大鼠作业成绩与脑内亮氨酸脑啡肽含量变化的相关性研究

本工作采用穿梭式电击回避反应法和脑啡肽的放射免疫测定法,分析比较了大鼠作业成绩与脑内壳氨酸脑啡肽(Leu-enkephalin,LEK)含量的关系,在本实验条件下,观察到作业成绩不良组纹状体内LEK含量显著高于成绩优良组和对照组,并由实验证明,它们之间的差异不是由于在实验中接受电击的次数或电击总量不同造成的。这一结果提示,内源性亮氨酸脑啡肽可能参与记忆获得的调制。     

学前和初小儿童智能筛查——图片词汇测试法

美国L.M.Dunn 1965年修改发表的皮勃迪图片词汇测试(PeabodyPicture Vocabulary Test简称PPVT)目前仍是美国智力不足协会(AAMD)所介绍的常用智能测试方法之一。本文参考PPVT制订出适合我国城市学前期与小学初期儿童的图片词汇测试;在上海市区进行标准化;制订了智龄量表、智商和百分位数量表。本测试再测信度r=0.945,二测试者间信度r=0.913。奇偶信度r=0.945,测试标准误σ=4.5。本方法与“学前儿童能力筛查五十项”,“画人试验”,“WPPSI”总智商、语言智商、操作智商,语文成绩,算术成绩的效度相关分别为:r=0.478,r=0.466,r=0.590,r=0.531,r=0.427,r=0.652,r=0.609。本测试制订以来已经数千人次应用,证明是一种简便易行,省时经济,准确性较好,且能进行集体测试的学前及小学初期儿童一般智能(generalintelligence)的筛查方法(Screening test)。     

Theology After the Scientific Revolution: The Significance of Nancey Murphy’s Contribution to Philosophy of Religion

This paper evaluates Nancey Murphy’s contribution to philosophy of religion paying special attention to epistemology and ethics. I argue that Murphy’s intellectual moves are motivated by a reflective and constructive engagement—around particular loci such as human knowledge, divine action, and the moral nature of the universe—with reductive materialism as a rival tradition of inquiry. At paper’s end, I suggest an amendment in Murphy’s contribution to ethics.     

Child Conduct Problems Across Home and School Contexts: a Person-Centered Approach

To examine patterns of conduct problems across the home and school context, we used latent class analysis to analyze primary caregivers’ and teachers’ ratings on the conduct problems subscale of the Strengths and Difficulties Questionnaire (Goodman Journal of Child Psychology and Psychiatry, 38, 581–586, 1997) in the Family Life Project (N?=?1,292), a prospective study of child development in rural and small town contexts. We found a similar four-class solution at 5 and 7 years of age. In decreasing prevalence, the following classes were identified: (1) low symptoms reported by both informants (low cross-context); (2) high parent-reported symptoms, low teacher-reported symptoms (home context); (3) low parent-reported symptoms, moderate teacher-reported symptoms (school context); and (4) high symptoms reported by both informants (high cross-context). Classes exhibited stability from age five to age seven: children were more likely to remain in the same class than to transition to a different class, and longitudinal stability was especially high for children in the low cross-context class at age 5. A number of child and family characteristics measured in early childhood (executive function, verbal ability, poverty-related risk, sensitive parenting, and parental depressive symptoms) were associated with class membership at age five and age seven, but were generally not associated with longitudinal transitions between classes.     

胸腺功能的发现及其对免疫学发展的影响

19世纪60年代初,免疫系统的发现使免疫学的发展方向发生了革命性转变。在这场转变的过程中,胸腺功能的发现起到了重要的作用。详述了胸腺功能的发现过程,并进一步深入到免疫学思想史,讨论了这个发现如何影响了免疫学的历史进程。     

全球流感大流行与共建和谐社会

科学家预测:新一轮流感大流行不可避免。通过总结历史教训,分析目前可能引起流感大流行的原因,展开预防流感大流行与共建和谐社会关系的讨论。     

终末期癌症病人诊治中的心理特征与人文关怀

在诊治终末期癌症病人过程中不仅要关心他们的躯体方面,更要关心他们的心理方面,在诊治过程中要根据他们的独特的心理特征来进行人文心理关怀,维持生命质量和保证他们应有的人格尊严.     

脓毒症及其治疗策略的反思

脓毒症是各种严重创伤、烧伤、缺氧、再灌注损伤及外科大手术常见的并发症.目前脓毒症休克的临床病死率仍高达50%以上.对脓毒症发病机制的进一步深入认识和现行治疗措施的反思有助于改善其临床防治.