Evidence for altered Fragile-X mental retardation protein expression in response to behavioral stimulation

The Fragile-X mental retardation protein, the protein absent in Fragile-X syndrome, is synthesized near synapses upon neurotransmitter activation. Humans and mice lacking this protein exhibit abnormal dendritic spine lengths and numbers. Here we investigated Fragile-X protein levels in animals exposed to behavioral paradigms that induce neuronal morphological change. Fragile-X protein immunoreactivity was examined in visual cortices of rats reared in a complex environment for 10 or 20 days, motor cortices of rats trained on motor-skill tasks for 3 or 7 days, and either visual or motor cortices of inactive controls. Rats exposed to a complex environment for 20 days or trained for 7 days on motor-skill tasks exhibited increased Fragile-X protein immunoreactivity in visual or motor cortices, respectively. These results provide the first evidence for a behaviorally induced alteration of Fragile-X protein expression and are compatible with previous findings suggesting synaptic regulation of its expression. These results also strengthen the association of Fragile-X mental retardation protein expression with the alteration of synaptic structure.     

Using Intergroup Contact Theory to Reduce Stigma Against Transgender Individuals: Impact of a Transgender Speaker Panel Presentation

Sexual minorities experience significant stigma and prejudice. Much research has examined sexual stigma and prejudice impacting gay and lesbian individuals, but limited research has examined other sexual minorities, such as transgender persons or individuals whose gender identity or expression is incongruent with their assigned gender or anatomical sex. Research has found that interpersonal contact with sexual minorities is associated with lower sexual stigma and prejudice. Intergroup contact theory predicts that interaction between groups can reduce stereotyping and improve intergroup relationships. Using a randomized crossover design, this study compared the impact of exposure to a transgender speaker panel vs. a traditional transgender lecture presentation on transphobia. Results indicated greater immediate reductions of transphobia following the transgender speaker panel than traditional lecture.     

The Obedience of the Eternal Son

According to Karl Barth, the obedience of the eternal Son in the economy of salvation is the proper mode whereby he enacts the undivided work of the Trinity ‘for us and our salvation’. This thesis now enjoys rather wide acceptance among contemporary theologians. In many instances, adopting this viewpoint has resulted in significant revisions of traditional trinitarian metaphysics. The purpose of the present article is to demonstrate that adopting Barth's thesis does not require such revision and that this thesis can and should be appropriated within the orbit of traditional trinitarian theology. We will endeavor to establish our claim by considering the relationship between the Son's eternal generation and his economic obedience, and by addressing three major objections that might be raised against our claim.     

Perceived quality of maternal care in childhood and structure and function of mothers' brain

Animal studies indicate that early maternal care has long‐term effects on brain areas related to social attachment and parenting, whereas neglectful mothering is linked with heightened stress reactivity in the hippocampus across the lifespan. The present study explores the possibility, using magnetic resonance imaging, that perceived quality of maternal care in childhood is associated with brain structure and functional responses to salient infant stimuli among human mothers in the first postpartum month. Mothers who reported higher maternal care in childhood showed larger grey matter volumes in the superior and middle frontal gyri, orbital gyrus, superior temporal gyrus and fusiform gyrus. In response to infant cries, these mothers exhibited higher activations in the middle frontal gyrus, superior temporal gyrus and fusiform gyrus, whereas mothers reporting lower maternal care showed increased hippocampal activations. These findings suggest that maternal care in childhood may be associated with anatomy and functions in brain regions implicated in appropriate responsivity to infant stimuli in human mothers.     

Intensity and direction as dimensions of competitive state anxiety and relationships with competitiveness.

This study examined differences in intensity and direction of symptoms of competitive state anxiety in high and low competitive subjects from the sports of rugby union, basketball, soccer, and field hockey. The 69 men were dichotomized via a median-split into high and low competitive groups based on their scores on the Sport Orientation Questionnaire. All subjects completed a modified version of the Competitive State Anxiety Inventory-2 30 minutes prior to competition. This inventory included the original intensity scale plus a direction scale on which subjects rated the extent the experienced intensity of each symptom was either facilitative or debilitative to subsequent performance. There were no significant group differences on intensity of cognitive anxiety or of somatic anxiety or on direction of somatic anxiety; however, the highly competitive group of 34 subjects reported their anxiety as more facilitative and less debilitative than the low competitive group (n = 35). This supports the proposal that sports performers' directional perceptions of their anxiety symptoms may provide further understanding of the competitive state-anxiety response.     

A longitudinal study of bilingual and cognitive development(1)

This paper presents the findings of a longitudinal study of IQ data collected over a 5-year period (Grades K-4) on pupils enrolled in a French immersion program (anglophone pupils receiving all instruction in French except English language arts) and pupils in the regular English program. Although year-by-year results may fail to show IQ differences between the two groups, repeated measures analysis indicates that the immersion group has a higher IQ measure over the 5-year period. However, considering Grades 1–3 only, which involved the administration of the same test, the two groups do not score differentially with respect to either overall IQ measure or specific subtest scores (classification/categorization, analogies, following of verbal directions) when scores are adjusted for initial IQ (and age) differences, thus failing initially to support studies which show positive relationships between bilingualism and cognitive functioning. However, supportive of those studies is a further analysis on the data of immersion pupils classified as “high” French achievers vs. “low” French achievers. The high French achievers obtain significantly higher IQ measures and subtest scores (analogies and following of verbal directions) than the low French achievers, even when scores are adjusted for initial IQ and age differences. These findings are interpreted in the context of Cummins' (1976) “threshold” hypothesis relating to level of competence in the second language.     

Self-concept and delinquency proneness

Contrary to the theory of the homeostatic model of self-concept, i.e., the expectancy that engaging in anti-social or pro-social behavior results typically in shifts in the self-concept (Graf, 1968; Deitz, 1970 shifts did not occur. Subjects, 12- 14-year-old boys enrolled in junior high school, delinquent prone (DP) and non-delinquent prone bright (NDPB), reacted to manipulation by engaging in reparative behavior as indicated via an aggression module in a fashion generally expected but the expected shift from chronic self-images did not occur. Both DP and NDPB viewed themselves similarly on self concept. The authors postulated that if shifts would occur for the delinquent prone it would be after they left school with its accompanying identification with a sub-culture outside the school setting.     

What's in a baby-cry? Locationist and constructionist frameworks in parental brain responses

Parental brain responses to baby stimuli constitute a unique model to study brain-basis frameworks of emotion. Results for baby-cry and picture stimuli may fit with both locationist and psychological constructionist hypotheses. Furthermore, the utility of either model may depend on postpartum timing and relationship. Endocrine effects may also be critical for accurate models to assess mental health risk and treatment.     

Character Strengths Interventions: Building on What We Know for Improved Outcomes

For this review strengths intervention studies were located using online searches and collegial networks and included if they explicitly sought to teach or use a strengths classification to enhance well-being, and used pre- and post-intervention measures and a comparison group. Eight studies met the criteria and have been summarised by this review. To date, the effect sizes achieved by character strengths interventions have been small to moderate. An understanding of how these interventions work may facilitate development of more effective interventions, while expanding the field of character strengths interventions to include a broader range of activities and approaches may also offer benefits. Research examining individual factors, such as strengths use, psychological need satisfaction, goal-setting and goal-striving provides promising leads to explain how strengths interventions work. However, the effect on intervention efficacy of relational or contextual factors, such as intervention environment or facilitator attitude to strengths, has not yet been explored. Implications for interventions in school settings are considered.     

Perceived Social Support and Type of Cardiac Procedures as Modifiers of Hospital Anxiety and Depression

This study examined the effect of cardiac procedure and perceived social support on anxiety and depression among cardiac patients. The sample included 100 cardiac patients consisting of equal number of patients referred for coronary angiogram and coronary artery bypass surgery. They completed measures of perceived social support, hospital anxiety and depression. The results revealed a significant effect of cardiac procedure on perceived social support, anxiety, and depression. Perceived social support yielded significant negative impact on anxiety and depression.