Modulation of N400 in chronic non-fluent aphasia using low frequency Repetitive Transcranial Magnetic Stimulation (rTMS)

Low frequency Repetitive Transcranial Magnetic Stimulation (rTMS) has previously been applied to language homologues in non-fluent populations of persons with aphasia yielding significant improvements in behavioral language function up to 43 months post stimulation. The present study aimed to investigate the electrophysiological correlates associated with the application of rTMS through measurement of the semantic based N400 Event-related brain potentials (ERP) component. Low frequency (1 Hz) rTMS was applied to the anterior portion of the homologue to Broca’s area (pars triangularis), for 20 min per day for 10 days, using a stereotactic neuronavigational system. Twelve non-fluent persons with aphasia, 2-6 years post stroke were stimulated. Six participants were randomly assigned to receive real stimulation and six participants were randomly assigned to receive a blind sham control condition. ERP measures were recorded at baseline, 1 week and 2 months subsequent to stimulation. The findings demonstrate treatment related changes observed in the stimulation group when compared to the placebo control group at 2 months post stimulation indicating neuromodulation of N400 as a result of rTMS. No treatment related changes were identified in the stimulation group, when compared to the sham group from baseline to 1 week post stimulation. The electrophysiological results represent the capacity of rTMS to modulate neural language networks and measures of lexical-semantic function in participants with non-fluent aphasia and suggest that time may be an important factor in brain reorganization subsequent to rTMS.     

Adolescent political activism and long-term happiness: a 21-year longitudinal study on the development of micro- and macrosocial worries

Utilizing latent growth modeling, the long-term development of worries among peace movement supporters is examined. Data originate from a seven-wave German longitudinal study started in 1985 with on average 14-year-olds. Waves were interspersed 3 and a half years each. Activists are assumed to have lower (self-related) microworries (Hypothesis 1) and higher macroworries (concerned with larger entities; Hypothesis 2) than nonactivists at the onset of the study. Nonactivists who appraised the threat of nuclear war as high in 1985 are assumed to report worse mental health than their activist age-mates 21 years later (Hypothesis 3). Activists are assumed to express relatively more macroworries than nonactivists in midadulthood (Hypothesis 4). All four hypotheses were confirmed. Results are interpreted in a stress-coping (Lazarus) and resource (Elder) framework, suggesting that refraining from acting out against a perceived sociopolitical threat is a long-term risk for a positive mental health trajectory.     

The use of stereotypes and individuating information in political person perception

This article introduces the political person perception model, which identifies conditions under which perceivers rely on stereotypes (party membership), individuating information (issue position), or both in political person perception. Three studies supported the model's predictions. Study 1 showed that perceivers gave primacy to target information that was narrowly relevant to a judgment, whether that information was stereotypic or individuating. Study 2 found that perceivers relied exclusively on individuating information when it was narrowly relevant to the judgment and relied on both stereotype and individuating information when individuating information was not narrowly relevant to the judgment but did imply a political ideology. Study 3 replicated these findings in a more ecologically valid context and showed that people relied on party information in the absence of narrowly relevant policy positions and when individuating information did not imply a political ideology. Implications for political person perception and theories of stereotyping are discussed.     

Perceiving onset clusters in infancy

By 9-months infants are sensitive to native-language sound combinations. Our studies show that while younger infants discriminate clusters, they are not sensitive to differences in statistical frequency. Thus, the emergence of phonotactic knowledge is driven by experience with the frequency of occurrence of the sound combinations in one's language.     

The Impact of Modifying Interpretive Bias on Contamination-Related Obsessive–Compulsive Symptoms

Cognitive-behavioural models of obsessive–compulsive disorder (OCD) propose that a tendency to negatively interpret ambiguous thoughts and situations plays a key role in maintaining the disorder. Moreover, some researchers have proposed that negative interpretive biases may share a common processing mechanism with attentional biases, with changes in one predicted to lead to changes in the other. The current study examined whether training positive (i.e., adaptive) interpretive bias of contamination-related OCD concerns using a cognitive bias modification paradigm (CBM-I) would lead to reductions in contamination concerns, as well as changes in contamination-related attentional bias. Undergraduate students with high levels of contamination-related OCD symptoms were randomly assigned to receive either positive (n?=?31) or neutral (n?=?33) CBM-I training. Participants in the positive training condition, relative to the neutral training condition, showed a significantly greater increase in positive interpretive bias, significantly less within-session behavioural avoidance of contaminants, and significantly reduced contamination-related cognitions (at one-week follow-up). Contrary to expectations, CBM-I training did not differentially impact attentional bias nor self-reported contamination-related OCD symptoms. We discuss future directions in applying CBM-I to contamination-related OCD.

     

The Role of Parents’ School Climate Perceptions on Attainment Expectations for Black Middle Schoolers

Journal of Child and Family Studies - Parents’ beliefs about their children’s schools are important influences on their parenting and on their children’s outcomes. Because of...     

Methylphenidate Improves Autonomic Functioning among Youth with Attention-Deficit/Hyperactivity Disorder

Research on Child and Adolescent Psychopathology - Psychostimulants are commonly prescribed medications for youth with attention-deficit/hyperactivity disorder (ADHD). Limited studies have...