Mechanism of isoflavone aglycone's effect on cognitive performance of senescence-accelerated mice

This study investigated the effect of isoflavone aglycone (IA) on the learning and memory performance of senescence-accelerated mice, and explored its neural protective mechanism. Results showed that SAM-P/8 senescence-accelerated mice treated with IA performed significantly better in the Y-maze cognitive test than the no treatment control (P<0.05). The cortex AchE activity, serum SOD and GSH-Px activities were notably higher (P<0.05). MDA concentration and the β-secretase activity in the hippocampal tissue were both lower (P<0.05). Additionally, the number of hippocampal neurons was increased and cell morphology was significantly improved. Data suggested that IA could indirectly increase concentration of the cholinergic neural transmitter Ach through regulation of AchE, therefore improving the central cholinergic function and enhancing the learning and memory ability. By reducing the β-secretase activity, IA could decrease the formation and deposition of insoluble Adebris, relieve the resulted toxicity and damage to neurons, and thereby effectively protect the nervous system.     

Examining the Use of Sex to Cope in a Forensic Sample

The authors examined differences between sexual and mentally disordered offenders on the Coping Using Sex Inventory. Sexual offenders were more likely to use sex to cope with negative life events but did not use all forms of deviant sexual activity.     

Correction to: Organizational Benefits of Onboarding Contingent Workers: an Anchoring Model Approach

Journal of Business and Psychology -     

Goal complexes: Integrating achievement goals as standards and self-attributed motives as reasons underlying goal pursuit

Goal complexes, which are formed by pairing standards of competence strivings with their underlying reasons, are essential to an understanding of achievement goal regulation. This paper examines goal complexes that cross other-approach and other-avoidance goals with the approach-avoidance dimensions of Big Three motives as underlying reasons. 220 undergraduates participated in Study 1 which developed and validated the Self-Attributed Motive Scale to measure hope of success, fear of failure, hope of affiliation, fear of rejection, hope of power, and fear of loss of power. Additionally, 235 undergraduates participated in Study 2 where goal complexes were created by crossing the motive items developed in Study 1 with other-approach and other-avoidance goals. The predictive utility of the resultant goal complexes was examined in relation to positive well-being (positive learning-related emotions and engagement), negative well-being (negative learning-related emotions and burnout), and academic buoyancy. The contributions of the studies to the self-attributed motive and goal complex literatures are discussed.

     

Frog embryos use multiple levels of temporal pattern in risk assessment for vibration-cued escape hatching

Animal Cognition - Stereotyped signals can be a fast, effective means of communicating danger, but animals assessing predation risk must often use more variable incidental cues. Red eyed-treefrog,...     

Intentionality and partial belief

Suppose we wish to provide a naturalistic account of intentionality. Like several other philosophers, we focus on the intentionality of belief, hoping that we may later supplement our account to accommodate other intentional states like desires and fears. Now suppose that we also take partial beliefs or credences seriously. In cashing out our favoured theory of intentionality, we may for the sake of simplicity talk as if belief is merely binary or all-or-nothing. But we should be able to supplement or modify our account to accommodate credences. I shall argue, however, that it is difficult to do so with respect to certain causal or teleological theories of intentionality-in particular, those advanced by the likes of Stalnaker (Inquiry, 1984) and Millikan (J Philos 86:281–297, 1989). I shall first show that such theories are tailor-made to account for the intentionality of binary beliefs. Then I shall argue that it is hard to extend or supplement such theories to accommodate credences. Finally, I shall offer some natural ways of modifying the theories that involve an appeal to objective probabilities. But unfortunately, such modifications face problems.     

Neural correlates of inefficient filtering of emotionally neutral distractors from working memory in trait anxiety

Research has indicated that highly trait-anxious (HTA) individuals exhibit a specific deficit in filtering threat-related distractors from visual–spatial working memory (WM). Prior demonstrations of impaired inhibition control in HTA individuals have mainly focused on tasks that required the inhibition of prepotent response tendencies. Studies on the suppression of emotionally neutral distractors from WM in trait anxiety have also been minimal. In this article, we present a study on the manifestation of general inefficient filtering of neutral distractors during visual–spatial WM maintenance stages in HTA individuals. Female participants performed a visual–spatial WM task while event-related potentials were recorded. They were made to remember the orientations of red rectangles within half of the screen and to ignore all salient green rectangles. As predicted, no significant main effect of group and no interaction between group and condition were found in the N2pc component, suggesting that group differences did not manifest in the initial process of object individuation. During the subsequent WM maintenance phase, HTA individuals were highly inefficient at filtering the irrelevant items from WM, as reflected not only by parallel late contralateral delay activity (CDA; 450 to 900 ms) amplitudes for the distractor condition and the four red items, but also by a smaller filtering efficiency score in the HTA group than in the low-trait-anxiety group. Extending previous studies, our findings verify a general filtering impairment in HTA individuals for task-irrelevant salient distractors during a WM maintenance phase.     

Auditory‐motor adaptation is reduced in adults who stutter but not in children who stutter

Previous studies have shown that adults who stutter produce smaller corrective motor responses to compensate for unexpected auditory perturbations in comparison to adults who do not stutter, suggesting that stuttering may be associated with deficits in integration of auditory feedback for online speech monitoring. In this study, we examined whether stuttering is also associated with deficiencies in integrating and using discrepancies between expected and received auditory feedback to adaptively update motor programs for accurate speech production. Using a sensorimotor adaptation paradigm, we measured adaptive speech responses to auditory formant frequency perturbations in adults and children who stutter and their matched nonstuttering controls. We found that the magnitude of the speech adaptive response for children who stutter did not differ from that of fluent children. However, the adaptation magnitude of adults who stutter in response to auditory perturbation was significantly smaller than the adaptation magnitude of adults who do not stutter. Together these results indicate that stuttering is associated with deficits in integrating discrepancies between predicted and received auditory feedback to calibrate the speech production system in adults but not children. This auditory‐motor integration deficit thus appears to be a compensatory effect that develops over years of stuttering.     

Enhancing a Sense of Competence at Work by Engaging in Proactive Behavior: The Role of Proactive Personality

To understand how individuals’ senses of competence are cultivated, scholars have primarily focused on situational factors such as job autonomy and supervisor support. Against this backdrop, we propose that individuals can work as active agents and enhance their sense of competence by initiating actions that aim to master the environment. We adopt the behavioral concordance model and propose that people higher in proactive personality are more likely to engage in proactive behavior that elevates their senses of competence over time. We further propose that such behavioral concordance contributes to boosting a sense of competence is more prominent among those with higher proactive personality. Our predictions are supported by data from 172 employees and their direct supervisors in China, after controlling for the effect of job autonomy and supervisor support for autonomy. Specifically, only those higher in proactive personality engaged in more proactive behavior and increased their sense of competence over time. This study highlights both a self-initiated and a behavioral perspective on understanding the development of a sense of competence.     

The Mystery of Chinese People’s Happiness

The great improvement in economic wealth and social welfare over the decade doesn’t promote the Chinese people’s happiness. We construct a theoretical framework which covers economic wealth, social welfare, individual functional capability to explore the impact factors and determinants of the Chinese people’s happiness. Based on a national wide questionnaire survey in China, we test and modify the framework by the method of structural equation model. The empirical findings indicate that there are direct and indirect effects on the formation of happiness. For the direct effect, both the increasing of economic wealth and social welfare improves the national happiness, while the individual functional capability reduces it. For the indirect effect, the individual functional capability also reduces happiness by negatively affecting economic wealth and social welfare. The negative effect that played by individual functional capability overwhelms the positive effect played by economic wealth and social welfare. This causes the Chinese people’s happiness goes down while the economic wealth and social welfare are improving. Finally, we conclude that the Chinese people’s happiness is more about individual functional capability rather than social welfare or economic wealth.