Psychotherapeuten ins Internet

This contribution provides recommendations and guidelines for the development of a Web site for psychotherapists, whereby the conception of the presentation predominates. In comparison, practical realisation and care of the site require only a relatively small effort. The way to a Web appearance is presented in seven steps. In addition, the way to deal with (unwanted) e-mail will be considered. The article is centered on clarity and practice orientation.     

Cytokine-Purine Interactions in Behavioral Depression in Rats

This paper reviews recent findings from our laboratories concerning metabolic and immune mediators of behavioral depression in rats. Specifically, a single injection of 6 mg/kg of reserpine substantially increases behavioral depression, as evidenced by an increase in the amount of time spent floating by independent groups of rats tested for swim performance at various times during the next week. The behavioral impairment consists of two components. An early component emerges one hour after reserpine treatment and persists for about 24 hours. The deficit is not reversed by intracranial ventricular infusion of the receptor antagonist for interleukin-1beta (IL-1beta). A second, late-component deficit appears approximately 48 hours after reserpine treatment and recovers within a week. Late-component depression is reversed by central infusion of the IL-1beta receptor antagonist, and is mimicked by central infusion of the proinflammatory cytokine. Importantly, both early and late components of reserpine-induced depression and IL-1beta induced depression are reversed by a systemic injection of the highly selective A2A adenosine receptor antagonist 8-(3-Chlorostyryl) caffeine. These data are discussed in terms of the overlap in the conservation-withdrawal reaction during sickness, traumatic stress, and major depression and the regional contribution of purines and cytokines to the organization of this reaction in the brain.     

A job with a future? Delay discounting, magnitude effects, and domain independence of utility for career decisions

Decision-makers are often faced with inter-temporal choices in which they are required to choose between options that differ in both value of and delay to outcomes. In this study, assumptions of Discounted Utility Theory (DU) were tested within inter-temporal career choices. According to DU, the same discount rate should be applied regardless of the amount of delay and magnitude of the outcome. In addition, DU predicts that, for economic substitutes, the same discount rate should be applied to both commodities. Contrary to assumptions of DU, but consistent with a hyperbolic discounting model, graduating college students’ job choices reflected non-constant discount rates (i.e., Delay Effect) for future salary and preferred tasks. In addition, these students exhibited lower discount rates for salary and percentage of preferred tasks (i.e., Magnitude Effect). Finally, the two were not found to be economic substitutes as there was a low correlation between discount rate for salary and percentage of preferred tasks (i.e., Domain Independence). Implications for employee recruitment and human resource management are discussed.     

Optimizing the scientific study of suicide with open and transparent research practices

Suicide research is vitally important, yet—like psychology research more broadly—faces methodological challenges. In recent years, researchers have raised concerns about standard practices in psychological research, concerns that apply to suicide research and raise questions about its robustness and validity. In the present paper, we review these concerns and the corresponding solutions put forth by the “open science” community. These include using open science platforms, pre‐registering studies, ensuring reproducible analyses, using high‐powered studies, ensuring open access to research materials and products, and conducting replication studies. We build upon existing guides, address specific obstacles faced by suicide researchers, and offer a clear set of recommended practices for suicide researchers. In particular, we consider challenges that suicide researchers may face in seeking to adopt “open science” practices (e.g., prioritizing large samples) and suggest possible strategies that the field may use in order to ensure robust and transparent research, despite these challenges.     

A case of subcortical dementia due to sarcoidosis of the hypothalamus and fornices

A patient with sarcoidosis involving predominantly the hypothalamus and fornices was evaluated for dementia. He showed a relative sparing of fund of knowledge and orientation. Memory skills, particularly short-term memory, were severely impaired. Behavioral changes included apathy and a lack of spontaneity. Insight was relatively preserved. The pattern of his deficits showed some similarities to the pattern reported in patients with Huntington's disease and was different from that described in Alzheimer's disease. The dementia caused by subcortical pathology may differ in important respects from that caused by diffuse cortical dysfunction.