Neurocognitive Effects of Methamphetamine: A Critical Review and Meta-analysis

This review provides a critical analysis of the central nervous system effects of acute and chronic methamphetamine (MA) use, which is linked to numerous adverse psychosocial, neuropsychiatric, and medical problems. A meta-analysis of the neuropsychological effects of MA abuse/dependence revealed broadly medium effect sizes, showing deficits in episodic memory, executive functions, information processing speed, motor skills, language, and visuoconstructional abilities. The neuropsychological deficits associated with MA abuse/dependence are interpreted with regard to their possible neural mechanisms, most notably MA-associated frontostriatal neurotoxicity. In addition, potential explanatory factors are considered, including demographics (e.g., gender), MA use characteristics (e.g., duration of abstinence), and the influence of common psychiatric (e.g., other substance-related disorders) and neuromedical (e.g., HIV infection) comorbidities. Finally, these findings are discussed with respect to their potential contribution to the clinical management of persons with MA abuse/dependence.     

Coping styles and personality: a biometric analysis

Previous research suggests that coping styles are modestly heritable and that this genetic influence is shared in large part with genetic influences on personality. To test this hypothesis, we estimated the heritable basis of the Coping Inventory for Stressful Situations in a sample of 91 monozygotic and 80 dizygotic twin pairs. Task-oriented, emotion-oriented, and social diversion coping styles were modestly heritable (h(2)=.17 to .20), whereas the use of distraction appeared to be influenced solely by environmental factors. Multivariate analyses showed that genetic contributions to coping styles were, at best, only modestly related to genetic contributions to personality (r=-.03 to .35). Environmental contributions to personality were unrelated to environmental factors in coping style. These results suggest that coping style is not merely a manifestation of basic personality traits but does support the possibility that the genetic factors in personality influences have a modest influence on an individual's preferred coping style or strength (e.g., rigidity vs flexibility).     

Reducing aversion to side effects in preventive medical treatment decisions

Laypeople tend to be overly sensitive to side effects of treatments that prevent illness, possibly leading them to refuse beneficial therapies. This Internet-based study attempted to reduce such side effect aversion by adding graphic displays to the numerical risk probabilities. It also explored whether graphics reduce side effect aversion by making it easier for respondents to determine how the treatment might change their net cancer risk. Participants (N=4,248) were presented with a hypothetical preventive treatment situation that was or was not accompanied by a small side effect. In both conditions, the net absolute risk reduction was 12%. Adding an array of stick figures to risk probabilities reduced side effect aversion substantially, but adding a bar graph was not beneficial. The ability of arrays to reduce side effect aversion was not attributable to greater accuracy in evaluating the treatment's net benefit.     

Psychological factors and use of antiepileptic drugs: pilot work using an objective measure of adherence

Given the current emphasis on the "concordance" prescribing model, a study was designed to determine the influence of patients' beliefs about epilepsy, beliefs about medication and a range of neuroepilepsy variables on drug adherence among a sample of epilepsy patients. A special feature of the study was the use of a credible objective measure of drug adherence. Psychological health was also assessed. Thirty-seven patients were recruited from a local epilepsy clinic. Beliefs about epilepsy (illness representations), beliefs about epilepsy medication, anxiety, depression, neuroepilepsy status and adherence were all measured. Data were collected via clinical interview and questionnaire methods. Adherence with drug treatment was determined by an objective measure using low-dose phenobarbital as an indicator of adherence and, or, measurement of antiepileptic drug levels. Neither illness representations nor beliefs about epilepsy drugs were related to adherence. With the exception of time since last seizure, which was positively related to adherence, neuroepilepsy variables were unrelated to adherence. A number of significant associations between cognitive representations of epilepsy and mood were found.     

Distortions in the memory of the pitch of speech

Corneille, Huart, Becquart, & Brédart (2004) found that people remember ambiguous race faces as closer to a race prototype than they actually are. In three studies, we examined whether this memory bias generalizes to voice memory. In Studies 1 and 2, participants listened to synthesized male and female speech samples (high, moderate, or low pitch) and were asked to identify a voice target when paired against distracters higher or lower in pitch. The results showed that pitch distortions occurred, with the pattern consistent with assimilation toward low and high ends of the pitch continuum. Study 3 replicated this result with a wider voice pitch range. The results parallel those of Corneille et al. (2004). The implications of this work are discussed.     

A conjunctive feature similarity effect for visual search

Traditional models of visual search assume interitem similarity effects arise from within each feature dimension independently of other dimensions. In the present study, we examine whether distractor-distractor effects also depend on feature conjunctions (i.e., whether feature conjunctions form a separate “feature” dimension that influences interitem similarity). Spatial frequency and orientation feature dimensions were used to generate distractors. In the bound condition, the number of distractors sharing the same conjunction of features was higher than that in the unbound condition, but the sharing of features within frequency and orientation dimensions was the same across conditions. The results showed that the target was found more efficiently in the bound than in the unbound condition, indicating that distractor-distractor similarity is also influenced by conjunctive representations.     

Beyond change management: a multilevel investigation of contextual and personal influences on employees' commitment to change

The extent to which attitudes toward organizational changes may be affected by contextual (other changes going on) and personal (self-efficacy) factors was investigated with a multilevel design involving 25 different changes. Even after aspects of the change itself were controlled, the interaction between the context and the individual difference explained significant variance in attitudes toward those specific changes. The positive relationship between self-efficacy and commitment to the change was stronger as the amount of simultaneous and overlapping change in the surroundings increased. The implications for research and practice are discussed.     

Empowerment or disempowerment? A review of youth training schemes for non-engaged young people in Hong Kong

This paper investigates the school-to-work experiences of non-engaged youth aged 15-24 who do not participate in education, training, and employment. Based on data from focus groups involving 50 non-engaged young people in Hong Kong, it examines how they are being systematically propelled to the edges of conventional pathways to adulthood, and assesses the efficacy of governmental training schemes that aim to develop employability as a strategy for engaging this population. The paper concludes by outlining prospects for future policy development, focusing on gaps and weaknesses in current provision and practice. It is suggested that effective guidance for non-engaged young people must pay attention to the social context of the individual. Assumptions behind the government's individualistic lifelong learning policy are called into question.