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131.
The present research examined the interplay of individual differences in self‐regulatory mechanisms as outlined in regulatory focus theory (promotion‐ and prevention‐focus) and a cue of being watched in the context of cooperative behaviour. Study 1 revealed that the more individuals' habitual self‐regulatory orientation is dominated by a vigilant prevention focus, the more likely they are to act cooperatively (i.e. to donate money to natural conservation organizations) when a subtle cue of being watched renders reputational concerns salient. In contrast, when no such cue is provided individuals' habitual vigilant self‐regulatory orientation is negatively related to cooperative behaviour. Study 2 replicated the results of the initial study and examined interpersonal sensitivity (empathic concern) as a potential mediator of the observed effects. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
132.
Matzel LD Light KR Wass C Colas-Zelin D Denman-Brice A Waddel AC Kolata S 《Learning & memory (Cold Spring Harbor, N.Y.)》2011,18(5):345-356
Learning, attentional, and perseverative deficits are characteristic of cognitive aging. In this study, genetically diverse CD-1 mice underwent longitudinal training in a task asserted to tax working memory capacity and its dependence on selective attention. Beginning at 3 mo of age, animals were trained for 12 d to perform in a dual radial-arm maze task that required the mice to remember and operate on two sets of overlapping guidance (spatial) cues. As previously reported, this training resulted in an immediate (at 4 mo of age) improvement in the animals' aggregate performance across a battery of five learning tasks. Subsequently, these animals received an additional 3 d of working memory training at 3-wk intervals for 15 mo (totaling 66 training sessions), and at 18 mo of age were assessed on a selective attention task, a second set of learning tasks, and variations of those tasks that required the animals to modify the previously learned response. Both attentional and learning abilities (on passive avoidance, active avoidance, and reinforced alternation tasks) were impaired in aged animals that had not received working memory training. Likewise, these aged animals exhibited consistent deficits when required to modify a previously instantiated learned response (in reinforced alternation, active avoidance, and spatial water maze). In contrast, these attentional, learning, and perseverative deficits were attenuated in aged animals that had undergone lifelong working memory exercise. These results suggest that general impairments of learning, attention, and cognitive flexibility may be mitigated by a cognitive exercise regimen that requires chronic attentional engagement. 相似文献
133.
Rhodes R Azzouni J Baumrin SB Benkov K Blaser MJ Brenner B Dauben JW Earle WJ Frank L Gligorov N Goldfarb J Hirschhorn K Hirschhorn R Holzman I Indyk D Jabs EW Lackey DP Moros DA Philpott S Rhodes ME Richardson LD Sacks HS Schwab A Sperling R Trusko B Zweig A 《The American journal of bioethics : AJOB》2011,11(11):1-7
134.
135.
John M Davis William J Giakas Jie Qu Pavan Prasad Stefan Leucht 《Philosophy, ethics, and humanities in medicine : PEHM》2011,6(1):1-13
We reply to the Ioannidis's paper "Effectiveness of antidepressants; an evidence based myth constructed from a thousand controlled trials." We disagree that antidepressants have no greater efficacy than placebo. We present the efficacy from hundreds of trials in terms of the percentage of patients with a substantial clinical response (a 50% improvement or more symptomatic reduction). This meta-analysis finds that 42-70% of depressed patients improve with drug and 21%-39% improve with placebo. The response benefit of antidepressant treatment is 33%-11% greater than placebo. Ioannidis argues that it would be vanishingly smaller because systematic biasing in these clinical trials would reduce the drug-placebo difference to zero. Ioannidis' argument that antidepressants have no benefit is eroded by his failures of logic because he does not present any evidence that there are a large number of studies where placebo is substantially more effective than drug. (To reduce to zero, one would also have to show that some of the unpublished studies find placebo better than drug and have substantial systematic or methodological bias). We also present the empirical evidence showing that these methodological concerns generally have the opposite effect of what Ioannidis argues, supporting our contention that the measured efficacy of antidepressants likely underestimates true efficacy. Our most important criticism is Ioannidis’ basic underlying argument about antidepressants that if the existing evidence is imperfect and methods can be criticized, then this proves that antidepressant are not efficacious. He presents no credible evidence that antidepressants have zero effect size. Valid arguments can point out difficulties with the data but do not prove that a given drug had no efficacy. Indeed better evidence might prove it was more efficacious that originally found. We find no empirical or ethical reason why psychiatrists should not try to help depressed patients with drugs and/or with psychotherapeutic/behavioral treatments given evidence of efficacy even though our treatment knowledge has limitations. The immense suffering of patients with major depression leads to ethical, moral, professional and legal obligations to treat patients with the best available tools at our disposal, while diligently and actively monitoring for adverse effects and actively revising treatment components as necessary. 相似文献
136.
Gruetzmacher N Panzer S Blandin Y Shea CH 《Quarterly journal of experimental psychology (2006)》2011,64(6):1111-1123
An experiment was conducted to determine the coordinate system used in the development of movement codes during observation and utilized on later physical practice performance of a simple spatial-temporal movement sequence. The task was to reproduce a 1.3-s spatial-temporal pattern of elbow flexions and extensions. An intermanual transfer paradigm with a retention test and two transfer tests was used: a mirror transfer test where the same pattern of muscle activation and limb joint angles was required and a nonmirror transfer test where the visual-spatial pattern of the sequence was reinstated on the transfer test. The results indicated a strong advantage for participants in the physical practice condition when transferred to the mirror condition in which the motor coordinates (e.g., pattern of muscle activation and joint angles) were reinstated relative to transfer performance when the visual-spatial coordinates were reinstated (visual and spatial location of the target waveform). The observation group, however, demonstrated an advantage when the visual-spatial coordinates were reinstated. These results demonstrate that codes based in motor coordinates can be developed relatively quickly for simple rapid movement sequences when participants are provided physical practice, but observational practice limits the system to the development of codes based in visual-spatial coordinates. Performances of control participants, who were not permitted to practise or observe the task, were quite poor on all tests. 相似文献
137.
Stefan H?fer Nicole Pfaffenberger Daniela Renn Marion Platter Lena Ring 《Applied research in quality of life》2011,6(1):81-90
To explore potential response shift effects with different quality of life (QoL) instruments in cardiac patients undergoing
coronary intervention. Study Design and Setting: Recalibration was assessed with the disease specific health-related quality
of life (HRQL) instrument MacNew in combination with a then-test approach. Reconceptualisation and reprioritisation were assessed
with the individualised QoL instrument SEIQoL-DW. Significant treatment effects were seen on the MacNew (global Δ: 0.6 ± 1.1,
p = 0.004) but not on the SEIQoL-DW (Δ: 3.3 ± 16, p = 0.37) 6 months after coronary intervention. No recalibration effect was found on the MacNew then-test, while with the SEIQOL-DW
potential response shift effects of reconceptualisation and reprioritisation were seen. For the first time response shift
effects were explored in cardiac patients undergoing coronary intervention. This study confirmed that there is a clinically
significant improvement in disease specific HRQL over time following successful coronary interventions. However, no treatment
effect was seen for individualised QoL with the SEIQoL-DW. This might be due to reconceptualisation and reprioritisation response
effects. Future studies need to focus on exploring response shift effects, and the interrelationship between its different
components, captured by different patient reported outcome instruments in larger patient groups undergoing coronary interventions. 相似文献
138.
Dipl.-Psych. Thomas Schmidt Dr. med. Stefan Lanquillon Dr. phil. Dipl.-Psych. Utz Ullmann 《Forensische Psychiatrie, Psychologie, Kriminologie》2011,5(3):177-183
The value of symptom validity tests in a forensic context is currently the subject of a controversial debate in Germany. The discussion primarily focuses on neuropsychological symptom validity tests, however, tests specific for mental disorders are neglected. Unfortunately, no assessment tools for symptom validation of mental disorders of German origin are available and adaptations of available English state of the art instruments have not yet been tested. Further research of assessment development and qualitative analysis of the decision-making process in medicolegal evaluation is needed in German speaking countries. 相似文献
139.
Rapee RM Kim J Wang J Liu X Hofmann SG Chen J Oh KY Bögels SM Arman S Heinrichs N Alden LE 《Behavior Therapy》2011,42(3):485-492
The current study compared the predicted social and career impact of socially withdrawn and reticent behaviors among participants from Western and East Asian countries. Three hundred sixty-one college students from 5 Western countries and 455 students from 3 East Asian countries read hypothetical vignettes describing socially withdrawn and shy behaviors versus socially outgoing and confident behaviors. Participants then answered questions following each vignette indicating the extent to which they would expect the subject of the vignette to be socially liked and to succeed in their career. Participants also completed measures of their own social anxiety and quality of life. The results indicated significant vignette-by-country interactions in that the difference in perceived social and career impact between shy and outgoing vignettes was smaller among participants from East Asian countries than from Western countries. In addition, significant negative correlations were shown between personal level of shyness and experienced quality of life for participants from both groups of countries, but the size of this relationship was greater for participants from Western than East Asian countries. The results point to the more negative impact of withdrawn and socially reticent behaviors for people from Western countries relative to those from East Asia. 相似文献
140.
We examined the therapeutic efficacy of a culturally adapted form of CBT (CA-CBT) for PTSD as compared to applied muscle relaxation (AMR) for female Latino patients with treatment-resistant PTSD. Participants were randomized to receive either CA-CBT (n = 12) or AMR (n = 12), and were assessed before treatment, after treatment, and at a 12-week follow-up. The treatments were manualized and delivered in the form of group therapy across 14 weekly sessions. Assessments included a measure of PTSD, anxiety, culturally relevant idioms of distress (nervios and ataque de nervios), and emotion regulation ability. Patients receiving CA-CBT improved significantly more than in the AMR condition. Effect size estimates showed very large reductions in PTSD symptoms from pretreatment to posttreatment in the CA-CBT group (Cohen’s d = 2.6) but only modest improvements in the AMR group (0.8). These results suggest that CA-CBT can be beneficial for previously treatment-resistant PTSD in Latino women. 相似文献