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The striatum plays a critical role in learning from reward, and it has been implicated in learning from performance-related feedback as well. Positive and negative performance-related feedback is known to engage the striatum during learning by eliciting a response similar to the reinforcement signal for extrinsic rewards and punishments. Feedback is an important tool used to teach new skills and promote healthful lifestyle changes, so it is important to understand how motivational contexts can modulate its effectiveness at promoting learning. While it is known that striatal responses scale with subjective factors influencing the desirability of rewards, it is less clear how expectations and goals might modulate the striatal responses to cognitive feedback during learning. We used functional magnetic resonance imaging to investigate the effects of task difficulty expectations and achievement goals on feedback processing during learning. We found that individuals who scored high in normative goals, which reflect a desire to outperform other students academically, showed the strongest effects of our manipulation. High levels of normative goals were associated with greater performance gains and exaggerated striatal sensitivity to positive versus negative feedback during blocks that were expected to be more difficult. Our findings suggest that normative goals may enhance performance when difficulty expectations are high, while at the same time modulating the subjective value of feedback as processed in the striatum.  相似文献   
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George V. Coyne  SJ 《Zygon》2013,48(1):221-229
Abstract Although Galileo's venture into theology, as discussed by McMullin, is limited to Galileo's exegesis of Scripture, it can be seen as an important element in a broader role in theology, namely in ecclesiology and in the development of doctrine. From the Council of Trent, the Reformation Council, until today there has been a development in the Church concerning the manner in which Sacred Scripture should be interpreted and as to whether it can be said to be in conflict with our scientific knowledge of nature. Galileo made a significant contribution to this development. With his telescopic observations he was, in fact, undermining the prevailing Aristotelian natural philosophy of his day and was defending the birth of modern science against a mistaken view of Scripture. The Church of his time was not prepared to accept his contribution to this theological development. What does this history have to contribute to the challenges we face today in the interactions between science and religious belief?  相似文献   
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To better understand and, therefore, treat Vietnam combat veterans with a diagnosis of posttraumatic stress disorder (PTSD), the Rorschach was administered to 50 patients so diagnosed. The most important findings were that, on average: (a) These patients have a low level of stress tolerance and are, therefore, likely to respond impulsively to stressful situations; (b) this tow stress tolerance appears to be a long-term adjustment problem; and (c) their perception of reality is unconventional and often distorted. A primary therapeutic indication from these data is that the use of structure would be important for successful therapy. Other findings and therapeutic recommendations are also discussed.  相似文献   
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This study examined whether children's growth on measures of fluid (Raven Colored Progressive Matrices) and crystallized (reading and math achievement) intelligence was attributable to domain-specific or domain-general functions of working memory (WM). A sample of 290 elementary school children was tested on measures of intelligence across three testing waves. Two methods, a hierarchical factor model predicting latent growth and a double dissociation design comparing children divided into high and low performers, tested whether general and/or specific components accounted for performance on intelligence measures. A general domain model for the total sample provided the best fit for latent growth on all measures. Further, the lack of a significant WM subgroup × domain interaction suggested that a general WM system underlies the individual differences on measures of fluid and crystallized intelligence. Overall, the findings support a domain-general view of WM capacity on intelligence measures in children, but also suggest that domain specific storage systems may come into play on isolated measures.  相似文献   
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Analyses from the National Comorbidity Study Replication provide the first nationally representative estimates of the co-occurrence of impulsive angry behavior and possessing or carrying a gun among adults with and without certain mental disorders and demographic characteristics. The study found that a large number of individuals in the United States self-report patterns of impulsive angry behavior and also possess firearms at home (8.9%) or carry guns outside the home (1.5%). These data document associations of numerous common mental disorders and combinations of angry behavior with gun access. Because only a small proportion of persons with this risky combination have ever been involuntarily hospitalized for a mental health problem, most will not be subject to existing mental health-related legal restrictions on firearms resulting from a history of involuntary commitment. Excluding a large proportion of the general population from gun possession is also not likely to be feasible. Behavioral risk-based approaches to firearms restriction, such as expanding the definition of gun-prohibited persons to include those with violent misdemeanor convictions and multiple DUI convictions, could be a more effective public health policy to prevent gun violence in the population. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
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Firearm violence is a top-tier public health problem in the U.S., killing 33,563 and injuring an additional 81,396 people in 2012 (Centers for Disease Control and Prevention, CDC, 2015 ). Given constitutional protection and the cultural entrenchment of private gun ownership in the U.S., it is likely that guns will remain widely accessible – and largely unrestricted – for the foreseeable future. Therefore, most policies and laws intended to reduce firearm violence focus selectively on preventing “dangerous people” from having access to guns. That is a formidable challenge. How do we think productively about guns and mental illness in this context, and about the role of law in lessening the toll of gun violence? Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
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