Neuroethics,confidentiality, and a cultural imperative in early onset Alzheimer disease: a case study with a First Nation population

The meaningful consideration of cultural practices, values and beliefs is a necessary component in the effective translation of advancements in neuroscience to clinical practice and public discourse. Society’s immense investment in biomedical science and technology, in conjunction with an increasingly diverse socio-cultural landscape, necessitates the study of how potential discoveries in neurodegenerative diseases such as Alzheimer disease are perceived and utilized across cultures. Building on the work of neuroscientists, ethicists and philosophers, we argue that the growing field of neuroethics provides a pragmatic and constructive pathway to guide advancements in neuroscience in a manner that is culturally nuanced and relevant. Here we review a case study of one issue in culturally oriented neuroscience research where it is evident that traditional research ethics must be broadened and the values and needs of diverse populations considered for meaningful and relevant research practices. A global approach to neuroethics has the potential to furnish critical engagement with cultural considerations of advancements in neuroscience.     

The place of words and numbers in psychiatric research

In recent decades, there has been widespread debate in the human and social sciences regarding the compatibility and the relative merits of quantitative and qualitative approaches in research. In psychiatry, depending on disciplines and traditions, objects of study can be represented either in words or using two types of mathematization. In the latter case, the use of mathematics in psychiatry is most often only local, as opposed to global as in the case of classical mechanics. Relationships between these objects of study can in turn be explored in three different ways: 1/ by a hermeneutic process, 2/ using statistics, the most frequent method in psychiatric research today, 3/ using equations, i.e. using mathematical relationships that are formal and deterministic. The 3 ways of representing entities (with language, locally with mathematics or globally with mathematics) and the 3 ways of expressing the relationships between entities (using hermeneutics, statistics or equations) can be combined in a cross-tabulation, and nearly all nine combinations can be described using examples. A typology of this nature may be useful in assessing which epistemological perspectives are currently dominant in a constantly evolving field such as psychiatry, and which other perspectives still need to be developed. It also contributes to undermining the overly simplistic and counterproductive beliefs that accompany the assumption of a Manichean “quantitative/qualitative” dichotomy. Systematic examination of this set of typologies could be useful in indicating new directions for future research beyond the quantitative/qualitative divide.     

Structural analysis of the intension and extension of semantic concepts

The present studies examined the nature of visuo-spatial working memory development using conventional visual span and spatial span measures. Children aged between 6 and 13 years and adults aged 18-38 years were employed as participants. In Study 1, visual span, spatial span, articulation rate, and verbal fluency competencies were measured. In Study 2, visual span and spatial span maintenance was subject to five interference formats: nil, speech articulation, verbal fluency, visual masking, and spatial tapping. Distinct developmental rates were found for the two span tasks, which in the older children were correlated with the verbal fluency measure. Study 2 provided experimental evidence of the contribution of executive and spatial processes to spatial and to visual span maintenance. The results are interpreted as indicating that these memory span procedures make complex demands upon the visuo-spatial working memory architecture and consequently a precise identification of the process that actually develop is compromised. It is suggested that a componential approach where tasks are constructed to tap specific working memory components would afford a more accurate understanding of the development of these processes.     

The dilemma of localizing language: John Abercrombie's unexploited evidence

John Abercrombie (1780-1844) was considered the most eminent Scottish physician of his time. In his Pathological and Practical Researches on the Diseases of the Brain and Spinal Cord (1836, Edinburgh: John Carfrae and Son, 3rd ed.) he described the cases of 140 patients with cerebral disorders, 48 of whom suffered from language disturbances. Despite the overwhelming clinical and neuropathological evidence of a close association between language disorder and right-sided hemiparesis or diseases of the left hemisphere, and in spite of his great interest in language disorders, he made no attempt to localize the aphasic syndrome to a specific brain area.     

Effects of Exposure to Physique Slides on the Emotional Responses of Men and Women

The purpose of this study was to examine high and low body dissatisfied (BD) men's and women's in-task emotional responses to the acute exposure of sex-specific physique slides of the aesthetic ideal (i.e., ideal slides) and themselves (i.e., self-slides). Participants were 35 male and 30 female university students who reported their immediate in-task emotional responses (i.e., pleasure and arousal) to viewing the self- and ideal slides. It was found that the (a) high BD women reported the least amount of pleasure while viewing the self- and ideal slides; (b) women reported less pleasure while viewing the self-slides than did the men; (c) The high BD group reported less pleasure while viewing the self- vs. the ideal slides than did the low BD group, and (d) the high BD men reported the most arousal of any of the groups while viewing the self- and ideal slides. The differing emotional responses of the men and women and the high and low BD groups to viewing the self- vs. ideal slides are discussed, and future research directions are suggested.     

Collaboration,meaning‐making and therapy: What practitioners can learn from recent developments in qualitative research

Recent developments in qualitative research provide a rich resource of ideas and insights for counsellors and psychotherapists interested in postmodern approaches to theory and practice. The second edition of the landmark Handbook of Qualitative Research (Denzin and Lincoln, 2000) is discussed in terms of its potential value for therapists.     

Impacts of Home-Based Telework on Quality of Life for Employees and Their Partners. Quantitative and Qualitative Results From a European Survey

The study investigates the effects of home-based telework on quality of life (QoL). Four dimensions of QoL were analysed; overall satisfaction with life, sense of belonging, sense of becoming and sense of being. Through cross-national survey data (from 217 job holders and 112 partners) and by means of structural equation modeling, a positive association was found between home-based telework to a worker's sense of belonging (beta = 0.30, p < 0.001). On the other hand, a negative path was detected from the job holder's home-based telework to his or her partner's overall satisfaction with life (beta = –0.27, p < 0.05). After controlling for subdimensions of life quality, home-based work did not affect the job holder's overall life satisfaction. Moreover, the more concentration the job holder reported, the lower the sense of belonging was reported by his or her partner (beta = –0.28, p < 0.05). No simple explanation for the negative effects were found, but our interviews with the group of workers and their families leave us the impression that the problem of overworking and withdrawal was most relevant to the cases, in combination with negative spill-over effects and unclear boundary settings in the home.     

Getting curious about meaning-making in counselling (1)1

Counselling offers many experimental opportunities from which counsellors can learn and develop their meaning-making skills. Recent developments in qualitative research, and in social constructionist approaches to counselling, point to new ways of conceptualising the conversations of counselling and guidance. In particular, a hermeneutic view of counselling attunes counsellors and guidance practitioners to the particular meanings and meaning-making potentials clients and students bring to counselling and guidance conversations. Accordingly, our questions and proposed solutions can be seen as engaging the meaning-making efforts of clients in ways we, and they, can learn from. Our conversations offer many potential experiments in meaning-making, should we think of what others do with what we say—as occurring across a gap of conversational potential. This article explores ways to adopt, and learn from, such a hermeneutic frame in our conversations with clients and students.