继时呈现条件下类别归纳过程的ERPs研究

采用ERP技术对继时呈现条件下类别归纳过程进行了实验研究.使用几何图形为材料,18名被试在单维属性不告知、单维属性告知、双维属性不告知三种条件下完成类别归纳任务.通过对相关ERP成分的分析得出以下结论:(1)在继时呈现归纳材料的情况下,对刺激的加工是在已有背景基础上对后来呈现的刺激进行选择性加工,从而形成类别;(2)成年人与儿童在类别归纳中认知加工方式可能存在不同,当类别归纳的复杂程度增加时,即在需要归纳的属性从一个变为两个的时候,成年人仍然倾向于通过归纳出类别判断规则用于分类任务,而非通过相似性进行判断;(3)继时呈现材料条件下类别归纳任务中出现的P400可能是标志类别归纳过程完成的ERP成分,而且与对刺激属性加工具体过程无关.     

螺旋CT双期增强薄层扫描对小胰腺癌诊断的研究

为了研究螺旋CT胰腺期、肝脏期双期增强薄层扫描在小胰腺癌早期诊断中的作用,对25例小胰腺癌患者行螺旋CT双期增强扫描,结果显示,两组观察结果经统计学处理有显著性差异,螺旋CT动态增强薄层2mm扫描比5mm扫描可明显提高小胰腺癌和微胰腺癌的检出率,对小胰腺癌的早期诊断有重要的临床价值。肝脏期扫描为临床确定肿瘤是否能够手术切除提供科学依据。     

Within-person variability in response speed as an indicator of cognitive impairment in older adults

Within-person variability may be an important indicator of central nervous system compromise. In this study, within-person variability in response speed was examined in community-dwelling older adults, ages 64-92 years, using a new framework that takes into account both the extent (single versus multiple domains affected) and nature (amnestic versus non-amnestic) of the cognitive impairment. Those with multiple domains of impairment were more variable than those who showed an isolated area of impairment, regardless of whether memory was one of the domains affected. Further, for those with difficulties in two or more non-memory domains, increased variability was most evident in more cognitively demanding situations, when individuals had to manipulate information held briefly in mind, switch cognitive set or inhibit an automatic response. Finally, group differentiation was better achieved when within-person variability as opposed to mean speed of performance was considered.     

艺术设计中创造性思维的fMRI研究：一项基于智能CAD的探索

本项工作尝试将人类思维的神经生物学基础研究与人工智能的研究成果相结合, 利用类比生成模型的原理, 开发了一个计算机辅助设计系统“多源类比人脸生成系统”, 并运用此平台开展了fMRI实验, 对人类大脑创造性思维的神经生物学机制进行了探索。实验采用open-ends模式下的“design task”和problem solving模式下的“control task”作为对照, 共采得15名健康成人被试的有效数据。数据结果显示design task与control task相比更为显著地激活了内侧前额叶、额中回、右侧颞上回、前扣带回、双侧海马、楔前叶这些脑区。综合以往研究推测, 内侧前额叶可能更多地与即兴自由创作中对自我信息的表征有关, 颞叶可能与不断产生和输出新颖性的观点有关, 边缘系统则可能主要与创造性活动中的动力驱动作用有关。总的来说, 创造性思维是多个脑区同时参与的高度分布式加工的结果。     

词汇熟悉度对非熟练中英双语者语言理解转换中非目标语言激活的影响

采用改造后的长时重复启动范式,探讨母语为汉语的非熟练中英双语者语言理解转换中非目标语言的激活层面,以及词汇熟悉度的影响。实验1考察学习阶段不同熟悉度的非目标词在测验阶段呈现时能否出现长时重复启动效应,从而检测双语者语言理解转换中非目标语言是否自动激活,实验2探究学习阶段不同熟悉度的非目标词在测验阶段以翻译对等词呈现时能否出现长时重复启动效应,从而检测双语者语言理解转换中非目标语言的语义层面能否激活。结果发现:非熟练中英双语者语言理解转换中非目标语言不管为中文还是英文,都能自动激活,但激活层面会受到词汇熟悉度的影响;当非目标语言为二语时,熟悉度高的二语词能激活到语义层面,熟悉度低的二语词只能激活到词汇层面;当非目标语言为一语时,不管词汇熟悉度高还是低,都能够激活到语义层面。     

Toward a taxonomic model of attention in effortful listening

In recent years, there has been increasing interest in studying listening effort. Research on listening effort intersects with the development of active theories of speech perception and contributes to the broader endeavor of understanding speech perception within the context of neuroscientific theories of perception, attention, and effort. Due to the multidisciplinary nature of the problem, researchers vary widely in their precise conceptualization of the catch-all term listening effort. Very recent consensus work stresses the relationship between listening effort and the allocation of cognitive resources, providing a conceptual link to current cognitive neuropsychological theories associating effort with the allocation of selective attention. By linking listening effort to attentional effort, we enable the application of a taxonomy of external and internal attention to the characterization of effortful listening. More specifically, we use a vectorial model to decompose the demand causing listening effort into its mutually orthogonal external and internal components and map the relationship between demanded and exerted effort by means of a resource-limiting term that can represent the influence of motivation as well as vigilance and arousal. Due to its quantitative nature and easy graphical interpretation, this model can be applied to a broad range of problems dealing with listening effort. As such, we conclude that the model provides a good starting point for further research on effortful listening within a more differentiated neuropsychological framework.     

文化对个体风险感知的影响:文化认知理论的解释

文化认知理论旨在从个体层面研究与文化因素相关的个体风险感知差异。它以"格-群"维度划分文化世界观,"格"维度衡量社会的制度化程度,"群"维度衡量社会群体对个体的影响程度,由此编制文化认知量表以测量个体文化理念差异。目前已验证认同保护认知、偏见同化与群体极化、文化易得性、文化可信性、文化认同确认五种作用机制,并在情感启发式研究的基础上引入文化冲突模因作为中介变量建立理论模型。后续研究可推进文化认知测量工具的跨文化检验与本土化修订,并在具体风险主题研究的基础上探索切实可行的公共风险管理对策。     

青少年未来时间洞察力和学业成绩的关系:时间管理倾向的中介作用

思考未来对个体现在行为具有重要指导意义。本研究以1002名初、高中学生为调查对象,采用问卷调查法探究未来时间洞察力与学业成绩间的关系,以及时间管理倾向在其中的中介作用。结果表明:(1)学业成绩高低分组在未来时间洞察力各维度和时间管理倾向上差异显著。(2)未来积极、未来坚持、未来清晰和未来计划与时间管理倾向和学业成绩呈显著正相关,未来消极和未来迷茫与时间管理倾向和学业成绩呈显著负相关。(3)未来消极对学业成绩具有显著的直接预测作用;未来消极还通过时间效能感间接影响学业成绩;时间管理倾向在未来迷茫、未来清晰、未来坚持、未来计划和学业成绩之间起中介作用。     

Group interventions for patients with cancer and HIV disease: Part I: Effects on psychosocial and functional outcomes at different phases of illness

Group interventions for individuals facing cancer or HIV disease have drawn considerable attention among researchers and clinicians over the past 20 years. There is growing evidence that group services may be helpful, but which interventions are most effective for participants at which phases in the trajectory of disease has been less clear. Moreover, professionals working in different intervention settings (e.g., primary prevention vs. clinical care) and different disease sites (cancer vs. HIV disease) often have little awareness of relevant advances in other fields. Efforts to integrate findings in the literature may accelerate research and advance the standard of clinical care. The current article, the first in a series of four special reports, critically evaluates the efficacy of group interventions led by professional or trained facilitators for individuals confronted by cancer or HIV, across the spectrum of illness from elevated risk through advanced disease. We examine psychosocial and functional outcomes for different interventions directed toward different patient subgroups, trace common themes, highlight limitations, and offer recommendations for further research.     

Group interventions for patients with cancer and HIV disease: Part II. Effects on immune, endocrine, and disease outcomes at different phases of illness

There has been great interest in the potential impact of group interventions on medical outcomes. This article reviews the effects of professionally-led groups on immune activity, neuroendocrine function, and survival among patients with cancer or HIV disease. We examine findings concerning different types of group services at different phases of illness. Results are mixed, but the most prominent changes in immune and endocrine activity were associated with structured group interventions for patients with early-stage disease. These findings offer provocative illustrations of relevant mind-body interactions, but their clinical importance has yet to be demonstrated empirically. Group interventions have not been tied consistently to improved survival rates for patients with advanced cancer; few studies as yet have focused on survival outcomes among patients with early-stage cancer or HIV disease.