Towards an understanding of unique and shared pathways in the psychopathophysiology of ADHD

Most attention deficit hyperactivity disorder (ADHD) research has compared cases with unaffected controls. This has led to many associations, but uncertainties about their specificity to ADHD in contrast with other disorders. We present a selective review of research, comparing ADHD with other disorders in neuropsychological, neurobiological and genetic correlates. So far, a specific pathophysiological pathway has not been identified. ADHD is probably not specifically associated with executive function deficits. It is possible, but not yet established, that ADHD symptoms may be more specifically associated with motivational abnormalities, motor organization and time perception. Recent findings indicating common genetic liabilities of ADHD and other conditions raise questions about diagnostic boundaries. In future research, the delineation of the pathophysiological mechanisms of ADHD needs to match cognitive, imaging and genetic techniques to the challenge of defining more homogenous clinical groups; multi-site collaborative projects are needed.     

Hemispheric differences for global/local processing in divided attention tasks: further evidence for the integration theory

Functional hemispheric asymmetries with respect to global/local processing have been observed more reliably in divided-attention than in selective-attention tasks. This difference has been accounted for by assuming that the hemispheres operate differently in the two tasks. In our study, the alternative hypothesis was tested that the interference between the global and local levels is increased under divided attention, and that this makes it necessary to base response selection on a more elaborated mental stimulus representation in which the levels and their content are integrated. Because the hemispheres systematically differ in this integration process, the increased interference between the levels explains why the corresponding asymmetries occur more reliably under divided attention. Two experiments supporting this hypothesis are reported, one with a divided and one with a selective attention task.     

What do men and women want in a partner? Are educated partners always more desirable?

Previous research has shown that males value a potential partner’s physical attractiveness more than females do, whereas females value a potential partner’s socioeconomic status (SES) more than males do. But are men really so unconcerned about a potential partner’s SES? Five studies revealed that men do integrate information about a woman’s SES into their decisions on whether to consider her as a romantic partner or not. Results consistently demonstrated that male participants preferred women with lower SES. Female participants, in contrast, preferred men with higher SES. These sex differences were more pronounced when a long-term romantic relationship rather than a one-night stand was being considered. In addition, men’s lower reported likelihood of romantic contact with a woman with high SES was due to her high educational level rather than her high income. Mediational analyses showed that men perceived a potential partner with high educational level as less likeable and less faithful, and thus reported less likelihood of romantic contact.     

Developmental changes in infants' processing of happy and angry facial expressions: a neurobehavioral study

Event-related brain potentials were measured in 7- and 12-month-old infants to examine the development of processing happy and angry facial expressions. In 7-month-olds a larger negativity to happy faces was observed at frontal, central, temporal and parietal sites (Experiment 1), whereas 12-month-olds showed a larger negativity to angry faces at occipital sites (Experiment 2). These data suggest that processing of these facial expressions undergoes development between 7 and 12 months: while 7-month-olds exhibit heightened sensitivity to happy faces, 12-month-olds resemble adults in their heightened sensitivity to angry faces. In Experiment 3 infants' visual preference was assessed behaviorally, revealing that the differences in ERPs observed at 7 and 12 months do not simply reflect differences in visual preference.     

Size matters: saccades during scene perception

We investigated the effect of image size on saccade amplitudes. First, in a meta-analysis, relevant results from previous scene perception studies are summarised, suggesting the possibility of a linear relationship between mean saccade amplitude and image size. Forty-eight observers viewed 96 colour scene images scaled to four different sizes, while their eye movements were recorded. Mean and median saccade amplitudes were found to be directly proportional to image size, while the mode of the distribution lay in the range of very short saccades. However, saccade amplitudes expressed as percentages of image size were not constant over the different image sizes; on smaller stimulus images, the relative saccades were found to be larger, and vice versa. In sum, and as far as mean and median saccade amplitudes are concerned, the size of stimulus images is the dominant factor. Other factors, such as image properties, viewing task, or measurement equipment, are only of subordinate importance. Thus, the role of stimulus size has to be reconsidered, in theoretical as well as methodological terms.     

Motor coordination uses external spatial coordinates independent of developmental vision

The constraints that guide bimanual movement coordination are informative about the processing principles underlying movement planning in humans. For example, symmetry relative to the body midline benefits finger and hand movements independent of hand posture. This symmetry constraint has been interpreted to indicate that movement coordination is guided by a perceptual code. Although it has been assumed implicitly that the perceptual system at the heart of this constraint is vision, this relationship has not been tested. Here, congenitally blind and sighted participants made symmetrical and non-symmetrical (that is, parallel) bimanual tapping and finger oscillation movements. For both groups, symmetrical movements were executed more correctly than parallel movements, independent of anatomical constraints like finger homology and hand posture. For the blind, the reliance on external spatial factors in movement coordination stands in stark contrast to their use of an anatomical reference frame in perceptual processing. Thus, the externally coded symmetry constraint evident in bimanual coordination can develop in the absence of the visual system, suggesting that the visual system is not critical for the establishment of an external-spatial reference frame in movement coordination.     

An accumulator model for responses and response times in tests based on the proportional hazards model

Latent trait models for responses and response times in tests often lack a substantial interpretation in terms of a cognitive process model. This is a drawback because process models are helpful in clarifying the meaning of the latent traits. In the present paper, a new model for responses and response times in tests is presented. The model is based on the proportional hazards model for competing risks. Two processes are assumed, one reflecting the increase in knowledge and the second the tendency to discontinue. The processes can be characterized by two proportional hazards models whose baseline hazard functions correspond to the temporary increase in knowledge and discouragement. The model can be calibrated with marginal maximum likelihood estimation and an application of the ECM algorithm. Two tests of model fit are proposed. The amenability of the proposed approaches to model calibration and model evaluation is demonstrated in a simulation study. Finally, the model is used for the analysis of two empirical data sets.     

The Others Will Help: The Presence of Multiple Video Game Characters Reduces Helping After the Game Is Over

The bystander effect refers to the phenomenon that individuals are less likely to help if there are potential other helpers present. For instance, past research revealed that participants were less likely to help computer-controlled characters if there were other computer-controlled characters present. Research has also shown that the bystander effect occurs if the presence of others is merely imagined. The present research examined the idea that the presence of multiple characters within a video game reduces the player's helping behavior even after the video game is over. In fact, participants who played a video game with multiple characters present were less likely to devote time to assisting in a future study than participants who had played the same video game with only a single character present.