The role of imagery-related properties in picture naming: A newly standardized set of 360 pictures for Japanese

Picture naming was investigated primarily to determine its dependence on certain imagery-related variables, with a secondary aim of developing a new set of Japanese norms for 360 pictures. Pictures refined from the original Nishimoto, Miyawaki, Ueda, Une, and Takahashi (Behavior Research Methods 37:398?C416, 2005) set were used. Naming behaviors were measured using four imagery-related measures (imageability, vividness, image agreement, and image variability) and four conventional measures (naming time, name agreement, familiarity, and age of acquisition), as well as a number of other measures (17 total). A simultaneous multiple regression analysis performed on naming times showed that the most reliable predictor was H, a measure of name diversity; two image-related measures (image agreement and vividness) and age of acquisition also contributed substantially to the prediction of naming times. The accuracy of picture naming (measured as name agreement) was predicted by vividness, age of acquisition, familiarity, and image agreement. This suggests that certain processes involving mental imagery play a role in picture naming. The full set of norms and pictures may be downloaded from http://www.psychonomic.org/archive/ or along with the article from http://www.springerlink.com.     

An experimental study of the second-signaling systems of man through the printed language

The author has published previously in this journal his findings that not only the sight of a “pickled plum” increased the resting saliva of Japanese adults, but the spoken words “pickled plum” also increased the amount of saliva as a natural conditional reflex. It was also found that the reflex was stronger when an oral interpretation of the words “pickled plum” was added to their mere phonation. The author deduced that language is a conditional stimulus, the concept of which is released by unconditional stimulation. In this paper the author experimentally shows that reading printed language as well as writing it has the same effect in the human.     

Possible worlds as shifting domains

Those who object to David Lewis' modal realism express qualms about philosophical respectability of the Lewisian notion of a possible world and its correlate notion of an inhabitant of a possible world. The resulting impression is that these two notions either stand together or fall together. I argue that the Lewisian notion of a possible world is otiose even for a good Lewisian modal realist, and that one can carry out a good Lewisian semantics for modal discourse without Lewisian possible worls. I do so by generalizing Lewis' own idea that restrictions on quantification come and go with the pragmatic wind and relativizing possible worlds as shifting domains of discourse. I then suggest a way to soften the infamous incredulous stare.     

A Map of Common Knowledge Logics

In order to capture the concept of common knowledge, various extensions of multi-modal epistemic logics, such as fixed-point ones and infinitary ones, have been proposed. Although we have now a good list of such proposed extensions, the relationships among them are still unclear. The purpose of this paper is to draw a map showing the relationships among them. In the propositional case, these extensions turn out to be all Kripke complete and can be comparable in a meaningful manner. F. Wolter showed that the predicate extension of the Halpern-Moses fixed-point type common knowledge logic is Kripke incomplete. However, if we go further to an infinitary extension, Kripke completeness would be recovered. Thus there is some gap in the predicate case. In drawing the map, we focus on what is happening around the gap in the predicate case. The map enables us to better understand the common knowledge logics as a whole.     

Spontaneous smile and spontaneous laugh: an intensive longitudinal case study

One male infant was observed from the day of his birth to the end of the 6th month. Total observation days were 171 days, and total observation time was 329 h 25 min and 35s. Five hundred and sixty-five spontaneous smiles and 15 spontaneous laughs (smiles accompanied by vocal sounds) were observed. Developmental psychologists have thought that spontaneous smiles integrate at about 3 months, but spontaneous smiles were recorded even in the 6th month. The percentage of bilateral smiles increased from the 2nd month. This is the first intensive longitudinal study on spontaneous smiles and spontaneous laughs.     

Entorhinal cortical Island cells regulate temporal association learning with long trace period

Temporal association learning (TAL) allows for the linkage of distinct, nonsynchronous events across a period of time. This function is driven by neural interactions in the entorhinal cortical–hippocampal network, especially the neural input from the pyramidal cells in layer III of medial entorhinal cortex (MECIII) to hippocampal CA1 is crucial for TAL. Successful TAL depends on the strength of event stimuli and the duration of the temporal gap between events. Whereas it has been demonstrated that the neural input from pyramidal cells in layer II of MEC, referred to as Island cells, to inhibitory neurons in dorsal hippocampal CA1 controls TAL when the strength of event stimuli is weak, it remains unknown whether Island cells regulate TAL with long trace periods as well. To understand the role of Island cells in regulating the duration of the learnable trace period in TAL, we used Pavlovian trace fear conditioning (TFC) with a 60-sec long trace period (long trace fear conditioning [L-TFC]) coupled with optogenetic and chemogenetic neural activity manipulations as well as cell type-specific neural ablation. We found that ablation of Island cells in MECII partially increases L-TFC performance. Chemogenetic manipulation of Island cells causes differential effectiveness in Island cell activity and leads to a circuit imbalance that disrupts L-TFC. However, optogenetic terminal inhibition of Island cell input to dorsal hippocampal CA1 during the temporal association period allows for long trace intervals to be learned in TFC. These results demonstrate that Island cells have a critical role in regulating the duration of time bridgeable between associated events in TAL.

The linkage of temporally discontiguous events, called temporal association learning (TAL), is an essential function for episodic memory formation; for animals, when an event took place, and in what order a series of events occurred is directly linked to adaptation to continuous changes in the environment (Eichenbaum 2000; Tulving 2002a,b; Kitamura et al. 2015a; Kitamura 2017; Pilkiw and Takehara-Nishiuchi 2018). The entorhinal cortical–hippocampal (EC-HPC) network in particular is currently considered to bridge the temporal discontinuity between events (Solomon et al. 1986; Moyer et al. 1990; Wallenstein et al. 1998; McEchron et al. 1999; Eichenbaum 2000; Huerta et al. 2000; Ryou et al. 2001; Takehara et al. 2003; Chowdhury et al. 2005; Esclassan et al. 2009; Morrissey et al. 2012; Suter et al. 2013; Sellami et al. 2017; Wilmot et al. 2019).Two major excitatory inputs to HPC arise from the superficial layers of the EC (Fig. 1A), forming the direct (monosynaptic), and indirect (trisynaptic) pathways (Amaral and Witter 1989; Amaral and Lavenex 2007; Kitamura 2017; Kitamura et al. 2017). While pyramidal cells in EC layer III (ECIII cells) project directly to CA1 (Kohara et al. 2014; Kitamura et al. 2015b), the trisynaptic pathway originates from excitatory Reelin⁺ stellate cells in EC layer II (ECII) projecting directly to DG, CA3, and CA2 (Fig. 1B; Tamamaki and Nojyo 1993; Varga et al. 2010). CalbindinD-28K⁺/Wolfram syndrome 1 (Wfs1)⁺ pyramidal cells, another excitatory neural population in EC layer II called “Island cells,” form cell clusters along the ECII/ECI border (Alonso and Klink 1993; Fujimaru and Kosaka 1996; Klink and Alonso 1997; Kawano et al. 2009; Varga et al. 2010; Kitamura et al. 2014; Ray et al. 2014) and directly project to the GABAergic interneurons of stratum lacunosum (SL-INs) in HPC CA1 and drive feedforward inhibition to HPC CA1 pyramidal cells (Fig. 1B; Kitamura et al. 2014; Surmeli et al. 2016; Kitamura 2017; Ohara et al. 2018; Yang et al. 2018; Zutshi et al. 2018).Open in a separate windowFigure 1.Circuit schematic diagram of the medial entorhinal cortex (MEC)–hippocampal (HPC) circuit. (A) Major projections in the entorhinal cortical (EC)-HPC network. ECIII neurons (green) project directly to CA1. ECII Ocean cells (ECIIo, purple) project to the dentate gyrus (DG) (light blue)/CA3 (pink) initiating the trisynaptic pathway. ECII Island cells (ECIIi, blue) project directly into CA1. (B) ECIII projections (green) excite the distal portions of CA1 pyramidal cell (yellow) dendrites in the stratum moleculare. Island cells (ECIIi, blue) excite the interneurons of stratum lacunosum (SL-INs, red), which in turn inhibit the distal dendrites of CA1 pyramidal cells in SL.Trace fear conditioning (TFC) has been established as one suitable animal model for TAL (Fendt and Fanselow 1999; Maren 2001; Kim and Jung 2006) that can be also used as a translational bridge between animal and human learning (Clark and Squire 1998; Buchel and Dolan 2000; Delgado et al. 2006). Lesion, pharmacological, molecular, and optogenetic manipulation, as well as disease models in medial entorhinal cortex (MEC), demonstrate that MEC is crucial for TFC and temporal learning (Ryou et al. 2001; Woodruff-Pak 2001; Runyan et al. 2004; Esclassan et al. 2009; Gilmartin and Helmstetter 2010; Suh et al. 2011; Morrissey et al. 2012; Shu et al. 2016; Hales et al. 2018; Yang et al. 2018; Heys et al. 2020). Specifically, MECIII inputs into the HPC CA1 pyramidal cells are essential for the formation of TFC (Yoshida et al. 2008; Suh et al. 2011; Kitamura et al. 2014; Kitamura 2017). However, the temporal association function driven by MECIII neurons must be regulated for optimal adaptive memory formation, as too strong an association of a particular pair of events may interfere with associations of other useful pairs, whereas too weak an association for a given pair of events, in terms of weaker impact of events or longer duration of temporal gap between events, would not result in an effective memory (Kitamura et al. 2015a; Marks et al. 2020). In a naturalistic context, this would mean that more distant/quieter sounds, less intense somatic sensations (e.g., pain), or increased temporal distance between any two events would signal that the events are less likely to be causally associated, therefore less relevant, and less likely to be stored and recalled. In fact, successful TFC depends on the strength of event stimuli and duration of temporal gap between events (Stiedl and Spiess 1997; Misane et al. 2005; Kitamura et al. 2014; Kitamura 2017). However, the underlying regulatory mechanism for TAL remains hidden. Previously we demonstrated that feedforward inhibition by Island cells acts as a gating controller for the MECIII inputs to the distal dendrites of HPC CA1 pyramidal cells in stratum moleculare (SM) (Kitamura et al. 2014) to control TFC when weaker (in this case diminished footshock intensity) unconditioned stimuli were delivered for TFC, indicating that Island cell activity controls the temporal association when the strength of two discontinuous events are relatively weaker. However, the way in which the EC-HPC network regulates TFC with a longer trace period still remains unknown. Because the activation of Island cells would result in a net inhibitory effect on the local network in CA1, imposing a tight and specific regulation on associations of events across the temporal gap in TAL (Crestani et al. 2002; Moore et al. 2010; Kitamura et al. 2014, 2015b), we hypothesized that the length of the temporal gap between events would also be modulated by this mechanism. In this study, we examined the role of the regulatory input to this circuit arising specifically from the Island cells in the MECII using apoptotic elimination of Island cells, chemogenetic neural inhibition, and optogenetic terminal inhibition methods within an L-TFC protocol to give a thorough and complete assessment of the circuit involvement while considering each technique''s unique features.     

The effect of a protagonist’s emotional shift on situation model construction

We examined whether readers monitored protagonists' emotional shifts and whether reader engagement influenced situation model construction. Participants read narratives that included an emotional shift in the middle of the story. In Experiment 1, participants were instructed to read stories appreciatively and to empathize with the protagonists. In Experiment 2, readers were instructed to read the stories normally, as if they were reading novels. The results from the two experiments suggest that readers monitor temporal and causal shifts as well as protagonists' emotional shifts in stories. Moreover, in Experiment 1 readers detected temporal and causal shifts regardless of th e degree oftheir engagement during the empathetic reading, while in Experiment 2 the high ego involvement group detected causal shifts during the normal reading. Thus, these results show both that readers monitor protagonists' emotional states and that reader emotional engagement c an influence situationmodel construction with normal reading.     

Preserved ability to recognize keywords related to remote events in the absence of retrieval of relevant knowledge: a case of postencephalitic amnesia

We describe a case of severe anterograde and retrograde amnesia resulting from herpes simplex encephalitis. Magnetic resonance imaging revealed pathological changes in the bilateral hippocampi, parahippocampal gyri, fusiform gyri, medial temporal poles, posterior part of the cingulate gyri, and insula. The patient showed severe amnesia for autobiographical episodic memory in relation to events that had occurred throughout her life, but temporally graded amnesia for autobiographical semantic memory, and severe amnesia without a temporal gradient for public events and famous people. However, using a multiple-choice method, she showed a high level of accuracy when choosing keywords related to public or personal events, although this did not prompt her recollection of the events. An important indication of these results is that, even with severe retrograde amnesia, memories of past events are not completely lost. We propose that an event may be stored in a fragmented form, consisting of many components, and that normal recall of an event may require recombination or reconstruction of these components.     

Affective integration speeds trait processing

We investigated whether affective integration increases the speed of processing of personality trait knowledge. The fan effect was compared between cases where trait knowledge is stored with the affective value and cases where it is not stored with the affective value. 18 college students first memorized a set of traits about fictitious individuals and then made recognition judgments. In the 2 x 2 factorial repeated-measures design, the number of traits learned about a fictitious individual and whether those traits were integrated by a shared affective value were manipulated. The significant interaction showed that knowledge of personality trait with affective integration was processed quickly even if the particular person's memory had rich connections with traits.     

Preference modulates smelling behaviour in olfactory decision tasks

When people are shown a pair of images and asked to identify which one is more attractive, their gaze shifts to the image they will eventually choose, prior to making the decision. Many researchers have examined the relationship between this gaze bias and decision processes, but not the relationships between other sensory modalities and decision processes. This study examined behaviour in relation to olfactory decision tasks. In accordance with the concept of gaze bias, the likelihood of participants smelling the item they eventually chose immediately before the decision was greater when they were instructed to identify an item that was more, versus less, favoured. The likelihood of smelling the item that was eventually chosen last was also greater than chance when participants were instructed to identify the more masculine item. These results suggest that a bias to sample a chosen item last is a common phenomenon regardless of sensory modality.