The Relationship between Creative Personality Composition,Innovative Team Climate,and Team Innovativeness: An Input — Process — Output Perspective

This study investigates the relationship between creative personality composition, innovative team climate, and team innovation based on an input‐process‐output model. We measured personality with the Creative Person Profile, team climate with the Team Climate Inventory, and team innovation through team‐member and supervisor reports of team innovativeness. The personality composition in each of 29 teams in a television production company was operationalized by mean scores for each creative personality variable, as well as the combination of different creative personality variables within a team. The team climate variable “vision” mediated the relationship between the mean level of associative orientation in teams and team innovation. The team climate variable “support of innovation” mediated the relationship between the joint variables of mean level of ambition x mean level of motivation and team innovation. The results indicated that when there are relationships between creative personality composition and team innovativeness, they are mediated by an innovative team climate.     

Schizotypal and dependent personality characteristics and managerial performance

The study of negatively connotated personality characteristics as predictors of work‐related performance is gaining momentum. While findings have generally suggested such characteristics to be negatively or curvilinearly related to performance, the current study was concerned with investigating any positive relationships that may exist between negatively connotated personality characteristics (as measured by the Hogan Development Survey) and work‐related performance in a sample of 103 Australasian financial services managers. The most notable findings from the study were that: (a) schizotypal personality characteristics positively predicted performance on a creativity competency; and (b) dependent personality characteristics positively predicted performance on a customer focus competency. Findings and limitations are discussed.     

The matching relation and situation-specific bias modulation in professional football play selection

The utility of a quantitative model depends on the extent to which its fitted parameters vary systematically with environmental events of interest. Professional football statistics were analyzed to determine whether play selection (passing versus rushing plays) could be accounted for with the generalized matching equation, and in particular whether variations in play selection across game situations would manifest as changes in the equation's fitted parameters. Statistically significant changes in bias were found for each of five types of game situations; no systematic changes in sensitivity were observed. Further analyses suggested relationships between play selection bias and both turnover probability (which can be described in terms of punishment) and yards-gained variance (which can be described in terms of variable-magnitude reinforcement schedules). The present investigation provides a useful demonstration of association between face-valid, situation-specific effects in a domain of everyday interest, and a theoretically important term of a quantitative model of behavior. Such associations, we argue, are an essential focus in translational extensions of quantitative models.     

The role of histone acetylation in age-associated memory impairment and Alzheimer's disease

Learning and memory are cognitive processes that are tightly regulated. A proper genome-environment interaction is a pre-requisite for cognitive function. Epigenetic processes are central regulators of genome-environment interactions. In line with this, it has been shown that the epigenetic machinery is essential for cognitive function. With a specific focus on histone acetylation, we will discuss recent research in the field of epigenetic mechanisms of learning and memory. We will also specifically address the role of histone acetylation in age-associated memory impairment and Alzheimer's disease and ask the question why targeting the epigenome could be a suitable strategy for neuroprotection and neuroregeneration.     

Early exposure to violence,domestic violence,attachment representations,and marital adjustment

The present study investigates the effects of violent experiences in childhood on current domestic violence and marital adjustment, using adult attachment theory as a conceptual framework. A nonclinical sample of 644 Canadian adults in long‐term romantic relationships completed measures of adult romantic attachment, conflict tactics scales, and dyadic adjustment. Structural equation modeling revealed that early experiences of violence affect adults' intimate violence directly and indirectly through anxiety over abandonment and avoidance of intimacy. The actor–partner interdependence model illustrated the importance of early exposure to violence in predicting both partners' attachment representations, intimate violence, and couple adjustment. Findings are discussed with reference to the clinical issues surrounding minor violence against the intimate partner.     

The anaphase promoting complex is required for memory function in mice

Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior. One of the key pathways mediating protein degradation is proteosomal protein destruction. The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that targets proteins for proteosomal degradation by the 26S proteasome. While the APC/C is essential for cell cycle progression it is also expressed in postmitotic neurons where it has been implicated with axonal outgrowth and neuronal survival. In this study we addressed the role of APC/C in learning and memory function by generating mice that lack the essential subunit APC2 from excitatory neurons of the adult forebrain. Those animals are viable but exhibit a severe impairment in the ability to extinct fear memories, a process critical for the treatment of anxiety diseases such as phobia or post-traumatic stress disorder. Since deregulated protein degradation and APC/C activity has been implicated with neurodegeneration we also analyzed the effect of Apc2 deletion in a mouse model for Alzheimer's disease. In our experimental setting loss of APC2 form principle forebrain neurons did not affect the course of pathology in an Alzheimer's disease mouse model. In conclusion, our data provides genetic evidence that APC/C activity in the adult forebrain is required for cognitive function.