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211.
Joint effect of dopaminergic genes on likelihood of smoking following treatment with bupropion SR. 总被引:1,自引:0,他引:1
Gary E Swan Lisa M Jack Ana M Valdes Huijun Z Ring Carl C Ton Susan J Curry Tim McAfee 《Health psychology》2007,26(3):361-368
OBJECTIVE: To determine the relationship between joint variation in 2 dopaminergic genes and the likelihood of nonsmoking following treatment with bupropion sustained release (SR). DESIGN: Three hundred twenty-three participants in a bupropion SR smoking cessation effectiveness trial with 12-month follow-up were genotyped for variants of dopamine receptor gene DRD2 and dopamine transporter SLC6A3. MAIN OUTCOME MEASURES: Self-reported 7-day point prevalence of nonsmoking. RESULTS: Neither genotype alone was associated with 7-day point-prevalent nonsmoking at the 12-month follow-up. However, in the presence of the DRD2 A1 allele, SLC6A3 status was significantly associated with the likelihood of nonsmoking at the 12-month follow-up (individuals with DRD2 A1+ and SLC6A3 9- were more likely to be smoking). In the absence of the DRD2 A1 allele, the association between SLC6A3 status and nonsmoking was nonsignificant. CONCLUSION: Although these results are suggestive, a more compelling test is needed of the hypothesis that dopaminergic gene interaction underlies, in part, the likelihood of smoking following treatment with bupropion SR. Most likely this will come from larger studies involving prospective randomization to treatment based on genotype. 相似文献
212.
Curran T DeBuse C Leynes PA 《Journal of experimental psychology. Learning, memory, and cognition》2007,33(1):2-17
Recognition memory requires both retrieval processes and control processes such as criterion setting. Decision criteria were manipulated by offering different payoffs for correct "old" versus "new" responses. Criterion setting influenced the following late-occurring (1,000+ ms), conflict-sensitive event-related brain potential (ERP) components: the stimulus-locked late posterior negativity (LPN) and the response-locked error-related negativity (ERN). The LPN-ERN were most negative to hits under conservative payoff conditions involving conflict between the correct old response and the payoff for new responses. This same conservative-hit condition was most frequently associated with response reversals when fast initial judgments were followed by slower judgments. Postresponse ERP activity may index conflict-sensitive processes underlying postretrieval cognitive control mechanisms involved with assessing responses to current items and updating response criteria on later trials. 相似文献
213.
Younger brains are noisier information processing systems; this means that information for younger individuals has to allow clearer differentiation between those aspects that are required for the processing task in hand (the ‘signal’) and those that are not (the ‘noise’). We compared toddler‐directed and adult‐directed TV programmes (TotTV/ATV). We examined how low‐level visual features (that previous research has suggested influence gaze allocation) relate to semantic information, namely the location of the character speaking in each frame. We show that this relationship differs between TotTV and ATV. First, we conducted Receiver Operator Characteristics analyses and found that feature congestion predicted speaking character location in TotTV but not ATV. Second, we used multiple analytical strategies to show that luminance differentials (flicker) predict face location more strongly in TotTV than ATV. Our results suggest that TotTV designers have intuited techniques for controlling toddler attention using low‐level visual cues. The implications of these findings for structuring childhood learning experiences away from a screen are discussed. 相似文献
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216.
Tim S. Müller Nan Dirk De Graaf Peter Schmidt 《Journal for the scientific study of religion》2014,53(4):739-759
Religious socialization occurs within the immediate family as well as in the broader social context. Previous research has shown that parents’ religiosity matters less for the transmission of religious beliefs in devout than in secular nations, implying smaller costs of religious socialization. In this article we test which other societal factors affect the transmission of religious beliefs: anti‐religious policies in formerly socialist countries, economic development, and income inequality. Our results indicate that societies with high levels of income inequality seem to provide the most favorable context for religious socialization. Individuals develop strong religious beliefs even if they only received little religious socialization within the family. Formerly socialist nations increased socialization costs through the overall suppression of religious practice. Economic development has no impact on socialization effects, suggesting that inequality is a more important driver of religious change than previously thought. 相似文献
217.
Mary A. Pyc David A. Balota Kathleen B. McDermott Tim Tully Henry L. Roediger III 《Memory & cognition》2014,42(6):965-977
Although the benefits of spaced retrieval for long-term retention are well established, the majority of this work has involved spacing over relatively short intervals (on the order of seconds or minutes). In the present experiments, we evaluated the effectiveness of spaced retrieval across relatively short intervals (within a single session), as compared to longer intervals (between sessions spaced a day apart), for long-term retention (i.e., one day or one week). Across a series of seven experiments, participants (N = 536) learned paired associates to a criterion of 70 % accuracy and then received one test–feedback trial for each item. The test–feedback trial occurred within 10 min of reaching criterion (short lag) or one day later (long lag). Then, a final test occurred one day (Exps. 1–3) or one week (Exps. 4 and 5) after the test–feedback trial. Across the different materials and methods in Experiments 1–3, we found little benefit for the long-lag relative to the short-lag schedule in final recall performance—that is, no lag effect—but large effects on the retention of information from the test–feedback to the final test phase. The results from the experiments with the one-week retention interval (Exps. 4 and 5) indicated a benefit of the long-lag schedule on final recall performance (a lag effect), as well as on retention. This research shows that even when the benefits of lag are eliminated at a (relatively long) one-day retention interval, the lag effect reemerges after a one-week retention interval. The results are interpreted within an extension of the bifurcation model to the spacing effect. 相似文献
218.
Gavin P. Lawrence Victoria E. Cassell Stuart Beattie Tim Woodman Michael A. Khan Lew Hardy Vicky M. Gottwald 《Psychological research》2014,78(5):634-650
We investigated for the first time whether the principles of specificity could be extended to the psychological construct of anxiety and whether any benefits of practicing with anxiety are dependent on the amount of exposure and timing of that exposure in relation to where in learning the exposure occurs. In Experiment 1, novices practiced a discrete golf-putting task in one of four groups: all practice trials under anxiety (anxiety), non-anxiety (control), or a combination of these two (i.e., the first half of practice under anxiety before changing to non-anxiety conditions, anxiety-control, or the reverse of this, control-anxiety). Following acquisition, all groups were transferred to an anxiety condition. Results revealed a significant acquisition-to-transfer decrement in performance between acquisition and transfer for the control group only. In Experiment 2, novices practiced a complex rock climbing task in one of the four groups detailed above, before being transferred to both a high-anxiety condition and a low-anxiety condition (the ordering of these was counterbalanced across participants). Performance in anxiety transfer was greater following practice with anxiety compared to practice without anxiety. However, these benefits were influenced by the timing of anxiety exposure since performance was greatest when exposure to anxiety occurred in the latter half of acquisition. In the low-anxiety transfer test, performance was lowest for those who had practiced with anxiety only, thus providing support for the specificity of practice hypothesis. Results demonstrate that the specificity of learning principle can be extended to include the psychological construct of anxiety. Furthermore, the specificity advantage appears dependent on its timing in the learning process. 相似文献
219.
Ownership Status and the Representation of Assets of Uncertain Value: The Balloon Endowment Risk Task (BERT)
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Owners tend to overvalue possessions relative to non‐owners: a phenomenon known as the endowment effect. In three experiments, using markets for goods of uncertain value, we investigated whether this can be partly attributed to misperceiving an asset's profitability or to uncertainty about a good's utility. To test our hypotheses, we devised the Balloon Endowment Risk Task, in which participants can sell or buy their right to participate in the Balloon Analogue Risk Task. Once purchased/retained, a virtual balloon is pumped to accrue money, which is lost if the balloon bursts. Participants first learn about the risky asset (balloon) by observing others playing the Balloon Analogue Risk Task before they enter the market. In Experiment 1, we replicated the endowment effect; yet, owners and non‐owners predicted pumping the same number of times and subsequently did so when given that opportunity. In Experiments 2 and 3, the level of uncertainty about the balloon's profitability was manipulated by modifying the number of bursts that participants viewed in the initial learning stage. When more diagnostic information was provided, making the average burst point easier to estimate and reducing value uncertainty and increasing confidence in valuation, the endowment effect diminished although mean estimates of the average burst point did not differ between owners and non‐owners. Thus, endowment effects were partly attributable to value uncertainty but could not be explained by owners and non‐owners having divergent perceptions of the asset's payoff distribution. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
220.
Some researchers suggest that the way a teacher is perceived during the first encounter with a classroom group resembles, and therefore is predictive of, later classroom processes as perceived by students. This study investigated the degree to which interpersonal ratings (i.e., control and affiliation), given by secondary school students to teachers unknown to them, are comparable to ratings given by students who are well acquainted with that teacher, by means of a quasi-experimental design. Ratings concerning a teacher students had not met before, based on a 5 min video vignette, were compared to ratings given by students who had been taught by the same teacher for at least a year (N $\,{=}\,$ 489). Students at no acquaintance perceived a teacher’s interpersonal traits in a similar way as students who were familiar with that teacher. It is concluded that students’ early interpersonal perceptions of a teacher largely resemble perceptions formed by students that know this teacher well. 相似文献