Determination of dipeptidyl aminopeptidase activities in the cerebrospinal fluid

The investigation of enzyme activity in cerebrospinal fluid has been without relevant results for laboratories analysing spinal fluid. For neurochemical purposes, it is interesting that the Substance P is convered by Depeptidyl-aminopeptidase IV (DP IV), liberating dipeptides. The hydrolysis of nitroanilids of the form Xaa-Pro-NHNp in cerebrospinal fluid was analysed using them as peptidases substrates. Finally a method for measuring the activity was proposed.     

Catamnestic surveys on somato-psychosocial development in childhood and adolescence of patients with unipolar depressive and bipolar manic-depressive psychoses

The somatic and psychosocial development of 80 subjects with manifest affective-phasic psychoses is studied retrospectively and compared with that of an identically sized control group consisting of neuropsychiatrically healthy subjects. Statistically significant differences were found particularly in the answers to questions dealing with social situation and social adaptability. Achievement at school and vocational qualifications were lower among the parents of the patients than among those of the healthy subjects. Characteristic features of the patients' childhood and adolescence were transient depression, often for no apparent cause, and maladaption, and vocational wishes were fulfilled less often than among the controls. The patients experienced greater difficulty in settling in to a new group due to their contact difficulties.     

Competition and Justice in Adam Smith

This article analyzes the relationship between competition and justice in Adam Smith in order to determine to what extent competition can promote and undermine justice. I examine how competition features in two basic motivations for human action, “the propensity to truck barter and exchange,” and “the desire of bettering our condition.” Both can be traced back to the desire for recognition, but they operate in very different ways. The former manifests itself in social cooperation, chiefly commercial exchange and the division of labor, and while it can take a competitive form, competitive success produces benefits for everyone. In contrast, the latter may manifest itself in win-lose social competition. Commercial society harnesses both motivations, and both have negative as well as positive effects. However, while Smith explicitly addresses the negative effects of excessive specialization in the division of labor, it is less clear how he thinks the negative effects of social competition can be addressed. I argue that competition can undermine justice when (i) it pits people against each other and (ii) leads to psychological corruption. I conclude with some reflections on what a focus on competition adds to our understanding of Smith's work.     

Exploring the Context-Sensitivity of Collective Action Motivations and the Mobilizing Role of Social Media: A Comparative Interview Study With Activists in Germany and Turkey

Western scholarship has underlined the relevance of social identity, perceived efficacy, emotions, and cost–benefit assessments as central catalysts of collective action. Little has been done to understand the context-sensitivity of these catalysts by means of cross-culturally comparative designs. The current study explores their context-sensitivity. It aims to find out whether existing opportunity structures in a democratic, nonrepressive country like Germany produce catalysts of collective action different from those produced in an autocratic, repressive country like Turkey. It also aims to understand the role of social media in mobilizing people in these two contexts. Semistandardized interviews with activists were carried out in both countries (n = 18 in Germany and n = 15 in Turkey) and analyzed by means of a cross-culturally comparative inductive coding procedure including initial and focused coding. Results show that collective action is related to different configurations of collective-action catalysts in the two countries. Solidarity concerns at the face of existential risks are more pronounced in Turkey, whereas political-change concerns are more important in Germany. The role of social media accordingly differs, adhering to the different activist goals. Theoretical implications for the role of context in studying collective action are discussed.     

A systematic review of relationship sacrifices from 2002 to 2021: Moving toward inclusivity

We conducted a systematic review of research on relational sacrifices in romantic relationships from 2002 to 2021 [N = 115 studies] to answer three questions: Q1: Whose voices and vantage points are represented in the research?; Q2: What types of questions are valued?; Q3: What are the reflections and connections about relational sacrifices that were learned during the review? To address Q1, we coded sample demographics of study participants on geographical location, race/ethnicity, education/income/SES, gender (i.e., gender differences explored and beyond gender binaries), sexual orientation, age, and disability, using a coding system of 1 (exclusion/absence) to 5 (focus on context-relevant experiences for underrepresented samples). Results for Q1 showed that the most frequent codes were 1 (exclusion/absence) for information about the samples' disability status, education/income/SES, and both codes for gender (i.e., gender differences explored and beyond gender binaries); when demographic information was reported, the most frequent codes were 2 (compensatory addition) for age, sexual orientation, geographical location, and race/ethnicity. To address Q2, we coded for aspects of the study designs and conceptual dimensions of sacrifice. Results for Q2 showed that a majority of the studies in our review used quantitative and close-ended measures emphasizing behavioral frequency of sacrifice. For Q3, we include our own reflections and connections about relational sacrifices, questioning research methods, and challenging assumptions drawn from existing research to move toward a more inclusive science.     

Visual context processing and its development in gamers and non-gamers

Visual context processing was investigated in both action video game players and nonplayers using the Ebbinghaus illusion task (N = 312, 39.4% female) in a cross-sectional study design. When presented in context, players showed markedly poorer target size discrimination accuracy compared with nonplayers in the 6-, 7-, 8-, and 9-years old age groups, but this difference was reduced in 10-years old group and diminished in adults. When presented in isolation (no-context), the two groups displayed similar performance in all age groups. Furthermore, nonplayers (linear) and players (bell curve) showed profoundly different age-related differences in context processing. These findings provide evidence that players might have enhanced perceptual bias to process visual context in the transition from early childhood to early adolescence, and the differences between the two groups start at early ages and continue with distinct developmental profiles.     

Context-dependent alarm responses in wild vervet monkeys

Animal Cognition - The alarm calls of nonhuman primates are occasionally cited as functionally equivalent to lexical word meaning in human language. Recently, however, it has become increasingly...     

Heterogeneous heterogeneity by default: Testing categorical moderators in mixed-effects meta-analysis

Categorical moderators are often included in mixed-effects meta-analysis to explain heterogeneity in effect sizes. An assumption in tests of categorical moderator effects is that of a constant between-study variance across all levels of the moderator. Although it rarely receives serious thought, there can be statistical ramifications to upholding this assumption. We propose that researchers should instead default to assuming unequal between-study variances when analysing categorical moderators. To achieve this, we suggest using a mixed-effects location-scale model (MELSM) to allow group-specific estimates for the between-study variance. In two extensive simulation studies, we show that in terms of Type I error and statistical power, little is lost by using the MELSM for moderator tests, but there can be serious costs when an equal variance mixed-effects model (MEM) is used. Most notably, in scenarios with balanced sample sizes or equal between-study variance, the Type I error and power rates are nearly identical between the MEM and the MELSM. On the other hand, with imbalanced sample sizes and unequal variances, the Type I error rate under the MEM can be grossly inflated or overly conservative, whereas the MELSM does comparatively well in controlling the Type I error across the majority of cases. A notable exception where the MELSM did not clearly outperform the MEM was in the case of few studies (e.g., 5). With respect to power, the MELSM had similar or higher power than the MEM in conditions where the latter produced non-inflated Type 1 error rates. Together, our results support the idea that assuming unequal between-study variances is preferred as a default strategy when testing categorical moderators.     

The effect of microlevel and macrolevel signaling on learning with 360° videos

The application of 360° videos raised the attention of educators and researchers, as it appears to be an approachable option to mediate complete environments in educational settings. However, challenges emerge from the perspective of educational psychology. Learning irrelevant cognitive strains might be imposed because it is necessary to navigate through spherical material. However, these potential downsides could be compensated for using signaling techniques. In a two (macrolevel vs. no macrolevel signaling) × two (microlevel vs. no microlevel signaling) factorial between-subjects design plus control group, 215 fifth-and sixth-grade students will watch a 360° video about visual and behavioral characteristics of animals. Learning outcomes, cognitive load, disorientation, and presence will be investigated. It is expected that macrolevel signaling will enhance learning and presence and reduce cognitive load and disorientation. Microlevel signaling will have comparable advantages, but these effects will be more pronounced when macrolevel signaling is implemented.     

Behavioral consequences of intergroup sensitivity

Communication of criticism between groups is important to productive societal discourse, but may serve to inflame conflict. The defensive rejection of intergroup, relative to intragroup, criticism (intergroup sensitivity effect [ISE]) may contribute to such divides. The ISE has been observed in self-report measures, but such measures are weak and biased predictors of actual (divisive) behavior. We review recent research demonstrating that the ISE does have costly behavioral consequences. We next consider the debate concerning whether the ISE reflects defense of a valued social identity or enforcement of a conversational norm. We therefore review recent evidence for an ISE among individuals lacking identification with the target of the criticism. Third, we examine how the ISE may affect a variety of behaviors relevant to societal divisions, including political reconciliation, environmental sustainability, and vaccination. Lastly, we outline future research that can clarify the underlying mechanisms of the ISE and promote conciliatory intergroup behavior.