Visuospatial working memory in school-aged children exposed in utero to cocaine.

OBJECTIVE: Among the neurocognitive impairments reported as associated with prenatal cocaine exposure, slower response time, and less efficient learning in school-aged children are common to findings from several laboratories. This study presents performance data on a spatial working memory task in 75 prenatally cocaine exposed (CE) and 55 nondrug-exposed (NDE) 8- to 10-year-old children. METHODS: Children were administered a novel neuropsychological measure of immediate- and short-term memory for visuospatial information, the Groton Maze Learning Test (GMLT), a computer-based hidden maze learning test that consists of a "timed chase test" (a simple measure of visuomotor speed), eight learning trials followed by a delayed recall trial after an 8-minute delay and a reverse learning trial. Performance is expressed as correct moves per second and number of errors per trial. RESULTS: Across all trials, the cocaine-exposed group showed significantly slower correct moves per second and made significantly more errors. There were no significant main effects for amounts of alcohol, tobacco, or marijuana exposure. After an 8-minute delay and compared to the eighth trial, cocaine-exposed children showed less consolidation in learning compared to nonexposed children. When asked to complete the maze in reverse, cocaine-exposed children showed a greater decrement in performance (decreased correct moves per second and increased errors) compared to the eighth learning trial. CONCLUSIONS: Children exposed in utero to cocaine exhibit a possible impairment in procedural learning and diminished efficiency in creating and accessing an internal spatial map to master the hidden maze.     

Improving health outcomes among youth with poorly controlled type I diabetes: the role of treatment fidelity in a randomized clinical trial of multisystemic therapy.

The purpose of the study was to assess whether therapist treatment fidelity was a predictor of treatment outcome in a randomized clinical trial of multisystemic therapy with 10- to 16-year-old youths with chronically poorly controlled Type I diabetes (N = 40). Treatment fidelity was assessed by objective ratings of therapy sessions and questionnaires completed by caregivers and by therapists. Relationships between fidelity measures were assessed. Structural equation modeling (SEM) was used to test whether high fidelity would lead to improved regimen adherence and to improved metabolic control outcomes via regimen adherence. Objective ratings of treatment fidelity were significantly related to therapist-reported but not to caregiver-reported treatment fidelity. SEM results supported a completely mediated pathway between treatment fidelity and metabolic control, with regimen adherence mediating the relationship. Results suggest that conducting complex behavioral interventions with a high degree of fidelity can improve treatment outcomes among youths with chronic illnesses.     

Anger and time perception in children

The present study investigated age-related variations in judgments of the duration of angry facial expressions compared with neutral facial expressions. Children aged 3, 5, and 8 years were tested on a temporal bisection task using angry and neutral female faces. Results revealed that, in all age groups, children judged the duration of angry faces to be longer than that of neutral faces. Findings are discussed in the framework of internal clock models and the adaptive function of emotion.     

Inhibitory Control Deficits in Individuals with Amnestic Mild Cognitive Impairment: a Meta-Analysis

Neuropsychology Review - Amnestic mild cognitive impairment (aMCI) is a prodromal stage of Alzheimer’s disease that is characterized by impairments in episodic memory. Recent evidence has...     

Evidence for Early closure Attachment on First pass Reading Times in French

An eye-tracking experiment was conducted in French with sentences of the form 'N V N1of-N2 who . . . ' Example: 'A journalist approachedthe barrister (male) of the singer (female) who seemed more confident (masculine or feminine gender) than (s)he ought to be.' The results are consistentwiththose of Cuetos and Mitchell(1988).French readers,like Spanish readers, prefer early closure (and are garden-pathed when the sentence turns out to be a late-closure attachment). This effect was exhibited by first-pass reading times that are usually assumed to reflect initial syntactic commitments. These results are discussed in relation to Frazier and Clifton's recent proposals concerning attachment mechanisms in the case of 'non-primary' relationships such as relative clauses, and more precisely the notion that early-closure attachments observed in cross-linguistic studies are determined by relatively late processes.     

Breast cancer: The intention to have a mammography and a clinical breast examination - application of the theory of planned behavior

Abstract

The purpose of these cross sectional studies was to identify the psychosocial factors explaining women's intention to have a mammography within the next two years and their intention to have a clinical breast examination (CBE) by a professional within the next year. Two random samples of women aged 40–69 years (n_a = 354, n_b = 344) completed a self-administered questionnaire that investigated theoretical constructs of the theory of planned behavior. The results of structural equation modeling showed that subjective norms and perceived behavioral control explained 81 % of the variance in intention of having a mammography. Sixty-five percent (65%) of the variance in intention of having a CBE was explained by attitude and perceived behavioral control. In conclusion, women need to be better informed, have better skills to overcome psychological and physical barriers in performing preventive breast behaviors, and promotion of preventive breast cancer methods should consider people significant for women.     

The Balance-Scale Dilemma: Either the Subject or the Experimenter Muddles Through

We examined two critiques of rule-assessment methodology: (a) the method does not take into consideration other rules that subjects use to solve problems, and (b) its multiple-choice format misrepresents subjects' cognitive level. In Study 1, high school students completed a paper-and-pencil, multiple-choice balance scale questionnaire. Their performance was assessed with Siegler's original rules and a revised set of rules that included an addition and a qualitative proportionality rule. Results showed that Siegler's Rule 3 was not homogeneous and that distinguishing specific patterns of answers among Rule 3 subjects increased the diagnostic value of the rule-assessment methodology. In Study 2, we compared rule-assessment methodology to the Piagetian clinical model. High school students solved balance-scale problems within each method. Results indicated an overall match between Piagetian levels and Siegler's rules, with the exception of Rule 3, suggesting again the pertinence of specifying alternative rules.