The harm-benefit tradeoff in "bad deal" trials

This paper examines the nature of the harm-benefit tradeoff in early clinical research for interventions that involve remote possibility of direct benefit and likelihood of direct harms to research participants with fatal prognoses, by drawing on the example of gene transfer trials for glioblastoma multiforme. We argue that the appeal made by the component approach to clinical equipoise fails to account fully for the nature of the harm-benefit tradeoff-individual harm for social benefit-that would be required to justify such research. An analysis of what we label "collateral affective benefits," such as the experience of hope or exercise of altruism, shows that the existence of these motivations reinforces rather than mitigates the necessity of justification by reference to social benefit. Evaluations of social benefit must be taken seriously in the research ethics review process to avoid the exploitation of research participants' motivations of hope or altruism and to avoid the possibility of inadvertent exploitation of high-risk research participants and the harms that would associate with such exploitation.     

“Just another pretty face”: A multidimensional scaling approach to face attractiveness and variability

Findings on both attractiveness and memory for faces suggest that people should perceive more similarity among attractive than among unattractive faces. A multidimensional scaling approach was used to test this hypothesis in two studies. In Study 1, we derived a psychological face space from similarity ratings of attractive and unattractive Caucasian female faces. In Study 2, we derived a face space for attractive and unattractive male faces of Caucasians and non-Caucasians. Both studies confirm that attractive faces are indeed more tightly clustered than unattractive faces in people’s psychological face spaces. These studies provide direct and original support for theoretical assumptions previously made in the face space and face memory literatures.     

Familiar other-race faces show normal holistic processing and are robust to perceptual stress

Other-race individuals are remembered more poorly and receive less holistic/configural processing than same-race individuals, at least when faces are novel. Here, we examine the amelioration of these effects with familiarity, using distinctiveness-matched Caucasian and Asian stimulus sets. We confirmed a cross-race deficit for upright faces following a single encoding trial, which disappeared rapidly with practice on a small set of other-race 'friends' and did not re-emerge when perceptual processing was put under stress (presentation in the periphery). We also examined holistic/configural processing for familiarised faces using the peripheral inversion effect (McKone, 2004 Journal of Experimental Psychology: Learning, Memory, and Cognition 30 181 - 197). A test for faces and nonface objects (dogs) confirmed the validity of this technique as providing a direct measure of holistic processing; we then showed that, after 1 h of training, holistic processing was as strong for other-race as same-race faces. We conclude that practice with other-race individuals can rapidly engage normal face-processing mechanisms.     

Book reviews

Spoehr, K. T., and Lehmkuhle, S. W. Visual Information Processing. San Francisco: Freeman. 1982. Pp. 298. ISBN 0-7167-1373-X. Hardback £16.90; paperback £9.80.

Weale, R. A. Focus on Vision. London: Hodder & Stoughton. 1982. Pp. 194. ISBN 0-340-24839-4. £5.75.

Warren, R. M. Auditory Perception: A New Synthesis. New York: Pergamon Press. 1982. Pp. 239. ISBN 0-08-025957-X. £12.50.

Bryden, M. P. Loterality: Functional Asymmetry in the Intact Brain. London: Academic Press. 1982. Pp. 319. ISBN 0-12-138180-3. £19.60.

Simon, T. W. and Scholes, R. J. (Eds.) Language, Mind, and Brain. Hillsdale, N. J.: Lawrence Erlbaum Associates. 1982. Pp. xvi + 263. ISBN 0-89859-153-8. £19.95.

Wilding, J. M. Perception: From Sense to Object. London: Hutchinson. 1982. Pp. 314. ISBN 0-09-150720-1. £12.95.

Rosenzweig, M.R. and Porter, L. W.(Eds.). Annual Review of Psychology, Vol. 34. Palo Alto, Calif.: Annual Reviews Inc. 1983. Pp. 617. ISBN 0-8243-0234-6. $30.00.

Schank, R. C. Dynamic Memory. Cambridge: Cambridge University Press. 1983. Pp. 233. ISBN 0-521-24856-2. Hardback £18.50; paperback £6.95.

Hinton, G. E. and Anderson, J. A. (Eds.). Parallel Models of Associative Memory. Hillsdale, N. J.: Lawrence Erlbaum Associates. 1981. Pp. 295. ISBN 0-89859-105-0. £17.50.     

Justice for Irregular Migrants,Refugees and Temporary Workers: Some Issues for Carens

The Ethics of Immigration is a wonderfully comprehensive and insightful journey through all the major contemporary ethical issues concerning immigration. Through this outstandingly well‐crafted work, Carens builds a compelling case for many important positions on how we should treat migrants. Nevertheless, I believe there are some tensions in his arguments that could do with more analysis. I present some of these issues in this article. These include some important problems with arguments for the right to education for children of irregular migrants and those concerning admission, his general position on refugees, and his views about what is required in order to treat temporary workers fairly.     

Hybrid Identities and Just Being Yourself

Abstract

This paper points out a tension between Agustín Rayo’s criteria for singulartermhood and his explicit views on the status of Hybrid Identities, that is, identity statements that use singular terms from two different Systems of Representation, such as ‘7=Julius Caesar’ or more suggestively ‘I am b’ where ‘b’ is a singular term referring to my brain. It argues that non-trivial Hybrid Identities are common and important in philosophy and elsewhere, and it suggests a friendly alternative that involves treating Hybrid Identities on the model of Rayo’s ‘Just Is’ statements. The last section of the paper points out that even this friendly alternative has counterintuitive consequences when combined with the metaphysical conventionalism that Rayo finds attractive, when it comes to questions of personal identity over time.     

Hauntings and Healings: Response to Castillo and Cordal

When both therapist and patient have shared the experiences of living in contexts of extreme and continuous trauma, the effects of this will be woven into their relationship and their work together both at a conscious and an unconscious level. This paper explores these effects in the sensitive and insightful case studies presented by Castillo and Cordal as they struggle to come to terms with the aftermath on the dictatorship in Chile. Parallels are drawn with work in South Africa both during and after Apartheid.     

Teaching Genomic Counseling: Preparing the Genetic Counseling Workforce for the Genomic Era

Genetic counselors have a long-standing history of working on the clinical forefront of implementing new genetic technology. Genomic sequencing is no exception. The rapid advancement of genomic sequencing technologies, including but not limited to next generation sequencing approaches, across all subspecialties of genetic counseling mandates attention to genetic counselor training at both the graduate and continuing education levels. The current era provides a tremendous opportunity for counselors to become actively involved in making genomics more accessible, engaging the population in decisions to undergo sequencing and effectively translating genomic information to promote health and well-being. In this commentary, we explore reasons why genomic sequencing warrants particular consideration and put forward strategies for training program curricula and continuing education programs to meet this need.     

Intimate Partner Violence and Subsequent Depression: Examining the Roles of Neighborhood Supportive Mechanisms

This study examines the direct effects of neighborhood supportive mechanisms (e.g., collective efficacy, social cohesion, social networks) on depressive symptoms among females as well as their moderating effects on the impact of IPV on subsequent depressive symptoms. A multilevel, multivariate Rasch model was used with data from the Project on Human Development in Chicago Neighborhoods to assess the existence of IPV and later susceptibility of depressive symptoms among 2959 adult females in 80 neighborhoods. Results indicate that neighborhood collective efficacy, social cohesion, social interactions, and the number of friends and family in the neighborhood reduce the likelihood that females experience depressive symptoms. However, living in areas with high proportions of friends and relatives exacerbates the impact of IPV on females’ subsequent depressive symptoms. The findings indicate that neighborhood supportive mechanisms impact interpersonal outcomes in both direct and moderating ways, although direct effects were more pronounced for depression than moderating effects. Future research should continue to examine the positive and potentially mitigating influences of neighborhoods in order to better understand for whom and under which circumstances violent relationships and mental health are influenced by contextual factors.