Counseling and screening for cystic fibrosis in patients with congenital bilateral absence of the vas deferens: Patient perceptions

Congenital bilateral absence of the vas deferens (CBAVD) occurs in approximately 1.3% of infertile males and is thought to be, in most cases, a primarily genital form of cystic fibrosis (CF). Fourteen males with CBAVD considering microsurgical sperm aspiration from the epididymis (MESA) and in vitro fertilization were seen for genetic counseling and screening for CF. To retrospectively evaluate these patients' perceptions of the counseling and screening information, we conducted structured telephone interviews to assess their recall of information about CF and its impact on their health concerns and reproductive plans. We found that, as the health implications of CF are abstract and not as important to patients as the diagnosis of CBAVD itself, patients tend to view their CF status primarily in terms of their reproductive potential. Retrospective analysis afforded us an opportunity to identify the psychosocial issues of most concern to this unique patient population.     

The morphological asymmetry of the hemispheres and cerebral dominance for speech: A possible relationship

The asymmetry of the posterior Sylvian branches of the middle cerebral artery was examined on the carotid angiograms of 59 patients in whom the lateralization of speech representation was known from sodium amobarbital (Amytal) studies. The usual asymmetry of these vessels was found to be present in the group of patients with left-hemisphere speech representation but significantly reduced in patients with atypical cerebral dominance for speech. A model of the inheritance of handedness and cerebral dominance is extended to take account of these results.     

Regional cerebral blood flow response to recognition memory versus semantic classification tasks

Two randomly assigned groups, N = 7 each, of neurologically normal patients were composed. One group, RM, had regional cerebral blood flow measurements during a recognition memory probe test; the other group, SC, had rCBF measurements during a semantic classification task, using the same stimulus and response features as the RM task. Thus, the groups differed only in the cognitive instruction they were executing. The RM group showed a significantly lower change from resting baseline to activation, in mean left hemisphere initial slope index, than did the SC group. The RM group, but not the SC group, showed a significant inverse correlation between occipital flow and accuracy of memory performance as indicated by d′. Correlations between age and hemispheric initial slope index, and between homologous left and right hemisphere sites, were also described. The results are considered to support an anatomical basis for the distinction between episodic and semantic memory and to suggest that occipital flow may diminish with accurate memory performance because of an upstream demand of blood in the medial temporal lobes.     

Asymmetrical effects of positive and negative events: the mobilization-minimization hypothesis

Negative (adverse or threatening) events evoke strong and rapid physiological, cognitive, emotional, and social responses. This mobilization of the organism is followed by physiological, cognitive, and behavioral responses that damp down, minimize, and even erase the impact of that event. This pattern of mobilization-minimization appears to be greater for negative events than for neutral or positive events. Theoretical accounts of this response pattern are reviewed. It is concluded that no single theoretical mechanism can explain the mobilization-minimization pattern, but that a family of integrated process models, encompassing different classes of responses, may account for this pattern of parallel but disparately caused effects.     

ODAP: a stand-alone program for observational data acquisition

A software program written to collect real-time, observational data is described. The flexible program allows customized behavior codes and observational durations and simultaneously records both timed and counted events. The data are collected by means of single keystrokes, automatically stored to disk with 100th of a second resolution and summarized for each observational session. The program’s database files are dBASE III PLUS compatible and may be browsed, edited, or converted to ASCII files from the program’s main menu. Field testing demonstrated the efficiency and interobserver reliability of the program (for frequency,r=0.81; for durational behaviors,rs=0.89 and 0.96). The software operates on IBM XT/AT/PS 2s and most clones with PC/MS DOS version 2.0 or greater.     

Assessing social competencies in lower income preschool children

This study examined social competencies in 4-year-old, lower income, nonwhite preschool children in a replication of work by Shure, Spivack, and Jaeger. Age differential interpersonal cognitive problem-solving skills were investigated, i.e., ability to generate alternative solutions to interpersonal problems, consequential thinking, and school achievement as they relate to behavioral adjustment ratings by teachers and independent observers. A teacher's rating of a child as aberrant or adjusted predicted an independent observer's rating of that child in a naturalistic setting. Children who were rated as adjusted by their teachers had significantly higher scores on an achievement inventory than those children who were rated aberrant, but the study did not find the predicted relationship between problem-solving thinking and adjustment. A version of this paper was presented at the annual meeting of the American Psychological Association, New York, September 1979. The study was supported by grants from the McGregor Fund, the Eloise and Richard Webber Foundation, the David M. Whitney Fund and by the Detroit Public Schools Region 7, for which the authors express grateful appreciation. The authors also wish to thank Myrna B. Shure for her help in carrying out this replication.