Reduced audiovisual integration in synesthesia – evidence from bimodal speech perception

Recent research suggests synesthesia as a result of a hypersensitive multimodal binding mechanism. To address the question whether multimodal integration is altered in synesthetes in general, grapheme‐colour and auditory‐visual synesthetes were investigated using speech‐related stimulation in two behavioural experiments. First, we used the McGurk illusion to test the strength and number of illusory perceptions in synesthesia. In a second step, we analysed the gain in speech perception coming from seen articulatory movements under acoustically noisy conditions. We used disyllabic nouns as stimulation and varied signal‐to‐noise ratio of the auditory stream presented concurrently to a matching video of the speaker. We hypothesized that if synesthesia is due to a general hyperbinding mechanism this group of subjects should be more susceptible to McGurk illusions and profit more from the visual information during audiovisual speech perception. The results indicate that there are differences between synesthetes and controls concerning multisensory integration – but in the opposite direction as hypothesized. Synesthetes showed a reduced number of illusions and had a reduced gain in comprehension by viewing matching articulatory movements in comparison to control subjects. Our results indicate that rather than having a hypersensitive binding mechanism, synesthetes show weaker integration of vision and audition.     

Sexist Behavior Undermines Women’s Performance in a Job Application Situation

Can sexist behavior in a job application context threaten women and cause them to underperform on a subsequent cognitive ability test? In a simulated job interview, 46 women and 46 men -- undergraduate and graduate students from the University of Heidelberg, Germany -- were confronted with either sexist (dominant and physically close) behavior by a male interviewer or non-sexist (friendly and neutral) behavior by the same confederate. Participants then solved math items and language-related items from a German standard intelligence test. In accordance with our hypothesis, the results indicated that female participants in the sexist condition performed significantly worse on the mathematical test than female participants in the control condition. The performance of female participants on the language-related test and male participants on both the math and language-related tests did not differ by experimental condition. After the sexist job interview, women’s impaired performance, occurring on the math items only (i.e., specific to the domain in which women are negatively stereotyped), suggests an influence of psychological and interpersonal processes on seemingly objective test outcomes.     

The anaphase promoting complex is required for memory function in mice

Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior. One of the key pathways mediating protein degradation is proteosomal protein destruction. The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that targets proteins for proteosomal degradation by the 26S proteasome. While the APC/C is essential for cell cycle progression it is also expressed in postmitotic neurons where it has been implicated with axonal outgrowth and neuronal survival. In this study we addressed the role of APC/C in learning and memory function by generating mice that lack the essential subunit APC2 from excitatory neurons of the adult forebrain. Those animals are viable but exhibit a severe impairment in the ability to extinct fear memories, a process critical for the treatment of anxiety diseases such as phobia or post-traumatic stress disorder. Since deregulated protein degradation and APC/C activity has been implicated with neurodegeneration we also analyzed the effect of Apc2 deletion in a mouse model for Alzheimer's disease. In our experimental setting loss of APC2 form principle forebrain neurons did not affect the course of pathology in an Alzheimer's disease mouse model. In conclusion, our data provides genetic evidence that APC/C activity in the adult forebrain is required for cognitive function.     

Mental representations of familiar faces

The Bruce and Young (1986) framework makes a number of important distinctions between the types of representation needed to recognize a familiar face. Here, we return to these, focussing particularly on face recognition units. We argue that such representations need to incorporate idiosyncratic within-person variability, asking questions such as 'What counts as a picture of Harrison Ford?'. We describe a mechanism for achieving this, and discuss the relation between image variability and episodic face memories, in the context of behavioural and neurophysiological data.     

Analysis of sensitive questions across cultures: An application of multigroup item randomized response theory to sexual attitudes and behavior

Answers to sensitive questions are prone to social desirability bias. If not properly addressed, the validity of the research can be suspect. This article presents multigroup item randomized response theory (MIRRT) to measure self-reported sensitive topics across cultures. The method was specifically developed to reduce social desirability bias by making an a priori change in the design of the survey. The change involves the use of a randomization device (e.g., a die) that preserves participants' privacy at the item level. In cases where multiple items measure a higher level theoretical construct, the researcher could still make inferences at the individual level. The method can correct for under- and overreporting, even if both occur in a sample of individuals or across nations. We present and illustrate MIRRT in a nontechnical manner, provide WinBugs software code so that researchers can directly implement it, and present 2 cross-national studies in which it was applied. The first study compared nonstudent samples from 2 countries (total n = 927) on permissive sexual attitudes and risky sexual behavior and related these to individual-level characteristics such as the Big Five personality traits. The second study compared nonstudent samples from 17 countries (total n = 6,195) on risky sexual behavior and related these to individual-level characteristics, such as gender and age, and to country-level characteristics, such as sex ratio. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Linguistic correlates of social anxiety disorder

The goal of this study was to examine the linguistic correlates of social anxiety disorder (SAD). Twenty-four individuals with SAD (8 of them with a generalised subtype) and 21 non-anxious controls were asked to give speeches in front of an audience. The transcribed speeches were examined for the frequency of negations, I-statements, we-statements, negative emotion words, and positive emotion words. During their speech, individuals with either SAD subtype used positive emotion words more often than controls. No significant differences were observed in the other linguistic categories. These results are discussed in the context of evolutionary and cognitive perspectives of SAD.     

Neurobiological correlates of cognitions in fear and anxiety: a cognitive-neurobiological information-processing model

We review likely neurobiological substrates of cognitions related to fear and anxiety. Cognitive processes are linked to abnormal early activity reflecting hypervigilance in subcortical networks involving the amygdala, hippocampus, and insular cortex, and later recruitment of cortical regulatory resources, including activation of the anterior cingulate cortex and prefrontal cortex to implement avoidant response strategies. Based on this evidence, we present a cognitive-neurobiological information-processing model of fear and anxiety, linking distinct brain structures to specific stages of information processing of perceived threat.     

Discriminating famous from fictional names based on lifetime experience: evidence in support of a signal-detection model based on finite mixture distributions

It is widely accepted that signal-detection mechanisms contribute to item-recognition memory decisions that involve discriminations between targets and lures based on a controlled laboratory study episode. Here, the authors employed mathematical modeling of receiver operating characteristics (ROC) to determine whether and how a signal-detection mechanism contributes to discriminations between moderately famous and fictional names based on lifetime experience. Unique to fame judgments is a lack of control over participants' previous exposure to the stimuli deemed "targets" by the experimenter; specifically, if they pertain to moderately famous individuals, participants may have had no prior exposure to a substantial proportion of the famous names presented. The authors adopted established models from the recognition-memory literature to examine the quantitative fit that could be obtained through the inclusion of signal-detection and threshold mechanisms for two data sets. They first established that a signal-detection process operating on graded evidence is critical to account for the fame judgment data they collected. They then determined whether the graded memory evidence for famous names would best be described with one distribution with greater variance than that for the fictional names, or with two finite mixture distributions for famous names that correspond to items with or without prior exposure, respectively. Analyses revealed that a model that included a d' parameter, as well as a mixture parameter, provided the best compromise between number of parameters and quantitative fit. Additional comparisons between this equal-variance signal-detection mixture model and a dual-process model, which included a high-threshold process in addition to a signal-detection process, also favored the former model. In support of the conjecture that the mixture parameter captures participants' prior experience, the authors found that it was increased when the analysis was restricted to names in occupational categories for which participants indicated high exposure.