The Curious Tale of Atlas College

Atlas College, a liberal arts institution, was founded during the middle of the nineteenth century. At that time the Board of Trustees adopted as the school's motto the maxim of the Roman poet Juvenal, mens sana in corpore sano, “a sound mind in a sound body.” The saying attracted little notice over the years, but several decades ago a recently appointed member of the board complained at a Trustees' meeting that, while attending a reception to greet members of the faculty, he had found to his dismay that the school's professors were not physically well-conditioned, most appearing either scrawny or corpulent. “How,” he inquired of his fellow Board members, “can these individuals exemplify the ideals of our College, if they fail to display soundness of body?”     

Diagnosis and Assessment of Depression and Suicidality Using the NIMH Diagnostic Interview Schedule for Children (DISC-2.3)

The Diagnostic Interview Schedule for Children (DISC-2.3) was studied in a sample of 265 adolescent inpatients to determine type and concurrent validity of depressive symptoms and depressive disorder diagnoses for different DISC-2.3 informants (parent, adolescent, both). The Children's Depression Rating Scale — Revised, Reynolds Adolescent Depression Scale (RADS), Suicide Ideation Questionnaire — Junior, Spectrum of Suicide Behavior Scale, and clinical consensus diagnoses were used to assess concurrent validity. Results indicated that (1) parents, compared to adolescents, reported a higher prevalence of all depressive symptoms with the exception of weight change; (2) DISC-2.3 depressive and suicidality symptoms were related positively to independent validating criteria for all informant conditions, suggesting good concurrent validity; (3) the DISC-2.3 both informant condition correctly identified the most depressive disorders; and (4) the parent, but not the adolescent, DISC-2.3 Informant condition contributed to the prediction of clinical consensus diagnoses of depression after taking into account RADS scores.     

Attenuation of Hippocampal 11beta-Hydroxysteroid Dehydrogenase Type 1 by Chronic Psychosocial Stress in the Tree Shrew

11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD-1) catalyses the interconversion of active cortisol and corticosterone with inert cortisone and 11-dehydrocorticosterone, thus regulating glucocorticoid access to intracellular receptors. In rats, chronic glucocorticoid excess or stress increases 11beta-HSD-1 in the hippocampus, producing suggestions that it may attenuate the deleterious effects of chronic glucocorticoid excess. However, 11beta-HSD-1 predominantly catalyses 11beta-reduction in the intact liver and hippocampal cells, thus regenerating active glucocorticoids from inert substrate. We studied 11beta-HSD activity in the tissues of male tree shrews following 28 days of sustained psychosocial stress or exogenous administration of cortisol. In the hippocampus, chronic psychosocial stress attenuated 11-HSD-1 activity (69 +/- 9% of control), whereas cortisol alone had no effect. In the liver, both chronic stress and cortisol administration decreased 11beta-HSD-1 activity (47 +/- 11% and 49 +/- 4% fall, resp.). Attenuation of 11beta-HSD-1 within tissues may reflect a homeostatic mechanism designed to minimise the adverse effects of prolonged stress and/or glucocorticoid excess.     

Clinical pragmatism: a method of moral problem solving

This paper presents a method of moral problem solving in clinical practice that is inspired by the philosophy of John Dewey. This method, called "clinical pragmatism," integrates clinical and ethical decision making. Clinical pragmatism focuses on the interpersonal processes of assessment and consensus formation as well as the ethical analysis of relevant moral considerations. The steps in this method are delineated and then illustrated through a detailed case study. The implications of clinical pragmatism for the use of principles in moral problem solving are discussed.     

Developing local lifelong guidance strategies

The background, rationale, methodology and outcomes of a project on developing local lifelong guidance strategies in four areas are outlined. The main components of the strategies developed in the four areas are analysed, and a number of issues relating to the process of strategy development are addressed. Much of the lack of coherence at local level stems from lack of coherence at national policy level: implications for national policy are examined. Finally, implications for parallel work in other localities are explored.     

The specific action of different personality risk factors on cancer of the breast, cervix, corpus uteri and other types of cancer: A prospective investigation

We report the results of a prospective study of a random sample of 1353 elderly but healthy men and women who were followed up for a period of 10 yr, when mortality and cause of death were ascertained. Overall results have been reported elsewhere for mortality from cancer, coronary heart disease and other causes; here we are concerned with the personality factors predicting breast cancer, cervical cancer, cancer of the corpus uteri specifically, as well as other types of cancer in women. Ten specific hypotheses were tested, using specially constructed questionnaires for the purpose, and for most of these statistically significant support was obtained. The results justify belief that specific types of cancer may be related to specific stress/personality factors.     

Power and Personality: An Analysis of Gay Male Intimate Abuse

A study was conducted to investigate the issue of gay male intimate abuse in a sample of 52 couples. The objective of the study was to explore the association between relationship power dynamics and the perpetration of psychological abuse, and to investigate the correspondence between intimate abuse and factors associated with the Abusive Personality [D. G. Dutton and A. J. Starzomski (1993) Borderline Personality in Perpetrators of Psychological and Physical Abuse, Violence and Victims, Vol. 8, pp. 327–337; D. G. Dutton (1994a) Behavioral and Affective Correlates of Borderline Personality Organization in Wife Assaulters, International Journal of Law and Psychiatry, Vol. 17, pp. 265–279.] The majority of participants were middle to upper class and their ethnic/racial breakdown is as follows: White (86%), Native American (7%), Asian (4%), and Other (3%). In terms of power, results indicated that the more frequent form of psychological abuse was significantly higher in relationships characterized by divided power (i.e., partners sharing decision-making authority by the partners each making decisions in different domains). This finding supports the supposition that abuse can occur in relatively egalitarian relationships. An association between intimate abuse and the Abusive Personality was also clearly observed and this personality profile seemed to characterize both members of abusive dyads. Conclusions are drawn regarding the generalizability of intimate abuse across lines of sexual orientation.