Stress-induced salivary cortisol secretion during hypobaric hypoxia challenge and in vivo urinary thromboxane production in healthy male subjects

Few studies have assessed the effects of stress on in vivo platelet activation. In the present study, hypobaric hypoxia induced by rapid decompression during high-altitude simulated flight in a hypobaric chamber was used to evaluate the effects of environmental stress on salivary cortisol and urinary thromboxane metabolite (TXM) excretion, a noninvasive marker of in vivo platelet function. Twenty-one male aviators (mean ± SD age = 36 ± 7 years) experiencing hypoxia by removing their oxygen mask for 4-5 min during a simulated flight to 25,000 ft (7,620 m; pO(2) = 59.17 mmHg) and a matched control group of thirteen flying instructors wearing oxygen masks during the challenge, were studied. Hypobaric hypoxia induced a transient significant increase (P < 0.001) in the aviators' salivary cortisol concentration; the overall pattern of diurnal cortisol fluctuation was maintained in both groups. Urinary TXM showed a significant ～30% reduction (P < 0.01) after the chamber session in aviators exposed to hypobaric hypoxia, but not in controls. A significant inverse correlation was found between salivary cortisol and urinary TXM in aviators (r = - 0.64, P = 0.0015). Salivary cortisol was a significant predictor (P < 0.001) for urinary TXM concentrations in aviators. In conclusion, here we observed that an acute stress-induced salivary cortisol increase was associated with reduced urinary thromboxane biosynthesis, providing the first indirect evidence for an inhibitory effect of acute stress on in vivo platelet function.     

Development Projects and Life Satisfaction: An Impact Study on Fair Trade Handicraft Producers

Is there a correspondence between subjective and objective wellbeing indicators in development programs? We investigate this question by evaluating the impact of Fair Trade affiliation on the subjective wellbeing of a sample of Peruvian (treatment and control) producers from two different Fair Trade projects in two socioeconomic environments, one relatively poorer (Juliaca) and the other relatively more affluent (Chulucanas). We find a direct and an indirect effect. The direct effect acts positively via affiliation years in the poorer project and via trade diversification in both projects. The indirect effect acts through the reduction of poverty and relative income. Consistently with the concave income-happiness assumption, the variables generating the indirect effect have a much weaker impact for producers living in the relatively better-off socioeconomic environment, net of the lower FT economic impact in this area.     

Spatial attention and conscious perception: the role of endogenous and exogenous orienting

Attention has often been considered to be a gateway to consciousness (Posner, Proceedings of the National Academy of Sciences of the United States of America, 91(16), 7398–7403, 1994). However, its relationship with conscious perception (CP) remains highly controversial. While theoretical models and experimental data support the role of attention in CP (Chica, Lasaponara, Lupiáñez, Doricchi, &; Bartolomeo, NeuroImage, 51, 1205–1212, 2010; Dehaene, Changeux, Naccache, Sackur, &; Sergent, Trends in Cognitive Sciences, 10, 204–211, 2006; Mack &; Rock, Inattentional blindness, 1998), recent studies have claimed that at least some forms of attention—endogenous or top-down spatial attention—are neither sufficient nor necessary for CP (Koch &; Tsuchiya, Trends in Cognitive Sciences, 11, 16–22, 2007). In the present experiments, we demonstrate the importance of exogenously triggered attention for the modulation of CP. Weak or null effects were instead observed when attention was triggered endogenously. Our data are discussed in the framework of recent neuropsychological models (Dehaene et al., Trends in Cognitive Sciences, 10, 204–211, 2006), postulating that activity within reverberating frontoparietal networks, as colocalized with spatial--orienting systems, is the brain correlate of consciously processed information.     

Development and Validation of Research Scales for the Leadership Multi‐rater Assessment of Personality (LMAP)

This article presents large‐sample developmental and validation research for a set of research scales of an existing 360‐degree personality measure, the LMAP 360 (Leadership Multi‐rater Assessment of Personality). In Study 1 (N = 1,771), we identified 6 broad domains underlying LMAP item clusters: Neuroticism, Dominance, Enthusiasm, Openness, Agreeableness, and Conscientiousness. Scales measuring these broad domains and their constituent facets showed strong internal consistency, inter‐rater reliability, and self‐informant correlations. In Study 2 (N = 729 and N = 694), we examined LMAP research scales’ convergent and discriminant validity against three well‐validated personality inventories (Goldberg's adjectives, the Big Five Inventory, and the Big Five Aspects Scales) and one measure of cognitive ability (the International Cognitive Ability Resource). LMAP research scales correlated strongly with corresponding scales from other inventories and were distinct from cognitive ability.     

The Objection from Cognitive Agreement

Philosophical Studies -     

Nonsuicidal self‐injury across cultures and ethnic and racial minorities: A review

The field of nonsuicidal self‐injury (NSSI) is dominated by research conducted with Caucasian‐majority samples in Western countries such as United States, Canada, Australia and European countries. This article critically reviewed the empirical research on NSSI in non‐Western countries and among ethnic/racial minority individuals who live in the West to give voice to and understand the patterns of NSSI among individuals who do not fall within the dominant Caucasian majority. The study found both similarities and differences between Western and non‐Western data in terms of characteristics and functions of NSSI. Differences in gender patterns in regards to prevalence of NSSI and methods used as well as presence of a more relational functionality of NSSI rather than emotion regulation functionality were two points of divergence in the findings of these studies. In addition, the findings seem to indicate that the role of ethnicity/race is mediated by important factors such as socioeconomic status (SES) and gender. Existing gaps in the literature and suggestions for further research are discussed.     

Ambiguous emotion recognition in temporal lobe epilepsy: The role of expression intensity

The lateralization of emotion processing is currently debated and may be further explored by examining facial expression recognition (FER) impairments in temporal lobe epilepsy (TLE). Furthermore, there is also debate in the literature whether FER deficits in individuals with TLE are more pronounced in the right than in the left hemisphere. Individuals with TLE were tested with an FER task designed to be more sensitive than those classically used to shed light on this issue. A total of 25 right- and 32 left-TLE patients, candidates for surgery, along with controls, underwent an FER task composed of stimuli shown not only at full-blown intensities (100 %), but also morphed to lower-intensity display levels (35 %, 50 %, and 75 %). The results showed that, as compared to controls, right-TLE patients showed deficits in the recognition of all emotional categories. Furthermore, when considering valence, right-TLE patients were impaired only in negative emotion recognition, but no deficits for positive emotions were highlighted in left-TLE patients. Finally, only the right-TLE patients’ impairment was found to be related to the age of epilepsy onset. Our work demonstrates that the FER deficits in TLE span multiple emotional categories and show manifestations dependent on the laterality of the epileptic focus. Taken together, our findings provide the strongest evidence for the right-hemisphere model, but they also partially support the valence model. We suggest that current models are not exhaustive at explaining emotional-processing cerebral control, and further that multistep models should be developed.     

Narcissism, solitude, friendship: notes on the therapeutic alliance in the context of the Freud-Jung relationship

This paper deals with friendship and therapeutic alliance as a transformation of the libidinal love that structures the Oedipal complex. The author considers the relationship between Jung and Freud as a formidable test that may shed light on their personalities and on the relevance of the Oedipal complex for both of them and for their particular theories and practices. The author discusses the possibility that the Oedipal complex may be seen under a finalistic frame of reference and discusses which implicit goals it may express. Such a goal has not been reached by either Freud nor Jung, but might be the key to underline and recognize the fundamental importance of the 'therapeutic alliance' within the analytical situation, seen as a potential relationship between the selves of the patient and of the analyst springing from a transformation of libidinal love into 'friendship' as it was described by Friedrich Nietzsche.     

Ethical recommendations for workers on aggression and predation in animals

The recommendations of a recent workshop (Leiden, Netherlands, November 17–18, 1990) concerning the use of animals in research on aggression and predation are listed. Major considerations included the grade of organisation/level of development of the organism, the duration and intensity of the interaction, post-treatment factors, the number of animals and reuse of animals. It is hoped that the recommendations will help scientists working in these areas to consider the increasingly important ethical dimension.     

On the dimensionality of the System Usability Scale: a test of alternative measurement models

The System Usability Scale (SUS), developed by Brooke (Usability evaluation in industry, Taylor & Francis, London, pp 189–194, 1996), had a great success among usability practitioners since it is a quick and easy to use measure for collecting users’ usability evaluation of a system. Recently, Lewis and Sauro (Proceedings of the human computer interaction international conference (HCII 2009), San Diego CA, USA, 2009) have proposed a two-factor structure—Usability (8 items) and Learnability (2 items)—suggesting that practitioners might take advantage of these new factors to extract additional information from SUS data. In order to verify the dimensionality in the SUS’ two-component structure, we estimated the parameters and tested with a structural equation model the SUS structure on a sample of 196 university users. Our data indicated that both the unidimensional model and the two-factor model with uncorrelated factors proposed by Lewis and Sauro (Proceedings of the human computer interaction international conference (HCII 2009), San Diego CA, USA, 2009) had a not satisfactory fit to the data. We thus released the hypothesis that Usability and Learnability are independent components of SUS ratings and tested a less restrictive model with correlated factors. This model not only yielded a good fit to the data, but it was also significantly more appropriate to represent the structure of SUS ratings.