Identity matching to sample and exclusion performance in elderly with and without neurocognitive disorders

Neurocognitive disorders (NCDs) affect complex processes of stimulus control, such as relational performance. The aims of this study were (a) to compare the performance of older adults with NCD with that of control older adults in generalized identity matching (GI) tests and in responding by exclusion probes and (b) to verify the effect of identity matching training on subsequent GI and exclusion tests, in older adults with NCD. Participants were 24 older adults (aged 60 to 92 years), eight without NCD (control group I [CG I]), and 16 with NCD: CG II, with accurate performance in the GI tests and the experimental group (EG), with low performance in these tests. After exclusion and GI tests with all participants, the EG underwent identity matching training with 3 pairs of visual stimuli, and exclusion and identity matching posttests. All participants of the CG I and CG II presented accurate performance in the tests. Seven of the 8 older adults of the EG achieved the learning criterion in the training and showed some improvement in the GI posttest; however, positive effects of the training were not observed in the exclusion posttests. Teaching procedures for identity matching in older adult patients with NCD can produce positive results; however, it is necessary to understand the relationship between cognitive decline and other relational performances.     

Activation of MAPK is necessary for long-term memory consolidation following food-reward conditioning

Although an important role for the mitogen-activated protein kinase (MAPK) has been established for memory consolidation in a variety of learning paradigms, it is not known if this pathway is also involved in appetitive classical conditioning. We address this question by using a single-trial food-reward conditioning paradigm in the freshwater snail Lymnaea stagnalis. This learning paradigm induces protein synthesis-dependent long-term memory formation. Inhibition of MAPK phosphorylation blocked long-term memory consolidation without affecting the sensory and motor abilities of the snails. Thirty minutes after conditioning, levels of MAPK phosphorylation were increased in extracts from the buccal and cerebral ganglia. These ganglia are involved in the generation, modulation, and plasticity of the feeding behavior. We also detected an increase in levels of MAPK phosphorylation in the peripheral tissue around the mouth of the snails where chemoreceptors are located. Although an increase in MAPK phosphorylation was shown to be essential for food-reward conditioning, it was also detected in snails that were exposed to the conditioned stimulus (CS) or the unconditioned stimulus (US) alone, suggesting that phosphorylation of MAPK is necessary but not sufficient for learning to occur.     

The Impact of Religiosity and Individual Prayer Activities on Advanced Cancer Patients’ Health: Is There Any Difference in Function of Whether or Not Receiving Palliative Anti-neoplastic Therapy?

Consecutive patients (n = 221) presenting for initial consultation at a palliative care outpatient clinic were prospectively interviewed and then followed until death. Individual prayer activity (IPA) and global religion scores were associated with quality of life, symptoms, inflammatory markers, and survival. Analyses were adjusted for whether patients were still receiving anti-neoplastic therapies (ANTs) or not. Higher religion scores were associated with lower levels of inflammation in advanced cancer patients still undergoing ANTs. Additionally, higher IPA was an independent good prognostic factor in patients on active ANTs. Further studies are necessary to confirm these findings and to investigate possible biological mechanisms involved.     

Apathy or alienation? Political passivity among youths across eight European Union countries

Abstract

Political participation is one of the most studied aspects of the contemporary development of western democracies. A recent trend focuses the lack of political participation among younger generations. At the same time, the last decades have also witnessed a growth in the share of young European Union (EU) citizens who express alienation, and distrust toward social and political institutions at the national as well as the European level. By studying young people across different countries of the EU, the current study aims to examine if youths’ political passivity is better explained by political apathy or alienation. Our analyses are based on a comparative survey data collected by the Catch-EyoU project comprising approximately 4 454 late adolescents assembled from eight member countries of the EU. Results from logistic regressions predicting non-voting from apathy and alienation support the idea that political passivity is best understood as the result of political apathy. Moreover, it seems that the underlying separator of apathetic and alienated youths is cognitive awareness of political life. These results are discussed in relation to potentially built-in paradoxes of apathy present in efficient and well-functional welfare-state democracies.     

Early Maternal Spatial Support for Toddlers and Math Skills in Second Grade

ABSTRACT

The aim of this study is to investigate whether maternal spatial support during two types of joint manipulative toy play tasks with 2-year-old children was longitudinally associated with math screening test scores in second grade. The interaction between spatial support and maternal education was explored as well. We also investigated predictions of a teacher rating of math performance at second grade, although these effects were less robust. Data were drawn from BONDS (The Behavior Outlook Norwegian Developmental Study), a longitudinal study of Norwegian children and their families. Participants were a subsample of 932 mothers and their 2-year-olds. Mothers were asked to help their children solve both a puzzle task and a shape-color sorting task. Mothers’ spatial support included spatial language, gestures, and placement of objects. Results showed that higher levels of spatial support during mother-child interaction tasks at 2 years of age was significantly associated with fewer math difficulties in second grade. This was the case for a puzzle task (a task associated with spatial visualization skills), but not for a shape-color sorting task (a task associated with shape and color feature discriminations). Conclusions are drawn with respect to the importance of identifying optimal parental spatial strategies associated with better math outcomes. These findings on parental facilitation of spatial skills during joint early play may be useful for future training interventions directed at parents of children at risk for poor math skills.