XI—Internalising Practical Reasons

Practical reasons figure in both the justification and the causal explanation of action. It is usually assumed that the agent's state of believing rather than what they believe must figure in the causal explanation of action. But, that the agent believes something is not a reason in the sense of being part of the justification of what they do. So it is often concluded that the justifying reason is a different sort of thing from the causally motivating reason. But this means that in a causal process of acting the justifying reasons have done their work by the time the agent has the appropriate beliefs and desires. Transforming these into behaviour is not guided by reason. This conception of action in which there is no role for reason in the part of the process where anything actually gets done is not acceptable. So the original assumption that beliefs rather than the believed facts figure in the causal explanation of action should be challenged.     

Functional and connectivity changes during working memory in Huntington’s disease: 18 month longitudinal data from the IMAGE-HD study

Background

This study aimed to characterize, for the first time, 18 month longitudinal changes in both functional activation and functional connectivity during working memory in premanifest Huntington’s disease (pre-HD) and symptomatic HD (symp-HD).

Methods

Functional magnetic resonance imaging (fMRI) was used to investigate longitudinal changes in neuronal activity during working memory performance via an N-BACK task (0-BACK and 1-BACK) in 27 pre-HD, 17 symp-HD, and 23 control participants. Whole-brain analysis of activation and region-of-interest analysis of functional connectivity was applied to longitudinal fMRI data collected at baseline and 18 months follow-up.

Results

Compared with controls, the pre-HD group showed significantly increased activation longitudinally during 1-BACK versus 0-BACK in the lateral and medial prefrontal, anterior cingulate, primary motor, and temporal areas cortically, and caudate and putamen subcortically. Pre-HD far from onset, compared with controls, showed further longitudinal increases in the right and left dorsolateral prefrontal cortex (DLPFC). Longitudinal increased activation in anterior cingulate and medial primary motor areas were associated with disease burden in the pre-HD group. Moreover, in pre-HD increased activation over time in primary motor and putamen regions were associated with average response time during 1-BACK performance. During 1-BACK, functional connectivity between the right DLPFC and posterior parietal, anterior cingulate, and caudate was significantly reduced over 18 months only in the pre-HD group.

Conclusions

Longitudinal reductions in connectivity over 18 months may represent an early signature of cortico-cortical and cortico-striatal functional disconnectivity in pre-HD, whereas the concomitant increased cortical and subcortical activation may reflect a compensatory response to the demands for cognitive resources required during task performance. Our findings demonstrate that functional imaging modalities have the potential to serve as sensitive methods for the assessment of cortical and subcortical responses to future treatment measures.     

On Shame – In Response to Dan Zahavi,Self and Other

Abstract

In chapter 14 of Zahavi’s recent book, Self and Other, the notion of shame is discussed. In feeling shame one experiences oneself as experienced by others. For Sartre, that experience in itself is sufficient for shame, as one experiences oneself as determined in the experience of others and hence as shamefully not self-determining. But Zahavi introduces an extra condition for shame, which is a ‘global decrease in self-esteem’. This paper questions the need for this condition and argues that seeing oneself as shameful in the eyes of others needs to be spelt out in a pragmatist way in terms of certain shame-involving practices rather than in a purely phenomenological way.     

The Impact of Evidence-Based Practices on Requests for Out-of-Home Placements in the Context of System Reform

Beginning in January 2001 and continuing through April 2008 New Jersey completed statewide implementation of the basic infrastructure of a system of care (SOC) for child and adolescent behavioral health services. In 2008, the state began to enhance its service infrastructure through a large scale implementation of two community-based treatment programs that have been recognized as evidence-based: multisystemic therapy (MST) and functional family therapy (FFT). Multiple evaluations for both therapies have assessed the efficacy of the interventions at the client level. Using interrupted time series analysis, we evaluated the impact of the addition of these new treatment options to New Jersey’s SOC on a system level outcome: statewide requests for out-of-home placements. Results indicate a significant reduction in requests for out-of-home placements associated with the implementation of MST and FFT and a net overall savings to the state.     

How to Stand for Something: Toward a Genealogy of Exemplars

This paper responds to the focus issue on exemplarity that includes contributions by Kyle Lambelet, Brian Hamilton, and Gustavo Maya. The paper calls attention to ancient, medieval, and modern precedents that ought to inform our thinking about the ethical and political significance of exemplars.     

STEMing the tide: using ingroup experts to inoculate women's self-concept in science, technology, engineering, and mathematics (STEM)

Three studies tested a stereotype inoculation model, which proposed that contact with same-sex experts (advanced peers, professionals, professors) in academic environments involving science, technology, engineering, and mathematics (STEM) enhances women's self-concept in STEM, attitudes toward STEM, and motivation to pursue STEM careers. Two cross-sectional controlled experiments and 1 longitudinal naturalistic study in a calculus class revealed that exposure to female STEM experts promoted positive implicit attitudes and stronger implicit identification with STEM (Studies 1-3), greater self-efficacy in STEM (Study 3), and more effort on STEM tests (Study 1). Studies 2 and 3 suggested that the benefit of seeing same-sex experts is driven by greater subjective identification and connectedness with these individuals, which in turn predicts enhanced self-efficacy, domain identification, and commitment to pursue STEM careers. Importantly, women's own self-concept benefited from contact with female experts even though negative stereotypes about their gender and STEM remained active.     

Social Class and Educational Aspirations: A Weberian Analysis

Standard measures of social class are argued to be insufficient in predicting college attendance desires among high school students from similar social class backgrounds. An attitude scale was developed using 274 seniors from two suburban high schools. Chi-square analysis indicates that the attitude measure is a better predictor of college-going plans than is the education of either parent or the occupation of the father. The attitude scale appears to discriminate among students on a dimension similar to McClelland's desire for achievement. It is argued that traditionally static variables, such as social class, can be replaced by process variables in explanations of social phenomena.