Italian people (n=791; a mix of various clinical groups), a group of Polish people (n=427; also a mix of various clinical groups) and a group of Russian people (n=141; general population). The hypothesised two-factor structure of an affective alexithymia dimension (Emotionalising, Fantasising) and a cognitive alexithymia dimension (Insight and Verbalising), with “Analysing emotions” loading on both factors, was clearly supported by confirmatory factor analyses (CFA). Both orthogonal and oblique principal components analyses (PCA), without restriction concerning the number of factors, provided the same two-factor solution in all groups explaining between 55% and 64% of the variance. Oblique rotation further demonstrated that the correlations between these two factors were low in all populations. The combined CFA and PCA results, therefore, indicated that a model with two independent factors has to be preferred over the model assuming two correlated factors.     

Is God His Essence? The Logical Structure of Aquinas’ Proofs for this Claim

In this article I consider whether Aquinas’ arguments for the claim that God is His essence are conclusive, and what was his purpose of upholding this thesis. I show his proofs from Summa Theologiae and Summa Contra Gentiles to be problematic and argue that the defense of Aquinas’ views on that matter suggested by certain remarks of P. T. Geach is flawed.     

The Nencki Affective Picture System (NAPS): Introduction to a novel,standardized, wide-range,high-quality,realistic picture database

Selecting appropriate stimuli to induce emotional states is essential in affective research. Only a few standardized affective stimulus databases have been created for auditory, language, and visual materials. Numerous studies have extensively employed these databases using both behavioral and neuroimaging methods. However, some limitations of the existing databases have recently been reported, including limited numbers of stimuli in specific categories or poor picture quality of the visual stimuli. In the present article, we introduce the Nencki Affective Picture System (NAPS), which consists of 1,356 realistic, high-quality photographs that are divided into five categories (people, faces, animals, objects, and landscapes). Affective ratings were collected from 204 mostly European participants. The pictures were rated according to the valence, arousal, and approach–avoidance dimensions using computerized bipolar semantic slider scales. Normative ratings for the categories are presented for each dimension. Validation of the ratings was obtained by comparing them to ratings generated using the Self-Assessment Manikin and the International Affective Picture System. In addition, the physical properties of the photographs are reported, including luminance, contrast, and entropy. The new database, with accompanying ratings and image parameters, allows researchers to select a variety of visual stimulus materials specific to their experimental questions of interest. The NAPS system is freely accessible to the scientific community for noncommercial use by request at http://naps.nencki.gov.pl.     

Quality of Life and Optimism in Patients with Morphea

Despite extensive knowledge about quality of life of people suffering from dermatological diseases, data on patients with morphea are scarce. The aim of our study was to compare the quality of life of healthy controls and morphea patients, as well as to determine the correlation of this variable with the level of dispositional optimism. The study included 47 patients with morphea and 47 healthy controls, matched for gender and age. Cantril’s Ladder and Life Orientation Test-Revised were used to assess the levels of life satisfaction and dispositional optimism, respectively. LoSSI was used for the objective assessment. The anticipated level of life quality and the level of dispositional optimism were statistically significantly lower in morphea patients (p?=?0.032 and p?=?0.014, respectively) when compared to controls. There were no differences in the assessment of current (p?=?0.168) and past (p?=?0.318) levels of life quality. Also, we proved that type of morphea did not differentiate the current (p?=?0.175), past (p?=?0.620) and future (p?=?0.356) assessment of the quality of life. In the group of morphea patients there was a statistically significant correlation between the level of dispositional optimism and current (p?=?0.002, r?=?0.43), as well as anticipated (p?r?=?0.57) levels of life quality. Current level of life quality of healthy controls and morphea patients is comparable, whereas the latter anticipate their future life situation to be significantly worse than the former. Higher level of life satisfaction correlates with higher level of optimism.     

The chameleon effect,the temporal aspects of mimicry and their impact on service measurement

BackgroundIn an experiment conducted in a natural setting, we test the link between mimicry, the amount of time during which the mimicry behavior takes place, and its impact on service quality.MethodsCable TV clients (n = 120) were randomly assigned to six experimental conditions (2 mimicry conditions: verbal mimicry vs. no mimicry x 3 interaction time: 5 vs. 10 vs. 15 minutes). Perceived service quality served as the dependent measurement.ResultsA main effect of mimicry was found on service quality: a cable TV representative was perceived more favorably when he mimicked the customer. Importantly, it was shown that even small portions of mimicry are beneficial, meaning that practitioners do not have to mimic someone for a long time to achieve benefits.ConclusionThe paper shows new benefits for the mimicker: more positive judgments by the mimickee regarding the impact on several different levels of service quality.