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41.
Sullivan RM 《Stress (Amsterdam, Netherlands)》2004,7(2):131-143
The prefrontal cortex (PFC) is known to play an important role not only in the regulation of emotion, but in the integration of affective states with appropriate modulation of autonomic and neuroendocrine stress regulatory systems. The present review highlights findings in the rat which helps to elucidate the complex nature of prefrontal involvement in emotion and stress regulation. The medial PFC is particularly important in this regard and while dorsomedial regions appear to play a suppressive role in such regulation, the ventromedial (particularly infralimbic) region appears to activate behavioral, neuroendocrine and sympathetic autonomic systems in response to stressful situations. This may be especially true of spontaneous stress-related behavior or physiological responses to relatively acute stressors. The role of the medial PFC is somewhat more complex in conditions involving learned adjustments to stressful situations, such as the extinction of conditioned fear responses, but it is clear that the medial PFC is important in incorporating stressful experience for future adaptive behavior. It is also suggested that mesocortical dopamine plays an important adaptive role in this region by preventing excessive behavioral and physiological stress reactivity. The rat brain shows substantial hemispheric specialization in many respects, and while the right PFC is normally dominant in the activation of stress-related systems, the left may play a role in countering this activation through processes of interhemispheric inhibition. This proposed basic template for the lateralization of stress regulatory systems is suggested to be associated with efficient stress and emotional self-regulation, and also to be shaped by both early postnatal experience and gender differences. 相似文献
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Sullivan G 《Journal of the history of the behavioral sciences》2004,40(2):183-206
Beginning in 1933, while working in New Guinea, Margaret Mead developed her so-called squares hypothesis. Mead never published its terms, though she made a brief comment on it in her autobiography, Blackberry Winter (1972), and the arguments found in Sex and Temperament in Three Primitive Societies (1935) and the research leading to Balinese Character (Bateson & Mead, 1942) bore its imprint. Beginning with William McDougall's distinction between temperament (innate predispositions) and character (learned organization of habit), Mead articulated a morphological approach to the interplay between biology and culture that yielded four primary and four intermediary personality types. Under specified but not inevitable circumstances, the conscious choices of a given people could render one or another of these types characteristic or predominantly stable within their population, giving each of the other types a definite relation to the dominant type and thereby the cultural ethos of its society. Persons of each type followed a developmental path specific to their type different both from that of other types and in its manifestations given the various relations of the individual's type to the dominant type. Mead's hypothesis was, therefore, a vision of the unity and diversity of a single human species as well as an approach to the differing psychological positioning of individuals in cultures. In examining Mead's hypothesis, this essay also takes up Mead's debts to several leading psychologists (McDougall, C. G. Jung, and Erik Erikson), and (provisionally) how her vision differed from that of Ruth Benedict. 相似文献
44.
Giovanello KS Verfaellie M Keane MM 《Cognitive, affective & behavioral neuroscience》2003,3(3):186-194
In two experiments, we tested the hypothesis that medial temporal lobe (MTL) amnesic patients and, likewise, diencephalic
(DNC) amnesic patients evidence a disproportionate deficit in memory for associations in comparison with memory for single
items. In Experiment 1, we equated item recognition in amnesic and control participants and found that, under these conditions,
associative recognition remained impaired both for MTL patients and for DNC patients. To rule out an alternative interpretation
of the results of Experiment 1, in Experiment 2 we compared the performance of amnesic and control participants on a one-item
recognition task and a two-item recognition task that required no memory for the association between members of word pairs.
In the MTL group, when single-item recognition was equated to that of the controls, two-item nonassociative pair memory was
equivalent as well. In the DNC group, nonassociative pair memory was impaired, but this impairment did not fully account for
the impairment in associative memory. These findings indicate that memory for novel associations between items is disproportionately
impaired in comparison with memory for single items in amnesia. 相似文献
45.
Psychological distress,help‐seeking,and perceived barriers to psychological treatment among Australian parents 下载免费PDF全文
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A profound anterograde memory deficit for information, regardless of the nature of the material, is the hallmark of Korsakoff syndrome, an amnesic condition resulting from severe thiamine (vitamin B1) deficiency. Since the late nineteenth century when the Russian physician, S. S. Korsakoff, initially described this syndrome associated with "polyneuropathy," the observed global amnesia has been a primary focus of neuroscience and neuropsychology. In this review we highlight the historical studies that examined anterograde episodic memory processes in KS, present a timeline and evidence supporting the myriad theories proffered to account for this memory dysfunction, and summarize what is known about the neuroanatomical correlates and neural systems presumed affected in KS. Rigorous study of KS amnesia and associated memory disorders of other etiologies provide evidence for distinct mnemonic component processes and neural networks imperative for normal declarative and nondeclarative memory abilities and for mnemonic processes spared in KS, from whence emerged the appreciation that memory is not a unitary function. Debate continues regarding the qualitative and quantitative differences between KS and other amnesias and what brain regions and neural pathways are necessary and sufficient to produce KS amnesia. 相似文献
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Vocal tract resonances, called formants, are the most important parameters in human speech production and perception. They
encode linguistic meaning and have been shown to be perceived by a wide range of species. Songbirds are also sensitive to
different formant patterns in human speech. They can categorize words differing only in their vowels based on the formant
patterns independent of speaker identity in a way comparable to humans. These results indicate that speech perception mechanisms
are more similar between songbirds and humans than realized before. One of the major questions regarding formant perception
concerns the weighting of different formants in the speech signal (“acoustic cue weighting”) and whether this process is unique
to humans. Using an operant Go/NoGo design, we trained zebra finches to discriminate syllables, whose vowels differed in their
first three formants. When subsequently tested with novel vowels, similar in either their first formant or their second and
third formants to the familiar vowels, similarity in the higher formants was weighted much more strongly than similarity in
the lower formant. Thus, zebra finches indeed exhibit a cue weighting bias. Interestingly, we also found that Dutch speakers
when tested with the same paradigm exhibit the same cue weighting bias. This, together with earlier findings, supports the
hypothesis that human speech evolution might have exploited general properties of the vertebrate auditory system. 相似文献
50.