Summation priming in aphasia: evidence for alterations in semantic integration and activation

The present study used a lexical decision paradigm to study the summation of priming effects in normal and aphasic participants. The amount of priming produced by pairs of definitionally converging associative words was compared to the amount of priming produced by pairs of single associative words and non-words in two experiments in which the ISI between primes and targets varied from 200 ms (Experiment 1) to 600 ms (Experiment 2). Control subjects showed a pattern of additive summation priming at the short ISI and overadditive summation priming at the longer ISI. Broca's aphasics showed overadditive priming at the short ISI and no significant priming at the longer ISI; Wernicke's aphasics showed no significant priming at the short ISI and additive priming at the longer ISI. These results suggest that aphasics differ from normals in their ability to integrate the activation derived from multiple linguistic associations and may provide an account of some of the clinical phenomenology of these patients.     

Psychological briefs of interest to ministers

Pastoral Psychology -     

Short-term retention of tactile stimulation

In three experiments subjects were required to reproduce after varying delays the locus of a tactile stimulation delivered to the upper-side of the arm. During the retention periods subjects either performed a subsidiary, arithmetic task or rested. Recall, as measured by accuracy in reproducing the locus of stimulation, decreased as a function of retention interval, asymptoting after approximately 5 s. Performance was poorer in the subsidiary task condition than in the rest condition; however, the effect of the subsidiary task appeared to be more on subject recall strategies than on rehearsal capacity. No evidence of proactive interference effects was found, and a decay interpretation of forgetting of discrete tactile stimuli in the short-term memory distractor paradigm was favoured.     

Not the End of the Odyssey: Parental Perceptions of Whole Exome Sequencing (WES) in Pediatric Undiagnosed Disorders

Due to the lack of empirical information on parental perceptions of primary results of whole exome sequencing (WES), we conducted a retrospective semi-structured interview with 19 parents of children who had undergone WES. Perceptions explored during the interview included factors that would contribute to parental empowerment such as: parental expectations, understanding of the WES and results, utilization of the WES information, and communication of findings to health/educational professionals and family members. Results of the WES had previously been communicated to families within a novel framework of clinical diagnostic categories: 5/19 had Definite diagnoses, 6/19 had Likely diagnoses, 3/19 had Possible diagnosis and 5/19 had No diagnosis. All parents interviewed expressed a sense of duty to pursue the WES in search of a diagnosis; however, their expectations were tempered by previous experiences with negative genetic testing results. Approximately half the parents worried that a primary diagnosis that would be lethal might be identified; however, the hope of a diagnosis outweighed this concern. Parents were accurately able to summarize their child’s WES findings, understood the implications for recurrence risks, and were able to communicate these findings to family and medical/educational providers. The majority of those with a Definite/Likely diagnosis felt that their child’s medical care was more focused, or there was a reduction in worry, despite the lack of a specific treatment. Irrespective of diagnostic outcome, parents recommended that follow-up visits be built into the process. Several parents expressed a desire to have all variants of unknown significance (VUS) reported to them so that they could investigate these themselves. Finally, for some families whose children had a Definite/Likely diagnosis, there was remaining frustration and a sense of isolation, due to the limited information that was available about the diagnosed rare disorders and the inability to connect to other families, suggesting that for families with rare genetic disorders, the diagnostic odyssey does not necessarily end with a diagnosis. Qualitative interviewing served a meaningful role in eliciting new information about parental motivations, expectations, and knowledge of WES. Our findings highlight a need for continued communication with families as we navigate the new landscape of genomic sequencing.     

How positive processes function in negative relationships: Dispositional gratitude moderates the association between affective need and frequency of dating violence victimization

Evidence indicates that dispositional gratitude may improve romantic relationships by reinforcing positive emotions between partners and by increasing awareness of affective needs, such as receiving emotional support, nurturance, and reassurance. However, little research has investigated the influence of gratitude on relationships characterized by violence. In the present study, participants (N = 421) completed a cross-sectional survey of experiences with dating violence, dispositional gratitude, and affective need. Data were analyzed using structural equation modeling. Among individuals with lower rates of dispositional gratitude, higher levels of affective need were associated with lower frequency of dating violence victimization. However, among individuals with higher rates of dispositional gratitude, there was no evidence to suggest an association between affective need and frequency of victimization. These preliminary findings compel further investigation of how positive processes impact the perceived qualities of negative romantic relationships.