Perinatal maternal undernutrition programs the offspring hypothalamo-pituitary-adrenal (HPA) axis

There is now compelling evidence, coming both from animal and human studies that an early exposure to undernutrition is frequently associated with low birth weight and programs HPA axis alterations throughout the lifespan. Although animal models have reported conflicting findings arising from differences in experimental paradigms and species, they have clearly demonstrated that such programming not only affects the brain but also the pituitary corticotrophs and the adrenal cortex. In fetuses, maternal undernutrition reduces HPA axis function and implicates a reduction of placental 11beta-HSD2 activity and a greater transplacental transfer of glucocorticoids (GRs). In young adults, usually only fine HPA axis alterations were observed, whereas in older ones, maternal undernutrition was frequently associated with chronic hyperactivity of this neuroendocrine axis. In humans, evidence of HPA axis dysregulation in people who were small at birth has recently emerged. Thus, we suggest that such alterations in adults may be implicated in the aetiology of several disorders related to the metabolic syndrome as well as to immune or inflammatory diseases. To reverse such programming, recent experimental reports have shown that postnatal environmental interventions, dietary modifications and the use of agents modulating the epigenomic state could partly restore physiological functions and thus open new therapeutic strategies.     

Mere exposure effect: A consequence of direct and indirect fluency-preference links

In three experiments, picture quality between test items was manipulated to examine whether subjects' expectations about the fluency normally associated with these different stimuli might influence the effects of fluency on preference or familiarity-based recognition responses. The results showed that fluency due to pre-exposure influenced responses less when objects were presented with high picture quality, suggesting that attributions of fluency to preference and familiarity are adjusted according to expectations about the different test pictures. However, this expectations influence depended on subjects' awareness of these different quality levels. Indeed, imperceptible differences seemed not to induce expectations about the test item fluency. In this context, fluency due to both picture quality and pre-exposure influenced direct responses. Conversely, obvious, and noticed, differences in test picture quality did no affect responses, suggesting that expectations moderated attributions of fluency only when fluency normally associated with these different stimuli was perceptible but difficult to assess.     

Executive functioning in normal aging: a study of action planning using the Zoo Map Test

A particularly important aspect of executive functioning involves the ability to form and carry out complex plans, that is to say planning. This study aimed to investigate planning in 18 older and 16 younger normal participants using an ecological planning subtask derived from the Behavioural Assessment of the Dysexecutive Syndrome test battery, the "Zoo Map Test." There are two trials. The first trial consists of a "high demand" version of the subtask in which the participants must plan in advance the order in which they will visit designated locations in a zoo (formulation level). In the second, or "low demand" version, the participant is simply required to follow a concrete externally imposed strategy to reach the locations to visit (execution level). The two-way ANOVAs mainly showed more difficulties in elderly adults than in younger adults, more difficulties in formulation level than in execution level, and lastly a greater difference between formulation and execution in older participants than in younger adults. These results suggest that elderly participants have some problems developing logical strategies whereas they are able to execute complex predetermined plans.     

Psycholinguistic norms for action photographs in French and their relationships with spoken and written latencies

A set of 142 photographs of actions (taken from Fiez & Tranel, 1997) was standardized in French on name agreement, image agreement, conceptual familiarity, visual complexity, imageability, age of acquisition, and duration of the depicted actions. Objective word frequency measures were provided for the infinitive modal forms of the verbs and for the cumulative frequency of the verbal forms associated with the photographs. Statistics on the variables collected for action items were provided and compared with the statistics on the same variables collected for object items. The relationships between these variables were analyzed, and certain comparisons between the current database and other similar published databases of pictures of actions are reported. Spoken and written naming latencies were also collected for the photographs of actions, and multiple regression analyses revealed that name agreement, image agreement, and age of acquisition are the major determinants of action naming speed. Finally, certain analyses were performed to compare object and action naming times. The norms and the spoken and written naming latencies corresponding to the pictures are available on the Internet (http://www.psy.univ-bpclermont.fr/~pbonin/pbonin-eng.html) and should be of great use to researchers interested in the processing of actions.     

Evaluating the coordination dynamics of handwriting

This study aims to test the hypothesis that handwriting is governed by the dynamics of non-linear coupled oscillators. Accordingly, its first goal is to identify preferred, basic graphic shapes corresponding to spontaneously stable combinations of the two frequency-locked oscillatory x-y components of the trajectories. Six participants were required to produce 26 ellipsoids of varying eccentricities and orientations presented consecutively on a graphic tablet. These shapes corresponded to a systematic manipulation of the relative phase and the relative amplitude of the oscillators by a constant step. Results showed that among those, only eight ellipsoids were produced in a spontaneous and stable fashion. They were characterized by attraction of nearby shapes, and by a higher accuracy and velocity. Alike all periodic motion, graphic skills, hence handwriting, exhibit preferred coordination patterns, which can be ascribed to the non-linear coupling of two oscillators.     

Evening and morning EEG differences between young men and women adults

Evening and morning waking EEG (eyes closed) was recorded in 16 women and 13 men aged 18-26 years old. Participants were fitted with a 13-electrode montage (Fp1, Fp2, FZ, F7, F8, C3, C4, T3, T4, P3, P4, O1, and O2) referred to linked ears. For each recording electrode, EEG total spectral amplitude power (microV/Hz, 0.75-19.75 Hz) was compared using 2 (Gender) x 2 (Moments) analyses of variance for repeated measures and LSD post-hoc tests. We found significant simple Gender effects, with women displaying higher EEG values for Central, Frontal, Parietal, and left Temporal leads. Simple Moment effects were also found, with lower morning values in Temporal and left Frontal recording sites. A Gender x Moment interaction was found at the right Frontal recording site. No significant effects were found for Prefrontal and Occipital recording sites, whatsoever. These results bring new understandings of gender and time of day effects in waking EEG and point to different sensitivity in different cortical areas. The present results could explain some of the observations related to gender differences in cognitive performance.     

Selective attention, inhibition for repeated events and hemispheric specialization

When two visual events appear consecutively in the same spatial location, our response to the second event is slower than to the first. This inhibition for repeated events may reflect a bias toward sampling novel locations, a bias useful for exploring visual space. It has been shown that the left hemisphere is more specialized in selective attentional processes than the right one. The aim of the present experiment was to test if this hemispheric specialization for selective attention may also affect the inhibition for repeated events. For this purpose, we asked 11 normal subjects to perform an identity-based discrimination task in which the target to be detected could appear alone or surrounded by flanking letters, in the left or in the right visual field. Results show that inhibition for repeated events is present only when selective attention is required and when the task is performed in the right specialized visual field.     

Hemispheric specialization for spatial frequency processing in the analysis of natural scenes

Experimental data coming from visual cognitive sciences suggest that visual analysis starts with a parallel extraction of different visual attributes at different scales/frequencies. Neuropsychological and functional imagery data have suggested that each hemisphere (at the level of temporo-parietal junctions-TPJ) could play a key role in spatial frequency processing: The right TPJ should predominantly be involved in low spatial frequency (LFs) analysis and the left TPJ in high spatial frequency (HFs) analysis. Nevertheless, this functional hypothesis had been inferred from data obtained when using the hierarchical form paradigm, without any explicit spatial frequency manipulation per se. The aims of this research are (i) to investigate, in healthy subjects, the hemispheric asymmetry hypothesis with an explicit manipulation of spatial frequencies of natural scenes and (ii) to examine whether the 'precedence effect' (the relative rapidity of LFs and HFs processing) depends on the visual field of scene presentation or not. For this purpose, participants were to identify either non-filtered or LFs and HFs filtered target scene displayed either in the left, central, or right visual field. Results showed a hemispheric specialization for spatial frequency processing and different 'precedence effects' depending on the visual field of presentation.     

Monoparentalité et santé: Problèmes de santé et mobilisation de ressources d'assistance suite à la désunion

A partir d'une enquête auprès d'un échantillon représentatif de chefs de foyers monoparentaux québécois, le présent article étudie les interrelations entre les problèmes de santé vécus par les membres de l'unité familiale, la mobilisation des ressources d'assistance et la perception qu'ont les parents gardiens du réseau de la santé, ainsi que de l'aide étatique qui leur est dispensée. La mésentente parentale au moment de la rupture est associée aux problèmes psychologiques vécus par le parent gardien et les enfants, et pourrait engendrer des problèmes pour lesquels les parents ne trouvent pas réponse dans les réseaux formels d'assistance. Les parents qui ont peu bénéficié de l'aide des réseaux informels se montrent plus critiques vis-à-vis de l'assistance de l'État. Des comparaisons sont effectuées selon le sexe et la langue d'usage du parent gardien.     

Six Years in the Cognitive and Metacognitive Life of 71 Families

Seventy-one families from a low socio-economic background, each with a son at risk of developing psychosocial problems at the onset of the study, were observed three times over a six-year period while solving a combinatorial task presented on a microcomputer. The permutations task was used to gather information with regard to cognitive functioning and cognitive self-regulation of the families, which were observed as a developmental unit. Cognitive functioning was assessed according to three variables: cognitive strategies, performance, and completion of the task. Six self-regulatory activities were assessed: task definition, planning, supervision, evaluation, parental support, and sharing of responsibilities. Although inefficient strategies were mainly used across the six years, the cognitive level of functioning improved over the years. Cognitive self-regulatory activities most often used across time were supervision and parental support. Differences were observed in the three time periods for supervision, task definition, parental support, and individual involvement. Results indicated a link between cognitive strategies used by the families to solve the task and their self-regulatory activities. Results are interpreted within both the Piagetian and Vygotskian perspectives. Families' cognitive self-regulatory activities observed in this study are an example of parental disengagement and children's growing involvement in a joint activity.