A Case of Partial Biotinidase Deficiency Associated With Autism

We report the case of a child with partial biotinidase deficiency and autistic developmental disorder. We arrived at the diagnosis of biotinidase deficiency when the child was almost 4 years of age. Consequently, he began cofactor biotin treatment (10 mg daily) which did not resolve his autistic behavior. His younger brother was affected by partial biotinidase deficiency diagnosed at birth through our neonatal screening program. He was precociously treated with cofactor biotin therapy (10 mg daily) and did not show any behavioral abnormality or developmental delay. Since the brain is quite vulnerable to biotin deficiency, delayed biotin therapy could result in neurological damage. Our patient is the first case of partial biotinidase deficiency associated with autism. We hypothesize that the low biotinidase activity could have caused biotin deficiency in his brain and cerebrospinal fluids and consequently serious neurological problems, such as stereotyped and autistic behaviors, which were irreversible in spite of biotin supplementation.     

Intercultural Study of Personal Space: A Case Study

The study of intercultural differences in personal space attempts to identify factors that could be helpful in guiding people from different cultures to live and work together in international ventures. The objective of this research was to measure interpersonal distance in a cross-cultural environment. Twenty-three participants classified in 4 cultural groups answered an 11-questions interview where the personal distance and orientation between seated interactants were measured. Results showed that Anglo Saxons used the largest zone of personal space, followed by Asians, then Caucasians, and, as expected, Mediterraneans and Latinos used the shortest distance. Where Latinos adopt a face-to-face position, Caucasians tend to orient themselves to the side of the interviewer, which has an impact on interpersonal communication.     

Sexuality and Health Among Chinese Seniors in Canada

Research on sexuality among older immigrants is extremely inadequate. This paper presents the results and analysis based on a national survey using a random sample of 2,272 Chinese-Canadian seniors. Self-reported health is examined in relation to a range of demographic as well as sexuality variables. Logistic regression analysis shows that language (English) ability and income play an important role in the health of Chinese-Canadian seniors, along with the sexuality variables. Among men, both the frequency of sexual activity and satisfaction with sex life have a positive effect on health. Among women, only sexual satisfaction is found to be significant. Results from this study can inform future research, service delivery, and policymaking in health care and social service for seniors.     

Don’t Shoot the Messnger: Memory for Misspellings in Context

Misspellings in sentences are usually easy to understand by readers due to top-down influences. Although top-down processing allows for fluent reading of misspelled items, the nature of their representations in memory is not known. If representations of misspellings are distinct from representations of correctly spelled words, their influence should be seen in later recognition decisions. In this set of experiments, participants read words and misspellings embedded in sentences and were later given a recognition test. The sentences contained semantically biased or neutral contexts. In Experiment 1, misspellings were created by removing a single letter (e.g., drveway). In Experiment 2, the recognition items probes were presented in uppercase letters (e.g., DRVEWAY) to reduce the visual similarity between study and test items. In Experiment 3, the misspellings were created by substituting visually similar letters (e.g., driweway). In contrast to the previous experiments, in Experiment 4, participants were explicitly told about the memory test to see how response strategies affect performance. Overall, the results indicate that people retain surface feature information about misspellings which seem to inform their memory judgments, and that the processing of this information cannot be strategically controlled.     

Functional equations arising in a theory of rank dependence and homogeneous joint receipts

This paper focuses on a class of utility representations of uncertain alternatives with two possible consequences (binary gambles) when they are linked via a distributivity property called segregation to an operation of joint receipt, which may be non-commutative. The assumption that the gambling structure and the joint receipt operation both have homogeneous representations that are order preserving leads to a functional equation that has too many solutions to be useful for characterizing a reasonably specific utility representation. A plausible restriction on the form of the utility of gambles leads to the functional equation

     

中国城区青少年对广告价值的评价:前因和后果

通过对北京市7所中学366名学生的调查,探讨了青少年对广告价值的评价以及何种因素影响青少年对广告价值的评价,广告价值的评价是否会进一步影响其决策等问题。运用AMOS 4.0建立结构方程模型对研究假设进行检验,结果表明：（1）青少年对广告价值的评价直接影响到他们的决策意图;（2）在探讨广告价值的影响因素时发现,对广告的知觉因素（信息性和娱乐性）和青少年对广告以及广告商的社会认知（观看广告的社会动机和对广告劝服技巧的认识）对广告价值的影响作用也十分显著,信息性、娱乐性与社会动机都对广告价值产生积极影响,而对广告劝服技巧的认识则对广告价值产生显著的负面影响