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Depression has been reported to be associated with a greater risk of death and cardiovascular disease (CVD); however, the impact of antidepressants (ADM) on CVD risk remains controversial. Statin use is known to decrease CVD risk. Whether the use of these medications together affects CVD risk has not been studied. Patients (N = 26,828) completing the patient health questionnaire (PHQ-9), ≥40 years of age, without prior CVD, and no prior ADM use were studied. Depressive severity was categorized as none-mild (PHQ-9 score ≤14, n = 21,517) and moderate-severe (PHQ-9 score ≥15, n = 5311). Cox hazard regression was used to evaluate the association of no ADM/no statin use (n = 23,104 [86.1%]), ADM/no statin use (n = 877 [3.3%]), no ADM/statin use (n = 2627 [9.8%]), and ADM/statin use (n = 220 [.8%]) with major adverse cardiovascular events (MACE: death, CAD, stroke). Patients averaged 56 ± 12 years; 61% female. There were 1182 (4.4%) 3 year MACE events. The association of ADM and statin use with MACE varied by depressive symptom severity, with statin therapy associated with a decreased risk in the none-mild group (HR = .78, p = .007) and ADM in the moderate-high group (HR = 0.58, p = 0.02). Concomitant use of ADMs and statins did not appear to provide additive benefit.  相似文献   
274.
This study evaluated whether a participatory action research intervention with nursing staff on acute care older people National Health Service wards in the United Kingdom was effective for increasing work engagement. Mediation analyses between job resources (social support, influence in decision-making), job demands, work-related needs (autonomy, competence, relatedness), and work engagement explored the presumed psychological mechanisms underlying the intervention. A non-randomized, matched control group, pretest, post-test design involved three intervention and five control wards. A significant decrease in relatedness, and a borderline significant decrease in competence, was observed in the intervention group compared to the control group, with no effect on work engagement (N = 45). Work-related needs mediated between resources and work engagement, supporting the job demands-resources model and self-determination theory as an underlying explanatory theory. Intervention implementation was difficult, highlighting the need for participant and organizational readiness for change, and strong management support. This is the first known study to apply participatory techniques to increase work engagement in nursing staff and explore the underlying explanatory psychological mechanisms, offering a novel means of taking work engagement research forward. Crucially, it highlights the challenges involved in intervention research and the importance of including evaluations of intervention implementation alongside statistical evaluations to avoid erroneous conclusions.  相似文献   
275.
The Overall Managerial Readiness (OMR) scale was first developed as a simple measure of managerial potential for the Chinese workforce. OMR purports to predict managerial performance by assessing a person's attitudes and intention to engage in managerial practices. It consists of 28 forced‐choice statements most of which refer to attitudes and behaviors in a work setting. Three studies together showed that OMR was correlated negatively with neuroticism, and positively with conscientiousness, agreeableness, openness to experience, and extraversion. Notwithstanding, OMR was distinct from the Big Five, and had incremental predictive power on work performance (Study 3). Besides, OMR alone predicted bank managers' productivity (Study 4). Finally, internal consistency and concurrent validity of a Likert version of OMR was ascertained (Study 5).  相似文献   
276.
Two experiments compared 7- and 8-year-olds' and 9- and 10-year-olds' ability to use semantic analysis and inference from context to understand idioms. We used a multiple-choice task and manipulated whether the idioms were transparent or opaque, familiar or novel, and presented with or without a supportive story context. Performance was compared with that of adults (Experiment 1) and 11- and 12-year-olds (Experiment 2). The results broadly support Cacciari and Levorato's global elaboration model of figurative competence with a notable exception: Even the youngest children were able to use semantic analysis to derive the meanings of transparent idioms as well as being sensitive to meaning in context. The findings show that young children process language at both the small-grain phrase level and the discourse level to establish figurative meaning, and they demonstrate that the language processing skills that aid idiom comprehension, as well as idiom knowledge itself, are still not fully developed in 11- and 12-year-olds.  相似文献   
277.
The cost of incongruent stimuli is reduced when conflict is expected. This series of experiments tested whether this improved performance is due to repetition priming or to enhanced cognitive control. Using a paradigm in which Word and Number Stroop alternated every trial, Experiment 1 assessed dynamic trial-to-trial changes. Incongruent trials led to task-specific reduction of conflict (trial n + 2) without cross-task modulation (trial n + 1), but this was fully explained by repetition priming. In contrast, an increased ratio of incongruent words did lead to sustained task-specific enhancement, above and beyond repetition priming (Experiment 2). Experiments 3 and 4 assessed the voluntary modulation of cognitive control: A cue predicted the congruency of the incoming trial, allowing participants to establish the correct mindset (Word Stroop in Experiment 3, Flanker task in Experiment 4). Preparing oneself to process an incongruent word (or flanker) enhanced conflict resolution in the subsequent Number Stroop, an example of cross-task modulation. Taken together, these experiments reveal the multifaceted aspects of conflict resolution: Trial-to-trial changes are often due to repetition priming; sustained modulations brought about by task demands are task specific; and voluntary modulations are task general.  相似文献   
278.
A contiguity effect-the finding that stimuli that occur close together in time become associated to each other--is observed between words that are separated by several seconds. The traditional account of contiguity effects is that item representations become associated to each other while active in a short-term memory buffer--a limited-capacity store that can hold a small, integral number of items. Participants studied and free recalled 48 lists of words. At the end of the session, participants were given a surprise final free recall test on all of the items from all of the lists. In addition to a standard contiguity effect between items presented at nearby serial positions, we simultaneously observed a contiguity effect between items presented in different lists. This latter contiguity effect extended over several lists, or several hundred seconds, well beyond the range that can be attributed to a buffer holding a small, integral number of items.  相似文献   
279.
This study investigated the effectiveness of functional behavioral assessment (FBA)—informed interventions for sleep problems, particularly co‐sleeping, in children with autism spectrum disorder (ASD). Seven children, who exhibited multiple sleep problems including unwanted co‐sleeping, participated. FBA, based on information derived from interviews and parent‐recorded sleep diaries, was used to develop individualized case formulations upon which multicomponent, parent‐implemented interventions were based. These were evaluated using a single‐case, non‐concurrent multiple‐baseline‐across‐participants design. Improvements were observed across all sleep problems, including the elimination of co‐sleeping. Gains were maintained at follow‐up for five out of seven children, though two children did not complete intervention. Parents reported high levels of satisfaction with the program. FBA‐based interventions for sleep problems in children with ASD and their clinical implications are further discussed.  相似文献   
280.
Work engagement is associated with important individual and organisational outcomes (e.g. employee health and well-being, performance). This narrative systematic review aims to synthesise the increasing number of work engagement interventions and inform future research by exploring: (1) the specific intervention foci, delivery methods and content of engagement interventions; (2) intervention effectiveness; and (3) underlying mediators and moderators. A systematic search for interventions employing a validated engagement measure revealed 40 studies. Five were personal resource building, twelve job resource building, three leadership training, eighteen health promotion, and two job and personal resource building. Twenty (50%) studies observed significant positive effects on work engagement, two (5%) had a negative effect, and eighteen (45%) had no effect. Job and personal resources, job demands and well-being were important mediators. Moderators included the specific intervention focus and delivery method, employee participation, manager support, and intervention level (top-down vs bottom-up). Bottom-up interventions, and job crafting and mindfulness interventions particularly, were most successful. Implementation difficulties were common, including poor response and attrition rates, and adverse factors (e.g. organisational restructuring, redundancy, economic downturn). We highlight implications for research and practice and stress the need to test underlying theories to build knowledge around how, why, and when interventions work.  相似文献   
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