The effects of changing the phase and duration of sleep.

The relative effects of extended sleep, reduced sleep, and shifts of habitual sleep time on subsequent performance and mood were studied. Ten healthy male university students who regularly sleep 9.5-10.5 hr were the subjects. Measurements were obtained from a 45-min auditory vigilance task, a 5-min experimenter-paced addition task and a mood adjective check list 30 min after awakening, at midday, and in the evening following five electroencephalographically recorded nights of sleep. The experimental treatments compromised at 9.5-10.5 hr habitual sleep condition and four conditions in which the regular sleep period was lengthened, reduced, delayed, and advanced by 3hr. Following each 3-hr altered condition of sleep there was an equivalent decline in vigilance performance and in subjective arousal as measured by the mood scales. Together with other recent evidence, the present results support the hypothesis that acute disruption of the 24-hr sleep-wakefulness cycle produces degradations in human performance largely independent of total sleep time.     

An operant approach to rehabilitation medicine: overcoming learned nonuse by shaping.

A new approach to the rehabilitation of movement, based primarily on the principles of operant conditioning, was derived from research with deafferented monkeys. The analysis suggests that a certain proportion of excess motor disability after certain types of injury involves a learned suppression of movement and may be termed learned nonuse. Learned nonuse can be overcome by changing the contingencies of reinforcement so that they strongly favor use of an affected upper extremity in the chronic postinjury situation. The techniques employed here involved 2 weeks of restricting movement of the opposite (unaffected) extremity and training of the affected limb. Initial work with humans has been with chronic stroke patients for whom the approach has yielded large improvements in motor ability and functional independence. We report here preliminary data suggesting that shaping with verbal feedback further enhances the motor recovery.     

君子不忧不惧：君子人格与心理健康——自我控制与真实性的链式中介

基于儒学经典命题提出君子人格通过自我控制与真实性的链式中介对心理健康产生正向效应的假设, 运用多种方法进行验证(总样本量为1169)。结果表明, 君子人格正向预测同时测量的心理健康(研究1)和6个月后测量的自尊、核心自我评价、情感平衡, 负向预测心理症状(研究4); 君子人格正向预测自我控制特质(研究1)和自我控制决策(研究3和研究4), 受到情境模拟操纵的自我控制提升心理健康与真实性(研究2), 受到回忆启动操纵的真实性提升心理健康(研究3); 链式中介作用也得到了同时和跨时间点测量、统计控制和实验控制等多方法结果的支持。君子人格水平较高的人, 更易自我控制, 由此感到自己的行为与真实自我更加一致与贯通, 因此具有更积极的心理状态。     

论医学的人本体及其文化内核

人和"人的世界"是系统的存在与演化过程,人和"人的世界"是文化的世界和流变。人,是人和"人的世界"的本体,文化是人和"人的世界"的内核及其展开。医学世界也是系统的存在与演化过程,是医学文化的展开与流变。医学人是医学世界的本体,医学文化内核及其展开形成医学世界,医学世界是医学文化流变的世界。     

多通道变化盲:理论、方法与进展

人们在特定条件下通常难以探测到事物的变化,这种现象发生在视、听、触感觉通道分别称为变化盲视、变话盲听和变化盲触。文章主要对以下四个方面进行详细的探讨:变化盲视及视觉表征理论、变化盲听及听觉信息加工机制、变化盲触及体表空间表征、多通道变化盲及空间注意和空间表征跨通道一致性本质。此外,文章还对多通道变化盲的理论深度和拓展方向及相关应用研究进行了展望。     

腹膜间皮细胞EMT在腹膜纤维化中的研究进展及意义

腹膜透析是终末期肾衰患者肾脏替代治疗的重要手段,腹膜纤维化导致腹透效能下降及超滤衰竭,制约着腹膜透析的应用.腹膜间皮细胞上皮细胞间充质转化是腹膜纤维化的起始和可逆环节,因此预防和逆转EMT的发生发展可能是阻止和延缓腹膜纤维化、超滤衰竭的最佳策略,并将带来巨大的社会和经济效益.     

The effect of set on encoding and rehearsal processes in memory

An experiment was conducted to determine the effect of manipulating S’s preparation for what he will see on a given trial on his ability to mentally keep track of the number of occurrences of each of several different stimuli in a sequence. It was found that, when the same stimuli were used from trial to trial, performance was significantly better than when different stimuli were used. Foreknowledge of the specific stimuli to be used on a given trial did little to improve performance per se, but it did reduce labeling errors. The results were discussed in terms of the “spatial window” model of keeping-track performance.