从胡塞尔思想发展看他的观念论的含义

我们知道,胡塞尔在1908年前后向先验观念论的转变使他的学生们深受震动。人们认为,这是他否定自己早期的实在论,而集中研究对象。在这一点上,哥廷根时期的许多(如果不是全部的话)弟子都对这位大师困惑不解。然而奇怪的是,尽管弗莱堡时期的那些后期弟子们也反对他的观念论,但恰恰是他们,诸如海德格尔、芬克、兰德格雷勃和     

Gami-Chunghyuldan ameliorates memory impairment and neurodegeneration induced by intrahippocampal Aβ 1-42 oligomer injection

Soluble oligomeric forms of amyloid beta (AβO) are regarded as a main cause of synaptic and cognitive dysfunction in Alzheimer’s disease (AD) and have been a primary target in the development of drug treatments for AD. The present study utilized a mouse model of AD induced by intrahippocampal injection of AβO (10 μM) to investigate the effects of Gami-Chunghyuldan (GCD), a standardized multi-herbal medicinal formula, on the presentation of memory deficits and neurohistological pathogenesis. GCD (10 and 50 mg/kg/day, 5 days, p.o.) improved AβO-induced memory impairment as well as reduced neuronal cell death, astrogliosis, and microgliosis in the hippocampus. In addition, GCD prevented AβO-triggered synaptic disruption and cholinergic fiber loss. These results suggest that GCD may be useful in the prevention and treatment of AD.     

Methodological challenges in union commitment studies

Methodological problems in studies of union commitment were identified and illustrated with data from 4,641 members and 479 stewards in 297 local teachers' unions. Using a 20-item union commitment scale, results confirmed the existence of 3 substantive factors and 1 method factor at the individual level of analysis: loyalty to the union, responsibility to the union, willingness to work for the union, and a factor of negatively worded items. Tests of measurement invariance showed that the scale captured commitment for rank-and-file members but not for union stewards. The authors also found partial measurement invariance between long-time and newer members and full measurement invariance between men and women. Finally, the authors found that violation of the statistical assumption of independence reduced model fit when individual commitment scores were analyzed without attention to the hierarchical nature of the data.     

Crewmember performance before, during, and after spaceflight

The development of technologies for monitoring the welfare of crewmembers is a critical requirement for extended spaceflight. Behavior analytic methodologies provide a framework for studying the performance of individuals and groups, and brief computerized tests have been used successfully to examine the impairing effects of sleep, drug, and nutrition manipulations on human behavior. The purpose of the present study was to evaluate the feasibility and sensitivity of repeated performance testing during spaceflight. Four National Aeronautics and Space Administration crewmembers were trained to complete computerized questionnaires and performance tasks at repeated regular intervals before and after a 10-day shuttle mission and at times that interfered minimally with other mission activities during spaceflight. Two types of performance, Digit-Symbol Substitution trial completion rates and response times during the most complex Number Recognition trials, were altered slightly during spaceflight. All other dimensions of the performance tasks remained essentially unchanged over the course of the study. Verbal ratings of Fatigue increased slightly during spaceflight and decreased during the postflight test sessions. Arousal ratings increased during spaceflight and decreased postflight. No other consistent changes in rating-scale measures were observed over the course of the study. Crewmembers completed all mission requirements in an efficient manner with no indication of clinically significant behavioral impairment during the 10-day spaceflight. These results support the feasibility and utility of computerized task performances and questionnaire rating scales for repeated measurement of behavior during spaceflight.     

More on the fragility of performance: choking under pressure in mathematical problem solving

In 3 experiments, the authors examined mathematical problem solving performance under pressure. In Experiment 1, pressure harmed performance on only unpracticed problems with heavy working memory demands. In Experiment 2, such high-demand problems were practiced until their answers were directly retrieved from memory. This eliminated choking under pressure. Experiment 3 dissociated practice on particular problems from practice on the solution algorithm by imposing a high-pressure test on problems practiced 1, 2, or 50 times each. Infrequently practiced high-demand problems were still performed poorly under pressure, whereas problems practiced 50 times each were not. These findings support distraction theories of choking in math, which contrasts with considerable evidence for explicit monitoring theories of choking in sensorimotor skills. This contrast suggests a skill taxonomy based on real-time control structures.     

Childhood maltreatment associated with adult personality disorders: findings from the Collaborative Longitudinal Personality Disorders Study

Adverse childhood experiences such as abuse and neglect are frequently implicated in the development of personality disorders (PDs); however, research on the childhood histories of most PD groups remains limited. In this multisite investigation, we assessed self-reported history of abuse and neglect experiences among 600 patients diagnosed with either a PD (borderline, schizotypal, avoidant, or obsessive-compulsive) or major depressive disorder without PD. Results indicate that rates of childhood maltreatment among individuals with PDs are generally high (73% reporting abuse; 82% reporting neglect). As expected, borderline PD was more consistently associated with childhood abuse and neglect than other PD diagnoses. However, even when controlling for the effect of borderline PD, other PD diagnoses were associated with specific types of maltreatment.     

Tasks of a feather flock together: Similarity effects in task switching

Recent research on task switching has paid little attention to how tasks are represented and how the relations between task representations might affect the executive processes engaged to achieve a task switch. Two experiments investigated the effect of task similarity on task switching. Similarity was defined in terms of shared component operations--attentional control settings in Experiment 1 and response modality in Experiment 2--with tasks sharing more component operations said to be more similar to each other than tasks sharing fewer component operations. Across both experiments, task similarity facilitated task switching, seen in reduced switch costs for switching between similar tasks as opposed to dissimilar tasks. These results indicate that task similarity defined in terms of component operations can be used to define a multidimensional task space in which the executive processes of task selection and implementation are active.     

Axis I and axis II disorders as predictors of prospective suicide attempts: findings from the collaborative longitudinal personality disorders study

This study examined diagnostic predictors of prospectively observed suicide attempts in a personality disorder (PD) sample. During 2 years of follow-up, 58 participants (9%) reported at least 1 definitive suicide attempt. Predictors that were examined include 4 PD diagnoses and selected Axis I diagnoses (baseline and course). Multivariate logistic regression analyses indicated that baseline borderline personality disorder (BPD) and drug use disorders significantly predicted prospective suicide attempts. Controlling for baseline BPD diagnosis, proportional hazards analyses showed that worsening in the course of major depressive disorder (MDD) and of substance use disorders in the month preceding the attempt were also significant predictors. Therefore, among individuals diagnosed with PDs. exacerbation of Axis I conditions, particularly MDD and substance use, heightens risk for a suicide attempt.