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31.
Working and long-term memory deficits in schizophrenia: is there a common prefrontal mechanism? 总被引:3,自引:0,他引:3
This study tested the hypothesis that dorsolateral prefrontal cortex deficits contribute to both working memory and long-term memory disturbances in schizophrenia. It also examined whether such deficits were more severe for verbal than nonverbal stimuli. Functional magnetic resonance imaging was used to assess cortical activation during performance of verbal and nonverbal versions of a working memory task and both encoding and recognition tasks in 38 individuals with schizophrenia and 48 healthy controls. Performance of both working memory and long-term memory tasks revealed disturbed dorsolateral prefrontal cortex activation in schizophrenia, although medial temporal deficits were also present. Some evidence was found for more severe cognitive and functional deficits with verbal than nonverbal stimuli, although these results were mixed. 相似文献
32.
The purpose of this study was to determine the effects of teacher feedback delivered via a public address system on the off-task behavior of elementary-school physical education students. A multiple baseline design across three classes was used in this investigation. Results indicated a consistent decline in off-task behavior when the public address feedback system was used. 相似文献
33.
Response time studies of acquired language disorders are plagued by tremendous variability in patients' response times. In this brief report we demonstrate how variability itself may provide informative data. Lexical decision response times, generated by nine patients, illustrate how within-patient variability may estimate stability in cognitive dynamics. 相似文献
34.
Buchanan A Califano A Kahn J McPherson E Robertson J Brody B 《Kennedy Institute of Ethics journal》2002,12(1):1-15
Pharmacogenetics offers the prospect of an era of safer and more effective drugs, as well as more individualized use of drug therapies. Before the benefits of pharmacogenetics can be realized, the ethical issues that arise in research and clinical application of pharmacogenetic technologies must be addressed. The ethical issues raised by pharmacogenetics can be addressed under six headings: (1) regulatory oversight, (2) confidentiality and privacy, (3) informed consent, (4) availability of drugs, (5) access, and (6) clinicians' changing responsibilities in the era of pharmacogenetic medicine. We analyze each of these categories of ethical issues and provide policy approaches for addressing them. 相似文献
35.
Buchanan RD 《History of psychology》2002,5(3):284-309
Psychological tests, especially the Minnesota Multiphasic Personality Inventory, became the center of public controversy and Congressional scrutiny during the 1960s. This unwanted attention actually helped American psychologists more than they imagined. Assisted by those on Capital Hill, psychologists were able to defend their science in a manner that avoided imposed forms of public accountability. Social questions were reformulated as technical problems. The need to adjust intelligence and aptitude tests reinforced psychologists' control over them. Conversely, personality tests were not made more transparent and nonintrusive, unless psychologists thought these changes were scientifically necessary. This episode prompted tighter regulation of test use and demonstrated that traditional forms of testing were far too important to popularize and "give away". 相似文献
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37.
Deep dyslexia is diagnosed when brain-injured, previously literate adults make reading errors that include hallmark semantic paralexias (e.g., reading HEART as BLOOD) and are also impaired at reading nonwords (e.g., FRIP). The diversity of these symptoms have led most researchers to conclude that there are multiple sources of impairment in this syndrome and that one of the most critical is a failure to process phonological information at a sublexical level. The patient (SD) reported in this study fits the deep dyslexia profile to the extent that she makes several semantically related reading errors. She also shows the classic frequency and image ability effects of the syndrome. However, as we report, she does read some nonwords correctly and she shows a strong advantage for naming when phonemic cues are presented. We discuss the performance of SD, on these preliminary tasks, in terms of a phonological selection impairment. 相似文献
38.
A distinction between forms of social identity formation in small interactive groups is investigated. In groups in which a common identity is available or given, norms for individual behavior may be deduced from group properties (deductive identity). In groups in which interpersonal relations are central, a group identity may also be induced from individual group members' contributions, making individuality and individual distinctiveness a defining feature of the group (inductive identity). Two studies examined the prediction that depersonalization produced by anonymity has opposite effects for groups in which social identity has been induced or deduced. Results confirmed the prediction that depersonalization increases social influence in groups whose identity was more deductive. In contrast, depersonalization decreases social influence in inductive identity groups. Implications for the role of social identity in small groups are discussed. ((c) 2005 APA, all rights reserved). 相似文献
39.
This study examined the dimensional structure of Tomás-Sábado and Gómez-Benito's Death Anxiety Inventory and Templer, et al.'s Death Depression Scale-Revised. The responses of 244 Spanish nurses to the Spanish forms of both scales were evaluated by means of a principal axis factor analysis with direct Oblimin rotation. Five significant factors were identified: Internally Generated Death Anxiety, Death Depression, Externally Generated Death Anxiety, Death Threat, and Death Sadness, accounting for 51.6% of the variance. The distribution of the factor loadings for the items of both scales on the five factors supported the discriminant validity of the constructs specific to each of the scales and justified their use in evaluating death anxiety and death depression independently. 相似文献
40.