Restraint stress and corticotropin releasing hormone modulation of murine cutaneous POMC mRNA

The skin is a unique immunological defense barrier that protects the organism from occupational and environmental exposures and provides a model system in which to evaluate the interaction of the central nervous system with the peripheral immune response. In the studies presented here, we tested mild, acute restraint stress activation of the cutaneous corticotropin releasing hormone-pro-opiomelanocortin (CRH-POMC) axis. We verified that 2 h restraint stress increased the serum concentration of corticosterone and alpha-melanocyte stimulating hormone. We report for the first time that CRH upregulates POMC mRNA expression in mouse skin in vitro. We also demonstrated, by RT-PCR, that 2,4 di-nitrofluorobenzene (DNFB) upregulates cutaneous POMC mRNA expression, the production of which is suppressed by restraint stress. These data confirm the presence and functionality of two hormones of the hypothalamo-pituitary axis in the skin and suggest that activation of the central hypothalamo-pituitary-adrenal axis may over ride activation of the cutaneous CRH-POMC mechanism in the development of DNFB-stimulated allergic contact dermatitis.     

The interpersonal measure of psychopathy: construct and incremental validity in male prisoners

The authors examined the construct and incremental validity of the Interpersonal Measure of Psychopathy (IM-P), a relatively new instrument designed to detect interpersonal behaviors associated with psychopathy. Observers of videotaped Psychopathy Checklist-Revised (PCL-R) interviews rated male prisoners (N = 93) on the IM-P. The IM-P correlated significantly with the PCL-R total score. Moreover, the IM-P was preferentially related to the interpersonal rather than the affective and antisocial lifestyle features of psychopathy. IM-P scores were significantly correlated with age, antisocial behaviors, and self-reported fear, anxiety, and socialization (in reverse). Hierarchical multiple regression analyses demonstrated that although the IM-P exhibited incremental validity beyond the PCL-R total score in detecting self-reported fear, anxiety, and several personality traits, it did not exhibit much incremental validity beyond PCL-R Factor 1. These findings raise questions concerning the unique assessment contribution of the IM-P beyond PCL-R Factor 1. Potential reasons for these findings and alternative means of enhancing the interpersonal assessment of psychopathy are discussed.     

Predicting the suicide attempts of lesbian, gay, and bisexual youth

In this study predictors of serious suicide attempts among lesbian, gay, and bisexual (LGB) youth were examined. Three groups were compared: youth who reported no attempts, youth who reported attempts unrelated to their sexual orientation, and youth whose attempts were considered related to their sexual orientation. About one third of respondents reported at least one suicide attempt; however, only half of the attempts were judged serious based on potential lethality. About half of all attempts were related to youths' sexual orientation. Factors that differentiated youth reporting suicide attempts and those not reporting attempts were greater childhood parental psychological abuse and more childhood gender-atypical behavior. Gay-related suicide attempts were associated with identifiability as LGB, especially by parents. Early openness about sexual orientation, being considered gender atypical in childhood by parents, and parental efforts to discourage gender atypical behavior were associated with gay-related suicide attempts, especially for males. Assessment of past parental psychological abuse, parental reactions to childhood gender atypical behavior, youths' openness about sexual orientation with family members, and lifetime gay-related verbal abuse can assist in the prediction of suicide attempts in this population.     

Test-retest reliability of standard and emotional stroop tasks: an investigation of color-word and picture-word versions

Previous studies have examined the reliability of scores derived from various Stroop tasks. However, few studies have compared reliability of more recently developed Stroop variants such as emotional Stroop tasks to standard versions of the Stroop. The current study developed four different single-stimulus Stroop tasks and compared test-retest reliabilities. The four Stroop tasks included two standard Stroop tasks (color-word and picture-word) as well as two emotional Stroop tasks (color-word and picture-word). The four Stroop tasks were administered on two occasions, separated by 1 week, to 28 undergraduate students. Test-retest reliability coefficients were high for standard and emotional Stroop tasks when reliability was measured using response latencies alone. However, test-retest coefficients were unacceptably low when reliability estimates were calculated using difference scores. The findings have important implications for clinical and experimental use of standard and emotional Stroop tasks.     

Performance differences among four organizational commitment profiles

The authors drew from prior research on organizational commitment and from configural organizational theory to propose a framework of affective and continuance commitment profiles. Using cluster analyses, the authors obtained evidence for 4 of these profiles in an energy industry sample (N=970) and a sample of 345 employed college students. The authors labeled the clusters: allied (i.e., moderate affective and continuance commitment), free agents (moderate continuance commitment and low affective commitment), devoted (high affective and continuance commitment), and complacent (moderate affective and low continuance commitment). Using a subset of the employed student sample (n=148), the authors also found that the free agents received significantly poorer supervisor ratings of performance, organizational citizenship behavior, and antisocial behavior than any other group.     

Factor analyses of the DIB-R in adolescents

The goal of this study was to examine the factor structure of the Revised Diagnostic Interview for Borderlines (DIB-R; Zanarini, Gunderson, Franckenburg, & Chauncey, 1989) in a nonpatient sample of 118 adolescents. A principal components factor analysis with a Varimax rotation extracted three factors. A confirmatory factor analysis showed that this three-factor model provided an adequate fit. The first factor, which included depression, anxiety, helplessness/hopelessness, loneliness/emptiness, and also encompassed odd thinking/unusual perceptive experiences and quasi-psychotic experiences, appeared to be centered on painful feelings and dissociative defense. The second factor, labeled "impulsivity," consisted of impulse action patterns, counterdependency, and stormy relationships. This factor seemed to be centered on defensive acting-out. The third factor, called "aggressiveness," consisted of anger, hypomania, devaluation/manipulation/sadism, and demand/entitlement, and might express manic/narcissistic defenses. These analyses suggest that there may be homogeneous components of borderline symptomatology in adolescents that may reflect affective disturbances and defensive mechanisms.     

The effect of testing procedure on remember-know judgments

Remember-know (R-K) judgments are commonly used to assess conscious recollection of the study episode during recognition. We varied whether participants judged items as R, K, or new (one-step) or first made an old-new judgment and then made the R-K judgment (two-step). The one-step group had a higher R hit rate and K false alarm rate than did the two-step group. In addition, the K responses of the one-step group did not reliably discriminate between old and new items. When a “guess” response category was available, both groups were able to discriminate old and new items using the K response; however, K responses remained more accurate in the two-step condition. R responses appeared to be relatively immune to the effects of testing procedure when the guess category was provided. This suggests that, under some conditions, the R label can reliably indicate a distinct form of recognition memory, suggesting that allowing participants to use a guess response may help them to confine their R-K judgments to confidently recognized items. When participants are not given the option of making a guess response, they may use the R-K distinction to indicate the trace strength of the memory.     

Use of the Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood: Revised Edition (DC:0–3R) with Canadian Infants and Young Children Prenatally Exposed to Substances

The current study examined the mental health diagnostic profiles of infants and young children prenatally exposed to substances using the Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood, Revised (DC:0–3R) diagnostic system. Participants were 46 biological mother–infant dyads who were engaged in a clinical program for mothers with substance‐use problems and their young children (aged 10–41 months). Diagnostic information was reported for each of the five axes listed in the DC:0–3R diagnostic system based on file reviews. In addition, the children's socioemotional and adaptive behaviors were assessed using the Child Behavior Checklist, Infant–Toddler Social Emotional Assessment, the Social‐Emotional Scale, and the Adaptive Behavior Assessment System (2nd ed.). In this sample of young children with prenatal substance exposure, a broad range of socioemotional symptoms were evident, with almost one third of the children meeting criteria for at least one Axis I mental health diagnosis. In addition, the majority of dyads demonstrated features of a disordered relationship. Children in more problematic relationships demonstrated higher levels of socioemotional and adaptive functioning difficulties and were more likely to have an Axis I diagnosis than were children in adapted relationships. The importance of early intervention efforts aimed at infants with prenatal substance exposure and their biological mothers is highlighted, with a particular focus on enhancing the quality of the mother–child relationship.     

Cultural Stereotypes and the Self: A Closer Examination of Implicit Self-Stereotyping

Recent research and theory on implicit self-stereotyping suggests that individuals nonconsciously incorporate stereotypes about their social groups into the self-concept; however, evidence as to whether this holds true for negative stereotypes remains limited. Using a subliminal priming measure, the current research found that women (Experiment 1) and White Americans (Experiment 2) implicitly associated the self with in-group stereotypic traits but not out-group stereotypic traits. Of importance, both groups implicitly self-stereotyped on negative in-group traits to a similar extent as they did on positive in-group traits. Moreover, exploratory analysis showed that the degree to which White Americans associated positive, but not negative, in-group stereotypes with the self was related to higher self-esteem. Implications of implicit self-stereotyping on self-esteem and stereotype-consistent behavior are discussed.     

Long-term Effects of Subliminal Priming on Academic Performance

This research examines the temporal range of subliminal priming effects on complex behavior. In Experiments 1 and 2, participants were subliminally primed with words either related or unrelated to intelligence before completing a practice exam, administered 1 to 4 days before an actual course midterm. Results revealed that the intelligence primes increased performance on the midterm compared to neutral primes. Experiment 1 demonstrated that being told that the priming task was designed to help exam performance moderated the effect of the intelligence primes. In Experiment 2, practice test performance mediated the effect of the primes on midterm performance. These experiments demonstrated that subliminal priming may have long-term effects on real-world behavior, and demonstrates one means by which long-term priming effects may occur.