Propofol induction reduces the capacity for neural information integration: Implications for the mechanism of consciousness and general anesthesia

The cognitive unbinding paradigm suggests that the synthesis of neural information is attenuated by general anesthesia. Here, we analyzed the functional organization of brain activities in the conscious and anesthetized states, based on functional segregation and integration. Electroencephalography (EEG) recordings were obtained from 14 subjects undergoing induction of general anesthesia with propofol. We quantified changes in mean information integration capacity in each band of the EEG. After induction with propofol, mean information integration capacity was reduced most prominently in the γ band of the EEG (p = .0001). Furthermore, we demonstrate that loss of consciousness is reflected by the breakdown of the spatiotemporal organization of γ waves. We conclude that induction of general anesthesia with propofol reduces the capacity for information integration in the brain. These data directly support the information integration theory of consciousness and the cognitive unbinding paradigm of general anesthesia.     

Skill transfer through goal-driven representation mapping

In this paper, we present an approach to transfer that involves analogical mapping of symbols across different domains. We relate this mechanism to Icarus, a theory of the human cognitive architecture. Our system can transfer skills across domains hypothesizing maps between representations, improving performance in novel domains. Unlike previous approaches to analogical transfer, our method uses an explanatory analysis that compares how well a new domain theory explains previous solutions under different mapping hypotheses. We present experimental evidence that the new mechanism improves transfer over Icarus’ basic learning processes. Moreover, we argue that the same features which distinguish Icarus from other architectures support representation mapping in a natural way and operate synergistically with it. These features enable our analogy system to translate a map among concepts into a map between skills, and to support transfer even if two domains are only partially analogous. We also discuss our system’s relation to other work on analogy and outline directions for future research.     

Social and Situational Factors Associated With Contraceptive Switching: Implications for Practitioners1

This study was an investigation of contraceptive switching in the context of a 5-wave panel design of diaphragm and pill users from the New York City metropolitan area. The respondents were 525 women between the ages of 14 and 46, who came to one of 10 family planning clinics to obtain birth control, Results indicated a hazard function for switching in which the hazard rate increased in the initial weeks and then gradually declined over time. Clinic experiences on the part of the women were found to alter survivorship trends. Implications of the data for service providers were developed.     

Chronic self-destructiveness: Conceptualization,measurement, and initial validation of the construct

Individual differences in various behaviors suggest that those who are primarily motivated by current emotional factors are more likely than those motivated by more distant cognitive considerations to engage in acts that are ultimately self-destructive. To assess and explore these behavioral differences, 12 samples of undergraduate subjects, totaling 864 (527 females, 337 males), a group of 15 businesswomen, and 111 male VA patients were used to develop a measure of this construct in a series of reliability and construct validity studies. By means of internal-consistency item analyses, two cross-validated 52-item measures of chronic self-destructiveness were constructed for males and females. Reliability was established with respect to internal consistency (alpha coefficients range from .73 to .97) and temporal consistency over a 1-month period (test-retest correlations range from .90 to .98). There is a slight drop in chronic self-destructiveness scores across age groups. Test scores were found to be positively related to external locus of control, negatively related to Type A coronary-prone behavior, and unrelated to either social desirability response set or need for achievement. Individuals high in chronic self-destructiveness, compared to those with low scores, are more likely to be in treatment for drug or alcohol abuse, to report having cheated in courses, to have had traffic violations, to report having gone through a rebellious stage in adolescence, and to postpone obtaining a medical test for cancer. Chronic self-destructiveness appears to be a personality dimension that affects behavior across a wide range of ages and situations.We wish to thank John Wapner for his assistance in obtaining data in the clinical sample.     

Judgments of Highly Creative Advertising: Presence of Functional Matching and the FCB Planning Model in Clio-Winning Advertisements

Highly creative advertisements are the end-products of creativity in advertising, and their creation is generally thought to be driven by strategic planning. Thus, 534 Clio-awarded advertisements from the years 2011–2014 were content-analyzed to determine whether implications of two popular planning frameworks, functional matching and the Foote, Cone, and Belding Planning Model, were present in the industry’s best creative work. Since 1960, the Clio Award Program has annually recognized the world’s most creative advertisements. Clio-awarded advertisements are selected by panels of advertising experts specifically constituted to offset gender and country of origin bias. The study found that implications of the two planning frameworks were not present in the industry’s most creative work: types of value-expressive appeals were more frequent than types of utilitarian appeals in Clio-awarded advertisements, regardless of the nature of the advertised products or the category of media used to deliver product messaging. These findings support previous research, which found that highly creative advertising rarely is based on strategic considerations. However, they were inconsistent with other research regarding the presence of the two planning frameworks in general TV advertising.     

Evaluating the Effectiveness of a Group CBT for Parents of ADHD Children

Improvements in parenting skills do not necessarily lead to improvements in child and parent outcomes for children with attention deficit and hyperactivity disorder (ADHD). Cognitive factors such as parental cognitions and parenting self-efficacy may influence such outcomes. Clinical research on the effects of cognitive-behaviour therapy (CBT) on parental cognitions, parenting self-efficacy and mental health in Chinese parents of children with ADHD is lacking. This quasi-experimental study intended to assess the effects of a culturally attuned group CBT treatment on the mental health and quality of life of Chinese parents aged 26–58 years, with children with ADHD in Hong Kong. Participants in the experimental group received group CBT and standard treatment and their counterparts in the control group received standard treatment. Primary outcome variables of mental health and quality of life and process variables including parenting stress, parenting efficacy and dysfunctional attitudes were measured at baseline, post-treatment and 3-month follow-up. Data were analysed using 2?×?3 ANCOVAs, Cohen’s d statistics and multiple mediation analyses. Group by time interactions were found for most outcome variables. Effect size statistics indicated that group CBT had small to moderate effects on most outcome variables at post-treatment and follow-up assessments. The effect of CBT on mental health was mediated by the reduction in parenting stress and the effect of CBT on quality of life was mediated by the reductions in parenting stress and dysfunctional attitudes. Given its potential benefit, it is worth considering incorporating this group CBT programme into interventions for Chinese parents with ADHD children.     

Developmental considerations for assessment of trauma symptoms in preschoolers: a review of measures and diagnoses

Child maltreatment can lead to a unique set of trauma stress among young children that can be challenging to measure. The purpose of this review was to review measures of maltreatment-related trauma outcomes (trauma-related symptoms and post-traumatic stress disorders) in very young children (ages 0–6) and to examine research trends in how and if child development is accounted for in this area of measurement. A systematic search strategy was used to identify articles in two databases, CINAHL and PsychInfo. Articles were eligible for inclusion in the review if they measured trauma symptoms in children ages 0–6, were quantitative research reports of studies conducted in North America, and were published in English. The search resulted in 74 articles meeting prespecified inclusion criteria. Results suggested that recognition of the ways maltreatment trauma affects child development and the importance of developmental sensitivity in assessing trauma symptoms has grown in recent years. However, many research studies did not use developmental frameworks and applied adult-oriented trauma symptom frameworks in measurement and treatment. Behavioral symptoms were the primary outcome of interest for this age group. There was also incongruity and lack of consensus about diagnostic tools for post-traumatic stress disorders in young children. Further research is needed to resolve theoretical and empirical controversies related to measurement and diagnosis of trauma symptomatology in young children.     

Gami-Chunghyuldan ameliorates memory impairment and neurodegeneration induced by intrahippocampal Aβ 1-42 oligomer injection

Soluble oligomeric forms of amyloid beta (AβO) are regarded as a main cause of synaptic and cognitive dysfunction in Alzheimer’s disease (AD) and have been a primary target in the development of drug treatments for AD. The present study utilized a mouse model of AD induced by intrahippocampal injection of AβO (10 μM) to investigate the effects of Gami-Chunghyuldan (GCD), a standardized multi-herbal medicinal formula, on the presentation of memory deficits and neurohistological pathogenesis. GCD (10 and 50 mg/kg/day, 5 days, p.o.) improved AβO-induced memory impairment as well as reduced neuronal cell death, astrogliosis, and microgliosis in the hippocampus. In addition, GCD prevented AβO-triggered synaptic disruption and cholinergic fiber loss. These results suggest that GCD may be useful in the prevention and treatment of AD.     

Sex role group differences in specific, academic, and general self-efficacy

The primary purpose of this study was to examine sex role group differences (androgynous, masculine, feminine, and undifferentiated) in three different levels of self-efficacy (general, academic, and course specific). A sample of 215 undergraduate participants completed the three measures of self-efficacy and the sex role measure. Results showed that there was a multivariate significance among the sex role groups in the three levels of self-efficacy and that both masculine and androgynous groups had significantly higher general and academic efficacy means than the undifferentiated or feminine groups. The major findings in this study are largely consistent with findings of previous researchers, supporting the theory that masculinity may be a key construct in the differentiation of individuals in self-efficacy, which has been shown to be an important predictor of achievement.