Bayesian latent variable models for the analysis of experimental psychology data

In this paper, we address the use of Bayesian factor analysis and structural equation models to draw inferences from experimental psychology data. While such application is non-standard, the models are generally useful for the unified analysis of multivariate data that stem from, e.g., subjects’ responses to multiple experimental stimuli. We first review the models and the parameter identification issues inherent in the models. We then provide details on model estimation via JAGS and on Bayes factor estimation. Finally, we use the models to re-analyze experimental data on risky choice, comparing the approach to simpler, alternative methods.     

Depression and anxiety correlate with disease-related characteristics and quality of life in Chinese patients with gout: a case-control study

This study aims to evaluate the prevalence of depression and anxiety and investigate the potential risk factors for depression and anxiety in Chinese gout patients. A self-report survey was administered to 226 gout patients and 232 age- and gender-matched healthy individuals. Patients were asked to complete a set of standardized self-report questionnaires. Univariate and mutiple regression were used to analyze the data. We found 15.0% of gout patients had depression, and 5.3% had anxiety. After adjusted demographic variables, the prevalence of depression was significantly higher than the healthy controls (6.0%). There were significant correlations among education, total pain, disease duration, stage of gout, functional disability, number of tophi, number of flares/last year, presence of tender joints, nephropathy comorbidity, health-related quality of life (HRQoL), and psychological status. Meanwhile, logistic regression analysis identified number of tophi, functional disability, and mental component summary (MCS) as predictors of depression in gout patients. Education and MCS were significantly accounted for anxiety. In summary, the prevalence of depressive symptoms among gout patients was higher than healthy individuals. Education, disability, tophi and HRQoL were important risk factors linked to depression/anxiety in Chinese gout population.     

The relationship among resilience,rumination and posttraumatic growth in hemodialysis patients in North China

Research has indicated that clinical serious disease may lead to posttraumatic growth (PTG). However, little is known about PTG among hemodialysis (HD) patients. The study examined the relationship among resilience, rumination and PTG among Chinese HD patients. 196 HD patients were recruited from a tertiary hospital in a Northern city of China between 1 June 2015 and 30 May 2016. Patients were surveyed using the Posttraumatic Growth Inventory-Chinese version, Connor-Davidson Resilience Scale, and Chinese Event Related Rumination Inventory. Correlation analyses showed that resilience was most highly positively correlated with PTG (r = .70, p < .001), deliberate rumination moderately correlated to PTG (r = .50, p < .001), and intrusive rumination was lower negatively related to PTG (r = –.26, p < .001). Regression analyses showed that age, gender, duration of dialysis, resilience and deliberate rumination had significant associations with PTG (β = ?.31, p ＜ .0001; β = –.14, p = .002; β = .10, p = .032; β = .44, p < .001; β = .20, p < .001). They together explained 65% of the total variance in PTG (F [8,195] = 46.74, p < .001). However, intrusive rumination was not associated with PTG (p > .05). The results suggested that resilience and deliberate rumination may be instrumental for PTG improvement.     

Attachment,Social Support,Resilience and Posttraumatic Stress Disorder Symptoms in Chinese Adults Living with HIV/AIDS

The present study aimed to examine the effects of attachment, social support and resilience on posttraumatic stress disorder (PTSD) symptoms in people living with HIV/AIDS. One hundred fifty-two HIV+ adults in China were investigated. The results suggested that attachment anxiety had a significant direct effect on PTSD symptoms and impacted PTSD symptoms indirectly though associations with social support and resilience. Attachment avoidance could also be considered a distal risk factor of PTSD symptoms via the mediation of social support and resilience. The findings highlight the importance of identifying trauma and PTSD symptoms in people affected by HIV/AIDS and suggest that people with attachment anxiety and low social support resources might be at high risk for PTSD.     

晚期癌症患者静脉管理的重要性

恶性肿瘤作为我国的常见病、多发病,其死亡率高居首位。手术、化疗和放疗成为现代医疗对于癌症的常见治疗手段。中晚期癌症患者作为癌症临床诊疗对象的主体,常伴有各种慢性疾病或营养不良。从而,化疗、中药辅助巩固治疗及营养支持治疗成为中晚期癌症患者临床治疗过程中的主体。治疗方法决定给药途径,静脉输液成为了中晚期癌症患者治疗肿瘤的主...     

EGFR靶向治疗中敏感性预测指标的启示

EGFR抗肿瘤靶向治疗药物临床疗效存在明显个体差异,与其疗效敏感性相关的预测标志物能指导临床用药,成为临床关注的热点,本文从哲学的角度思考靶向治疗敏感性预测指标与恶性肿瘤的关系,试图以此为指导,更好地加强临床用药的预见性。     

Assessment of awareness of connectedness as a culturally-based protective factor for Alaska native youth

Research with Native Americans has identified connectedness as a culturally based protective factor against substance abuse and suicide. Connectedness refers to the interrelated welfare of the individual, one's family, one's community, and the natural environment. We developed an 18-item quantitative assessment of awareness of connectedness and tested it with 284 Alaska Native youth. Evaluation with confirmatory factor analysis and item response theory identified a 12-item subset that functions satisfactorily in a second-order four-factor model. The proposed Awareness of Connectedness Scale (ACS) displays good convergent and discriminant validity, and correlates positively with hypothesized protective factors such as reasons for living and communal mastery. The measure has utility in the study of culture-specific protective factors and as an outcomes measure for behavioral health programs with Native American youth.     

Knowledge-sharing intention in a virtual community: a study of participants in the Chinese Wikipedia

This study proposes a model for evaluating virtual community members' knowledge-sharing intention toward Chinese Wikipedia. The results of this study reveal that knowledge-sharing intention is influenced directly by attitude, subjective norms, and perceived behavioral control, whereas anticipated reciprocal relationships and enjoying helping are positively related to attitude; sense of self-worth and peer influences are positively related to subjective norms; and self-efficacy and resource-facilitating conditions are positively related to perceived behavioral control on knowledge sharing.     

青少年健康促进行为的调查研究

本研究采用青少年健康促进量表(Adolescent Health Promotion scale,AHP)以长沙市450名中学生为对象,对青少年的健康促进行为水平及其在不同性别、年龄和学校类型上的差异进行了调查和分析。研究结果表明,青少年在人际支持行为上得分最高,而在运动行为上得分最低;经分析,运动行为及人际支持行为上存在明显的性别差异;AHP的六个因子在不同年龄段和学校类型上均呈现显著差异。     

Y-Balance Test Performance and Leg Muscle Activations of Children with Developmental Coordination Disorder

This study compared Lower Quarter Y-Balance Test (YBT-LQ) performance and leg muscle kinetics between children with and without developmental coordination disorder (DCD), and investigated the association between YBT-LQ performance and muscle kinetics in children with DCD. Forty-eight children with DCD and 51 children without DCD participated in the study. Leg muscle kinetics were measured using surface electromyography when performing YBT-LQ. Children with DCD exhibited an overall lower YBT-LQ scores than controls. They had a lower peak gastrocnemius medialis activation for YBT-LQ posteromedial direction and shorter duration for the muscle to reach peak torque for YBT-LQ anterior direction. No relationship was found between YBT-LQ performance and leg muscle activations in children with DCD. Children with DCD exhibited a less competent YBT-LQ performance with atypical neuromuscular control.