Short-Term Memory Deficits Are Not Uniform in Down and Williams Syndromes

Neuropsychological investigation of the development of the mnesic function in mental retardation has primarily focused on evaluating short-term memory (STM). Studies have often documented a reduced verbal short-term memory span in individuals with mental retardation and with Down syndrome in particular, compared to groups of mental age-matched controls. However, recent evidence suggests that verbal short-term memory is not equally impaired in all individuals with mental retardation. Findings in children with Williams syndrome are particularly relevant in this regard. Also, data concerning STM for visual information suggest that visual-object and visual-spatial working memory may be differently compromised in people with mental retardation. In particular, individuals with Williams syndrome exhibit specific difficulties in visual-spatial but not in visual-object working memory tasks compared to typically-developing children matched for mental age. Instead, people with Down syndrome show reduced performance in both visual-spatial and visual-object tests. Taken together, these results reinforce the view that intellectual disability is not a unitary condition characterized by homogeneous slowness of cognitive development but a variety of conditions in which some cognitive functions may be more disrupted than others. The finding that the working memory deficit in individuals with Williams and Down syndrome may be qualitatively differentiated also supports the hypothesis that it is not simply a manifestation of general cognitive impairment but, rather, the expression of a specific deficit of a discrete cognitive ability.     

Development of the Lurian Approach: A Cultural Neurolinguistic Perspective

This article presents a discussion of the principle of extracortical organization of higher mental functions and its significance for the development of contemporary neuropsychology. The role of external factors (stimulus-mediator, symbol) in establishing functional connections between various brain systems is, in principle, universal. However, inasmuch as differing mediators and means, or significantly different details within them (direction of writing, orientation by maps or by the behavior of sea birds, etc.) may and in fact do develop in different cultures, neuropsychological analysis must take into account cross-cultural differences. Diagnostic tools must also be adapted to differing cultural contexts. The efficacy of this principle for the analysis of bilingual aphasia and of mental organization of speech, including the effect of acquisition of literacy in native language, is demonstrated. The importance of this principle for the development of new directions in applied neuropsychology is also discussed.     

Crossing the pillars of Hercules: the role of spatial frames of reference in error making

This paper introduces a perspective accounting for errors that may occur as a result of the human interaction with the three-dimensional (3D) space. Particularly, we are interested in errors that are caused by cognitively crossing the boundary between peripersonal and extrapersonal space. Several behavioural, neurophysiological, and neuropsychological perspectives are reviewed in order to develop the theoretical framework on which our ideas are founded. We argue that cognitively crossing the boundary implies switching from one frame of reference to another, which, as a consequence, implies specific costs. The results of five experiments (overall involving 76 participants) support our hypothesis, suggesting the existence of different action-oriented spatial frames of reference.     

Frames and MV-algebras

We describe a class of MV-algebras which is a natural generalization of the class of “algebras of continuous functions”. More specifically, we're interested in the algebra of frame maps Hom (Ω(A), K) in the category T of frames, where A is a topological MV-algebra, Ω(A) the lattice of open sets of A, and K an arbitrary frame. Given a topological space X and a topological MV-algebra A, we have the algebra C (X, A) of continuous functions from X to A. We can look at this from a frame point of view. Among others we have the result: if K is spatial, then C(pt(K), A), pt(K) the points of K, embeds into Hom (Ω(A), K) analogous to the case of C (X, A) embedding into Hom (Ω(A), Ω (X)). 1991 Mathematics Subject Classification: 06F20, 06F25, 06D30 Presented by Ewa Orlowska     

The attentional blink: Resource depletion or temporary loss of control?

Identification of the second of two targets is impaired if it is presented less than about 500 ms after the first. Theoretical accounts of this second-target deficit, known as attentional blink (AB), have relied on some form of limited attentional resource that is allocated to the leading target at the expense of the trailing target. Three experiments in the present study reveal a failure of resource-limitation accounts to explain why the AB is absent when the targets consist of a stream of three items belonging to the same category (e.g., letters or digits). The AB is reinstated, however, if an item from a different category is inserted in the target string. This result, and all major results in the AB literature, is explained by the hypothesis that the AB arises from a temporary loss of control over the prevailing attentional set. This lapse in control renders the observer vulnerable to an exogenously-triggered switch in attentional set.     

Third Men: The Logic of the Sophisms at Arist. SE 22, 178b36–170a10

This article aims at elucidating the logic of Arist. SE 22, 178b36–179a10 and, in particular, of the sophism labelled "Third Man" discussed in it. I suggest that neither the sophistic Walking Man argument, proposed by ancient commentators, nor the Aristotelian Third Man of the , suggested by modern interpreters, can be identified with the fallacious argument Aristotle presents and solves in the passage. I propose an alternative reconstruction of the Third Man sophism and argue that an explanation of the lines regarding the identity of Coriscus and Coriscus the musician (178b39–179a3) is indispensable for its correct understanding, since they hint at another sophism in some important aspects analogous. Finally, I show that two contradictions concerning spotted by scholars in the passage are only apparent and can be dissolved once the assumption that the anti-Platonic Third Man argument is at stake here is discarded, and once the passage is read in the light of its agonistic context.     

Stimulus-dominance effects and lateral asymmetries for language in normal subjects and in patients with a single functional hemisphere

The assessment of language laterality by the dichotic fused-words test may be impaired by interference effects revealed by the dominant report of one member of the stimuli-pair. Stimulus-dominance and ear asymmetry were evaluated in normal population (48 subjects of both sex and handedness) and in 2 patients with a single functional hemisphere. Results show that in normals the number of stimulus-dominated responses is five times higher than in patients, and is negatively correlated to the index of laterality. It is suggested that dichotic stimuli may interfere one with another during the subcortical acoustic processing and at cortical level, when competing for verbal output. Subcortical interference accounts for stimulus-dominance in the single-hemisphere patients. In normal subjects, the dichotic discrimination is disturbed mainly during the hemispheric cross-talk needed for the oral-verbal processing of dichotic inputs. The frequency of 'interhemispheric' interference, as well as the extents of ear asymmetry, may both depend on differences in the processing stage of the competing inputs, and then they may be influenced by differential verbal skills of LH and RH. Very unequal levels of verbal analysis of the dichotic stimuli may hinder reciprocal interference during the hemispheric cross-talk thus yielding large ear asymmetries associated to small dominance effects.     

The role of configurational asymmetry in the lexical access of prefixed verbs: evidence from French

In this paper we investigated the effects of configurational asymmetry in prefixed verbs in French. We used a simple lexical decision paradigm to compare prefixed verbs with external and internal prefixes as specified in linguistic theory (Di Sciullo, 1997) where external prefixes do not change the aktionsart and the verb argument structure of the verb, but internal prefixes do change the aktionsart and may change the verb argument structure of the verb. In Experiment 1 we tested the bi-valent prefix dé- where the configurational difference between external and internal properties of a prefix did not elicit differential response latencies. However, in Experiment 2, where unambiguous prefixes (internal en- and external ré-) were tested, the external prefix elicited longer latencies. These results are discussed with respect to the linguistic constraints the configurational properties of prefixes place upon psycholinguistic models of lexical access, as well as with respect to the effects of prefix bi-valence in the recognition of prefixed verbs.     

Vicarious responses to pain in anterior cingulate cortex: Is empathy a multisensory issue?

Results obtained with functional magnetic resonance imaging show that both feeling a moderately painful pinprick stimulus to the fingertips and witnessing another person’s hand undergo similar stimulation are associated with common activity in a pain-related area in the right dorsal anterior cingulate cortex (ACC). Common activity in response to noxious tactile and visual stimulation was restricted to the right inferior Brodmann’s area 24b. These results suggest a shared neural substrate for felt and seen pain for aversive ecological events happening to strangers and in the absence of overt symbolic cues. In contrast to ACC 24b, the primary somatosensory cortex showed significant activations in response to both noxious and innocuous tactile, but not visual, stimuli. The different response patterns in the two areas are consistent with the ACC’s role in coding the motivational-affective dimension of pain, which is associated with the preparation of behavioral responses to aversive events.     

Autocracy bias in informal groups under need for closure

Two experiments investigated the tendency of groups with members under high (vs. low) need for cognitive closure to develop an autocratic leadership structure in which some members dominate the discussion, constitute the "hubs" of communication, and influence the group more than other members. The first experiment found that high (vs. low) need for closure groups, as assessed via dispositional measure of the need for closure, manifested greater asymmetry of conversational floor control, such that members with autocratic interactional style were more conversationally dominant and influential than less autocratic members. The second experiment manipulated the need for closure via time pressure and utilized a social network analysis. Consistent with expectation, groups under time pressure (vs. no pressure) showed a greater asymmetry of participation, of centrality, and of prestige among the group members, such that the more focal members were perceived to exert the greater influence over the groups' decisions.