Hearing by eye: how much spatial degradation can be tolerated?

In the McGurk effect (McGurk and MacDonald, 1976 Nature 264 746-748), illusory auditory perception is produced if the visual information from lip movements is discrepant from the auditory information from the voice. A study is reported of the tolerance of the effect to varying levels of spatial degradation (videotaped images of a speaker's face were quantised by a mosaic transform). The illusory effect systematically decreased with an increase in the coarseness of the spatial quantisation. However, even with the coarsest level (11.2 pixels/face) the illusion did not completely disappear. In addition, those participants who did not experience the illusion nevertheless showed the effects of auditory-visual interaction in their clarity ratings of the auditory stimulus. It is concluded that auditory-visual interaction in visible speech perception is based on relatively coarse-spatial-scale information.     

Different trends in perceptual pattern microgenesis as a function of the spatial range of local brightness averaging

Summary Stimulus patterns, quantized into small squares with the brightness level averaged within each square, were presented for recognition with various exposure durations. Qualitatively different recognition functions were obtained with varying spatial levels of quantization. The method used, if further elaborated, seems appropriate for the empirical differentiation between global and local levels of form and between integration and differentiation stages of a perceptual/attentional process.     

Wilson's disease in East Germany: in retrospect and perspectives -- an evaluation

Wilson's disease is an autosomal recessive inherited metabolic disorder due to a disturbance of copper metabolism. Although the primary genetic defect is not known a longlife treatment is necessary for establishing a negative copper balance by removing the metal of the abnormal body stores. Experiences in handling with this disease in our country over a period of 20 years are reported. Especially epidemiologic findings, the diagnostic procedures and the strategies in therapeutic regimes are discussed. Future advances in genomic diagnostics are mentioned.     

Visibility of Brief Images: The Dual-Process Approach

If successive, brief visual images are exposed for recognition or for psychophysical ratings, various effects and phenomena of fast dynamics of conscious perception such as mutual masking, metacontrast, proactive enhancement of contrast, proactive speed-up of the latency of subjective visual experience, the Fröhlich Effect, the Tandem Effect, attentional facilitation by visuospatial precuing, and some others have been found. The theory proposed to deal with these phenomena proceeds from the assumption that two types of brain processes are necessary in order to consciously recognize visual stimuli: (1) fast, specific processes of encoding that allocate and reactivate the stimulus representation which is based on the activity of selected cortical neurons and (2) relatively slower processes of facilitation of the activity of this specific representation that are mediated by the excitatory modulation of the EPSPs of those selected cortical neurons by the ascending input from nonspecific thalamus. Theperceptual retouchconstruct is proposed in order to characterize and analyze the interaction of (1) and (2). The neurophysiological characteristics of this bifunctional system of afference help to put forward several predictions that are found to be consistent with the empirical regularities of the above-described perceptual-attentional phenomena. These data form a body of converging evidence that is consistent with the predictions of the perceptual retouch approach.     

Social information in equine movement gestalts

One model of signal evolution is based on the notion that behaviours become increasingly detached from their original biological functions to obtain a communicative value. Selection may not always favour the evolution of such transitions, for instance, if signalling is costly due to predators usurping signal production. Here, we collected inertial movement sensing data recorded from multiple locations in free-ranging horses (Equus caballus), which we subjected to a machine learning algorithm to extract kinematic gestalt profiles. This yielded surprisingly rich and multi-layered sets of information. In particular, we were able to discriminate identity, breed, sex and some personality traits from the overall movement patterns of freely moving subjects. Our study suggests that, by attending to movement gestalts, domestic horses, and probably many other group-living animals, have access to rich social information passively but reliably made available by conspecifics, a finding that we discuss in relation with current signal evolution theories.     

Outcome evaluation in brief mother-infant psychotherapies: Report on 75 cases

The effects of brief mother–infant psychotherapies (maximum of 10 sessions) were examined in cases of functional and behavioral disturbances in children less than 30 months old. Seventy-five mother-infant dyads were assessed prior to treatment, at 1 week, and 6 months after therapy ended. The outcome measures were changes in the infant's symptoms, the behavioral interactions between mother and infant, and maternal representations. The effect of two forms of intervention—Psychodynamic Therapy and Interaction Guidance Therapy—were compared. Results indicated a significant symptom reduction; dyadic interactions became more harmonious (mothers became less intrusive and infants more cooperative). Maternal self-esteem grew significantly and negative affects decreased. Improvements lasted as least several months, with some positive improvement detected at the 6-month follow-up. No major difference in outcome was found between the effects of the two forms of intervention. Within the limitations of research in a clinical context, this study suggests that brief mother–infant psychotherapies are a cost-effective method of early intervention.     

Development, problems and results of specialty-specific genetic counseling at the Neurology Clinic of the Karl Marx University

Genetic counselling for inherited neurological diseases has been established at the Clinic for Neurology of Karl Marx University. Comprehensive experiences have been got with the specific and sometimes markedly different problems and aims of counselling in Wilsons disease, X-linked recessive muscular dystrophies, myotonic dystrophy and other neuromuscular disorders, Huntingtons chorea and hereditary ataxias.