Memory for individual items is related to nonreinforced preference change

It is commonly assumed that memories contribute to value-based decisions. Nevertheless, most theories of value-based decision-making do not account for memory influences on choice. Recently, new interest has emerged in the interactions between these two fundamental processes, mainly using reinforcement-based paradigms. Here, we aimed to study the role memory processes play in preference change following the nonreinforced cue-approach training (CAT) paradigm. In CAT, the mere association of cued items with a speeded motor response influences choices. Previous studies with this paradigm showed that a single training session induces a long-lasting effect of enhanced preferences for high-value trained stimuli, that is maintained for several months. We hypothesized that CAT increases memory of trained items, leading to enhanced accessibility of their positive associative memories and in turn to preference changes. In two preregistered experiments, we found evidence that memory is enhanced for trained items and that better memory is correlated with enhanced preferences at the individual item level, both immediately and 1 mo following CAT. Our findings suggest that memory plays a central role in value-based decision-making following CAT, even in the absence of external reinforcements. These findings contribute to new theories relating memory and value-based decision-making and set the groundwork for the implementation of novel nonreinforced behavioral interventions that lead to long-lasting behavioral change.

Value-based decision-making and memory are both extensively studied processes in cognitive psychology and cognitive neuroscience (Fellows 2017). Most theories of value-based decision-making have focused on processes related to the incremental learning of value following external reinforcement, but have not explicitly addressed the role of memory per se. Thus, fundamental questions remain regarding interactions between memory and value-based decisions, which have been gaining attention in recent years.Several recent empirical studies have demonstrated interactions between episodic memory and value-based decision-making. For example, memory for past events has been shown to bias value-based decisions (Duncan and Shohamy 2016), differently for choices of novel versus choices of familiar options (Duncan et al. 2019), and choice behavior and fMRI signals during value-based decision-making were better explained by episodic memory for individual past choices than by a standard reinforcement learning model (Bornstein et al. 2017). Another study has found that during sampling of episodic memories of previous choices, the retrieved context influenced present choices, deviating from the predictions of standard reinforcement learning models (Bornstein and Norman 2017). Other studies have demonstrated that the long time known effect of choices on future preferences is related to memory processes (Chammat et al. 2017; DuBrow et al. 2019; Luettgau et al. 2020). At the neural level, the ventromedial prefrontal cortex (vmPFC) and the hippocampus both have been shown to play a role in memory processes and value-based decisions (Weilbächer and Gluth 2017) and recent studies have been further emphasizing that the hippocampus bridges between past experience and future decisions (Bakkour et al. 2019; Biderman et al. 2020).All these studies, and many others, highlighted the interaction between memory and value-based decision-making involving external reinforcements. However, everyday life involves decisions and associations that are not directly reinforced. Thus, it remains unclear whether memory plays a general role in value-based decision-making even without external reinforcements.To better understand the role of memory processes in shaping preferences independently of external reinforcements, we used a novel behavioral change paradigm, named cue-approach training (CAT). In this paradigm, associating images of items with a neutral cue and a speeded motor response results in a consistent preference enhancement without external reinforcement, which is maintained for months (Schonberg et al. 2014; Bakkour et al. 2018; Salomon et al. 2018, 2019; Botvinik-Nezer et al. 2020). During CAT, images of items are consistently paired with a neutral cue and a speeded motor response (“Go items”), while other items are presented without the cue or the response (“NoGo items”). One training session with several presentations of all items leads to long-lasting preference changes, measured as the likelihood of choosing Go over NoGo items that had similar initial subjective values (Schonberg et al. 2014). Results from over 30 samples with this paradigm have demonstrated a replicable effect on various types of stimuli, including snack food items, fruits and vegetables, unfamiliar faces, fractal art images, and positive affective images (Bakkour et al. 2016, 2017; Veling et al. 2017; Zoltak et al. 2017; Bakkour et al. 2018; Salomon et al. 2018, 2019; Botvinik-Nezer et al. 2020), revealing the potential of the CAT paradigm as an experimental platform for value-based decision-making without external reinforcements (Schonberg and Katz 2020).The underlying mechanisms of the change of preferences following CAT are not yet fully understood (Schonberg et al. 2014; Bakkour et al. 2017; Salomon et al. 2019; Botvinik-Nezer et al. 2020; Schonberg and Katz 2020). The long-lasting nature of the effect, which has been shown to last for up to 6 mo following a single training session (Schonberg et al. 2014; Salomon et al. 2018, 2019; Botvinik-Nezer et al. 2020), raises the hypothesis that memory processes are involved in its maintenance. Furthermore, previous studies have found enhanced memory for Go compared with NoGo items with other types of Go–NoGo tasks (Chiu and Egner 2015a,b; Yebra et al. 2019) and for items for which participants have a sense of agency (Murty et al. 2015). One recent study provided preliminary evidence suggesting that memory is involved in preference change following a similar nonreinforced Go/NoGo training task (Chen et al. 2021).We hypothesized that CAT enhances memory of Go items, which in turn leads to preferring these items over NoGo items. Previous neuroimaging findings with CAT that suggested possible interactions between hippocampal fMRI activity and subsequent preferences 1 mo following CAT, provide additional evidence in support of this hypothesis (Botvinik-Nezer et al. 2020). Therefore, here we set out to test the role memory processes play in the behavioral change of preferences following CAT, in the short and in the long term.We propose an underlying mechanism for the CAT effect, in which preference change following CAT results from a boost in memory encoding of positive Go items, which in itself is a consequence of enhanced perceptual processing of Go items (Schonberg et al. 2014; Botvinik-Nezer et al. 2020). We hypothesize that the enhanced encoding of Go items, as well as the greater perceptual activation in response to them, increases accessibility of attributes and associations of these specific Go items (Anderson 1983; Bhatia 2013). Furthermore, we hypothesized that preference changes, reflected in the binary choice phase, are due to the enhanced accessibility of memory associations of the Go items, which tips the scales in favor of the Go items when the associations are positive.In order to test memory for individual items, in the current work we introduced a memory recognition task following CAT. In two independent preregistered experiments and one pilot experiment, memory was evaluated following a long (16 repetitions) or short (a single exposure) CAT training session, before the probe phase that evaluated post-training preferences. We then tested our predictions that (1) memory will be stronger for Go compared with NoGo items following CAT (more accurate and faster responses in the recognition task) and (2) that memory will be related to choices (better remembered Go items will be chosen over worse remembered NoGo items). Since the link between better memory and enhanced choices is hypothesized to be related to positive associated memories, we tested the relationship between memory and choices separately for choices between low-value and choices between high-value items. These hypotheses were tested both in the short term (immediately or a few days after CAT) and in a 1-mo follow-up.     

Establishing Arbitrary Stimulus Classes via Identity-matching Training and Non-reinforced Matching with Complex Stimuli

The present study investigated whether training on an identity match-to-sample task followed by non-reinforced matching probes with complex stimuli leads to the emergence of multiple arbitrary matching performances and arbitrary stimulus classes in preschool children. In Experiment 1, eight subjects were trained on a colour-matching task (A-A). Then they received tests with complex AB and AC colour-form stimuli (AB-A, B-AB; AC-A, C-AC). These tasks were designed to help subjects respond to both elements of each complex stimulus. Subsequent B-A, C-A, A-B, A-C, B-C, and C-B tests revealed that all subjects had acquired class-consistent colour-form and form-form relations. Experiment 2 examined whether these results could be replicated when subjects were encouraged to respond to the colour elements of some (AB) complex stimuli and to the form elements of other (AC) stimuli. The procedures were the same as in Experiment 1 except that during the first test only A-AB and C-AC tasks were used. Six of eight subjects demonstrated all tested relations.     

Emergent Simple Discrimination via Transfer from Differentially Reinforced S+ Stimuli: A Further Test of the Stimulus-Response Interaction Model

This study examined emergent form discrimination through contiguity of the forms (B stimuli) with colours (A stimuli) associated with different magnitudes of reinforcement. In Experiment 1, children were trained on two colour discriminations. In both, the colour stimuli had the same form: A1B1/A2B1 and A3B1/A2B1. Responding to A1/B1 was followed by three units of reinforcement, to A3B1 by one unit of reinforcement, and to A2B1 by no reinforcement. There followed five tests in which stimuli were presented without programmed consequences. These assessed: (1) the maintenance of accurate performance on the training tasks; (2) S+ preference (A1B1/A3B1); (3) stimulus generalization (A1B2/A2B3, A3B4/A2B5); (4) S+ preference again (A1B6/A3B6); and (5) transfer from the S+ colours to the forms (A4B2/A4B4). On the final test, seven of the eight subjects selected A4B2. Experiment 2 demonstrated that a preference for A4B2 also occurred when the S+ preference tests were omitted. This preference was also found when the total amounts of reinforcement associated with the S+ colours (A1 and A3) were the same (Experiment 3). These findings: (a) indicate that children can acquire new discriminations under non-reinforced conditions through contiguity with differentially reinforced S+ stimuli; (b) support the Stimulus-Response Interaction model (Smeets, 1993) for specifying transfer.     

Stepfamilies Doing Family: A Meta‐Ethnography

The present review examines how stepfamily members without a shared history co‐construct a shared family identity and what family processes are relevant in this stepfamily formation. Three databases (Web of Science, PsycInfo, and ProQuest) were systematically searched, resulting in 20 included qualitative studies. The meta‐ethnography approach of Noblit and Hare allowed synthesizing these qualitative studies and constructing a comprehensive framework of stepfamilies doing family. Three interdependent family tasks were identified: (a) honoring the past, (b) marking the present, and (c) investing in the future. Stepfamily members’ experiences of these family tasks are strongly affected by the dominant societal perspectives and characterized by an underlying dialectical tension between wanting to be like a first‐time family and feeling the differences in their family structure at the same time. These findings clearly demonstrate the family work that all stepfamily members undertake and provide a broader context for interpreting stepfamilies’ co‐construction of a new family identity.     

Adjunctive mirror exposure for eating disorders: A randomized controlled pilot study

Mirror exposure therapy has proven efficacious in improving body image among individuals with shape/weight concerns and eating disorders. No randomized controlled trials have examined the effect of mirror exposure in a healthy-weight clinical sample of eating disordered individuals. The purpose of the current study was to test the efficacy of a five-session acceptance based mirror exposure therapy (A-MET) versus a non directive body image therapy (ND) control as an adjunctive treatment to outpatient eating disorder treatment. Thirty-three males and females aged 14–65 with a body mass index of 18.5–29.9 were randomized to five sessions of A-MET or ND with a 1-month follow-up. Results indicated large to moderate effect size differences for efficacy of A-MET across measures of body checking, body image dissatisfaction, and eating disorder symptoms (d = ?0.38 to ?1.61) at end of treatment and follow-up. Baseline measures of social comparison and history of appearance-related teasing were predictive of treatment response. There were also differential effects of treatment on participants' perceived homework quality, but no differences in therapeutic alliance. Results suggest that A-MET is a promising adjunctive treatment for residual body image disturbance among normal and overweight individuals undergoing treatment for an eating disorder. Future research and clinical implications are discussed.     

Listening comprehension and working memory are impaired in attention-deficit hyperactivity disorder irrespective of language impairment

This study investigated listening comprehension and working memory abilities in children with attention-deficit hyperactivity disorder (ADHD), presenting with and without language impairments (LI). A 4-group design classified a community sample (n = 77) of boys aged 9–12 into ADHD, ADHD + LI, LI, and Normal groups. Children completed tests of basic language and cognitive skills, verbal and spatial working memory, and passage-level listening comprehension. Multivariate analyses and post hoc comparisons indicated that ADHD children who did not have co-occurring LI comprehended factual information from spoken passages as well as normal children, but were poorer at comprehending inferences and monitoring comprehension of instructions. ADHD children did not differ from normal children in verbal span, but showed significantly poorer verbal working memory, spatial span, and spatial working memory. The ADHD + LI and LI groups were most impaired in listening comprehension and working memory performance, but did not differ from each other. Listening comprehension skills were significantly correlated with both verbal and spatial working memory, and parent–teacher ratings of inattention and hyperactivity/impulsivity. Findings that children with ADHD but no LI showed subtle higher-level listening comprehension deficits have implications for both current diagnostic practices and conceptualizations of ADHD.     

Disgusting clusters: trypophobia as an overgeneralised disease avoidance response

Individuals with trypophobia have an aversion towards clusters of roughly circular shapes, such as those on a sponge or the bubbles on a cup of coffee. It is unclear why the condition exists, given the harmless nature of typical eliciting stimuli. We suggest that aversion to clusters is an evolutionarily prepared response towards a class of stimuli that resemble cues to the presence of parasites and infectious disease. Trypophobia may be an exaggerated and overgeneralised version of this normally adaptive response. Consistent with this explanation, individuals with trypophobia, as well as comparison individuals, reported aversion towards disease-relevant cluster stimuli, but only the trypophobic group reported aversion towards objectively harmless cluster stimuli that had no relevance to disease. For both groups the level of aversion reported was predicted uniquely by a measure of disgust sensitivity. Scaled emotion ratings and open-ended responses revealed that the aversive response was predominantly based on the disease avoidance emotion, disgust. Many open-ended responses also described skin sensations (e.g. skin itching or skin crawling). These findings support the proposal that individuals with trypophobia primarily perceive cluster stimuli as cues to ectoparasites and skin-transmitted pathogens.     

Stress during puberty boosts metabolic activation associated with fear-extinction learning in hippocampus, basal amygdala and cingulate cortex

Adolescence is characterized by major developmental changes that may render the individual vulnerable to stress and the development of psychopathologies in a sex-specific manner. Earlier we reported lower anxiety-like behavior and higher risk-taking and novelty seeking in rats previously exposed to peri-pubertal stress. Here we studied whether peri-pubertal stress affected the acquisition and extinction of fear memories and/or the associated functional engagement of various brain regions, as assessed with 2-deoxyglucose. We showed that while peri-pubertal stress reduced freezing during the acquisition of fear memories (training) in both sexes, it had a sex-specific effect on extinction of these memories. Moreover hippocampus, basal amygdala and cingulate and motor cortices showed higher metabolic rates during extinction in rats exposed to peri-pubertal stress. Interestingly, activation of the infralimbic cortex was negatively correlated with freezing during extinction only in control males, while only males stressed during puberty showed a significant correlation between behavior during extinction and metabolic activation of hippocampus, amygdala and paraventricular nucleus. No correlations between brain activation and behavior during extinction were observed in females (control or stress). These results indicate that exposure to peri-pubertal stress affects behavior and brain metabolism when the individual is exposed to an additional stressful challenge. Some of these effects are sex-specific.     

Do humans prefer to see their grasping points?

ABSTRACT To grasp an object the digits need to be placed at suitable positions on its surface. The selection of such grasping points depends on several factors. Here the authors examined whether being able to see 1 of the selected grasping points is such a factor. Subjects grasped large cylinders or oriented blocks that would normally be grasped with the thumb continuously visible and the final part of the index finger's trajectory occluded by the object in question. An opaque screen that hid the thumb's usual grasping point was used to examine whether individuals would choose a grip that was oriented differently to maintain vision of the thumb's grasping point. A transparent screen was used as a control. Occluding the thumb's grasping point made subjects move more carefully (adopting a larger grip aperture) and choose a slightly different grip orientation. However, the change in grip orientation was much too small to keep the thumb visible. The authors conclude that humans do not particularly aim for visible grasping points.     

Development of adolescents' peer crowd identification in relation to changes in problem behaviors

This 5-wave longitudinal study, which included 1,313 Dutch adolescents, examined the development of peer crowd identification in relation to changes in problem behaviors. Adolescents from 2 age cohorts annually reported their identification with 7 peer crowds and their levels of internalizing and externalizing problem behaviors. Univariate latent growth curve analyses revealed declines (i.e., "Hip Hoppers" and "Metal Heads") or declines followed by stabilization (i.e., "Nonconformists") in identification with nonconventional crowds and increases (i.e., "Elites" and "Brains") or declines followed by stabilization (i.e., "Normals" and "Jocks") in identification with conventional crowds. Multivariate latent growth curve analyses indicated that stronger and more persistent identifications with nonconventional crowds were generally associated with more problem behaviors throughout adolescence. In contrast, stronger and more persistent identifications with conventional crowds were generally associated with fewer problem behaviors throughout adolescence with the notable exception of Brains, who showed a mixed pattern. Though characterized by fewer externalizing problems, this group did report more anxiety problems. These findings and their implications are discussed.