活性蛋白C:想说爱你不容易

重组人类活性蛋白C(rhAPC)为治疗重症脓毒症的药物,目前有证据表明rhAPC的市场策略有可能已经影响到专业机构诊治指南的制定与执行;rhAPC的临床疗效亦未能被大型临床试验继续证实,因此目前rhAPC的临床应用以及疗效评价要慎重进行.同时,有必要深入反思药品生产商与专业组织的利益关系,并制订对策以加强监管.     

Contextualized personality: traditional and new assessment procedures

We describe our ongoing program of research related to the assessment of contextualized personality, focusing on social roles and cultural cues as contextual factors. First, we present our research employing the traditional assessment approach, wherein participants are asked to rate explicitly their personality across several different roles. We argue that this hypothetical approach is potentially susceptible to the influence of stereotypes, social desirability, and demand characteristics. We therefore describe the development of three novel and subtle assessment procedures that are based on obtaining online self-representations that are activated while occupying a specific context. Finally, the strengths and limitations of all four approaches, as well as directions for future research in the study of contextualized personality, are discussed.     

数学文化与儿童数学认知

数学文化以文化为视角.在人类文化发展的历史过程中审视和理解数学,为我们认识和理解儿童数学认知开辟了全新的方向.作为数学文化的重要内容的数学信念、数学价值观、数学典故、数学符号、数学法则以及实物工具等,在儿童数学认知的知识提取、理解与表征、记忆与策略、认知风格、情绪态度以及自我效能等方面起着重要的影响作用.     

“国际逻辑会议LOGIC2009”会议综述

由贵州大学计算机科学与信息学院主办的“国际逻辑会议LOGIC2009”于2009年9月22日在贵州大学南校区南园接待中心隆重召开。20多位逻辑学家、数学家和计算机科学家参加了会议,他们分别来自贵州大学、贵州民族学院、新加坡国立大学、中国科学院、北京师范大学、四川大学、南开大学、南京大学、     

Abusive supervision, intentions to quit, and employees’ workplace deviance: A power/dependence analysis

We conducted a two-study examination of relationships between abusive supervision and subordinates’ workplace deviance. Consistent with predictions derived from power/dependence theory, the results of a cross-sectional study with employees from three organizations suggest that abusive supervision is more strongly associated with subordinates’ organization deviance and supervisor-directed deviance when subordinates’ intention to quit is higher. The results also support the prediction that when intention to quit is higher, abusive supervision is more strongly associated with supervisor-directed deviance than with organization-directed deviance. These results were replicated in a second study, a two-wave investigation of people employed in a variety of industries and occupations.     

中文句子阅读中语义信息对眼动预视效应的影响

采用句子为阅读材料,变化句子中一个单字词形成语义连贯与语义违背两种实验条件,通过两个眼动实验探讨中文句子阅读中预视效应的产生是否受语义信息的影响。实验一运用自然阅读范式,考察当语义连贯与违背两类信息被读者直接注视时,读者眼动模式的变化。结果发现,在语义连贯与违背两种条件下,读者的眼动模式在目标位置立即产生差异,违背条件下首次注视时间更长,说明中文句子理解中语义加工可以进行得十分即时。实验二运用边界技术,使实验一的语义连贯与违背两类关键字只呈现在预视位置上,当读者的注视点越过边界时,两类预视字均变为另一个与句子意义连贯的目标字。结果发现,语义违背预视条件下,读者对预视位置将进行更长时间的加工。上述结果表明,中文句子阅读过程中,语义信息可以对预视效应产生影响     

再生障碍性贫血发病机制认识的发展与启示

再生障碍性贫血的发病机制已经突破了“种子”、“土壤”、“虫子”学说,并沿着“免疫异常”理论进入“自身免疫病”理论。同时这是一个科学思维付诸实践不断探索的过程。大量证据表明再生障碍性贫血是一种自身免疫病,它应该符合自身免疫病的共性,这一认识开阔了人们的视野,使人们能在更高的层面上考察原来的事物。     

盐酸戊乙奎醚对心脏瓣膜置换术患者NF-κB表达的影响

为研究盐酸戊乙奎醚对心脏瓣膜置换术患者心肌NF-κB转录活性的影响,选取择期瓣膜置换术患者60例,随机分为对照组（C）、盐酸戊乙奎醚组1（P1）、盐酸戊乙奎醚组2（P2）,每组20例。结果心肌缺血再灌注后,P1、P2组NF-κB的转录活性明显下降,可见盐酸戊乙奎醚可以抑制心肌NF-κB的激活,在一定程度上具有心肌保护作用。     

腹内脂肪与胰岛素抵抗

腹内脂肪与胰岛素抵抗的关系密切,它在形态、脂解等方面不同于皮下脂肪.脂肪细胞分泌的细胞因子在胰岛素抵抗的发生发展中有着重要的作用.明确腹内脂肪致胰岛素抵抗的机制有益于代谢综合征的防治.     

细菌耐药性的产生及预防对策

细菌耐药性的产生是当今医学界所普遍面临的严重问题,危害着人类的健康和生存.通过透析细菌耐药的根源和机制,使人们认清细菌耐药性问题的实质,为制定出合理使用抗菌药物的原则和预防细菌耐药性的措施提供一些理论依据.