Prior probability modulates anticipatory activity in category-specific areas

Bayesian models are currently a dominant framework for describing human information processing. However, it is not clear yet how major tenets of this framework can be translated to brain processes. In this study, we addressed the neural underpinning of prior probability and its effect on anticipatory activity in category-specific areas. Before fMRI scanning, participants were trained in two behavioral sessions to learn the prior probability and correct order of visual events within a sequence. The events of each sequence included two different presentations of a geometric shape and one picture of either a house or a face, which appeared with either a high or a low likelihood. Each sequence was preceded by a cue that gave participants probabilistic information about which items to expect next. This allowed examining cue-related anticipatory modulation of activity as a function of prior probability in category-specific areas (fusiform face area and parahippocampal place area). Our findings show that activity in the fusiform face area was higher when faces had a higher prior probability. The finding of a difference between levels of expectations is consistent with graded, probabilistically modulated activity, but the data do not rule out the alternative explanation of a categorical neural response. Importantly, these differences were only visible during anticipation, and vanished at the time of stimulus presentation, calling for a functional distinction when considering the effects of prior probability. Finally, there were no anticipatory effects for houses in the parahippocampal place area, suggesting sensitivity to stimulus material when looking at effects of prediction.     

Weighing the Evidence: A Systematic Review on Long-Term Neurocognitive Effects of Cannabis Use in Abstinent Adolescents and Adults

Findings on neurocognitive effects of sustained cannabis use are heterogeneous. Previous work has rarely taken time of abstinence into account. In this review, we focus on understanding sustained effects of cannabis, which begin when clinical symptoms of the drug have worn off after at least 14 days. We conducted a search between 2004 and 2015 and found 38 studies with such a prolonged abstinence phase. Study-design quality in terms of evidence-based medicine is similar among studies. Studies found some attention or concentration deficits in cannabis users (CU). There is evidence that chronic CU might experience sustained deficits in memory function. Findings are mixed regarding impairments in inhibition, impulsivity and decision making for CU, but there is a trend towards worse performance. Three out of four studies found evidence that motor function remains impaired even after a time of abstinence, while no impairments in visual spatial functioning can be concluded. Functional imaging demonstrates clear differences in activation patterns between CU and controls especially in hippocampal, prefrontal and cerebellar areas. Structural differences are found in cortical areas, especially the orbitofrontal region and the hippocampus. Twenty studies (57 %) reported data on outcome effects, leading to an overall effect size of r _mean?=?.378 (CI 95 %?=?[.342; .453]). Heavy use is found to be more consistently associated with effects in diverse domains than early age of onset. Questions of causality―in view of scarce longitudinal studies, especially those targeting co-occurring psychiatric disorders―are discussed.     

Tender Mercies: Love,Oatmeal, and the Quest for Wholeness

Tender Mercies (1983) is a simple and quiet film that reveals a complexity in its depiction of the many forms love can assume in the soul. Using some of C. G. Jung's and Robert Johnson's observations on the dynamic nature of love, the article tracks the plot of Horton Foote's award-winning screenplay as it unfolds the qualities of love, beginning with romantic love, the most popular form our current culture depicts and promotes, as well as perhaps less glamorous and outwardly exciting forms that nonetheless ground the soul in fuller, more sustainable relations between couples, father and daughter, father and son, as well as the deep passion for what excites and sustains us as creative persons. It also touches on the infernal form of addiction as a kind of fixed and fixated love that harbors no freedom for the individual; an addiction is understood as pornographic to the extent that it continues to promise what it cannot ever deliver, so the individual is always hooked by its fury. By looking closely at various scenes from the film, the author articulates the slow retrieval of one soul from addiction to a life full, whole, and satisfying in its creative and familial love.     

Social influences on unconscious plagiarism and anti-plagiarism

People are more likely to unconsciously plagiarise ideas from a same-sex partner than a different-sex partner, and more likely to unconsciously plagiarise if recalling alone rather than in the presence of their partner [Macrae, C. N., Bodenhausen, G. V., & Calvini, G. (1999). Contexts of cryptomnesia: May the source be with you. Social Cognition, 17, 273–297. doi:10.1521/soco.1999.17.3.273]. Two sets of experiments explore these phenomena, using extensions of the standard unconscious plagiarism paradigm. In Experiment 1A participants worked together in same- or different-sex dyads before trying to recall their own ideas or their partner's ideas. More source errors were evident for same-sex dyads (Experiment 1A), but this effect was absent when participants recalled from both sources simultaneously (Experiment 1B). In Experiment 2A, participants recalled ideas from a single source either alone or in the presence of the partner, using an extended-recall task. Partner presence did not affect the availability of ideas, but did reduce the propensity to report them as task compliant, relative to a partner-present condition. Simultaneous recall from both sources removed this social effect (Experiment 2B). Thus social influences on unconscious plagiarism are apparent, but are influenced by the salience of the alternate source at retrieval.     

Design and operation of an EEG-based brain-computer interface with digital signal processing technology

We are developing an electroencephalographic (EEG)-based brain-computer interface (BCI) system that could provide an alternative communication channel for those who are totally paralyzed or have other severe motor impairments. The essential features of this system are as follows: (1) EEG analysis in real time, (2) real-time conversion of that analysis into device control, and (3) appropriate adaptation to the EEG of each user. Digital signal processing technology provides the speed and flexibility needed to satisfy these requirements. It also supports evaluation of alternative analysis and control algorithms, and thereby facilitates further BCI development.     

Electrophysiological Correlates of Noun–Verb Processing in Adults

Auditory event related potentials (ERPs) were recorded to a series of nouns and verbs while 16 adults watched videotaped scenes. The scenes depicted an individual using objects or performing actions that were either labeled or not named by the auditorily presented nouns or verbs. Electrodes were placed over the left and right hemisphere frontal, temporal, and parietal regions of the scalp. Analyses compared ERPs elicited by words that matched or failed to match the scenes. Marked changes were noted in the ERPs recorded from electrode placements across the two hemispheres in response to words that served two different syntactic functions. This procedure is viewed as a useful technique for use with younger subject populations.     

Multisystemic therapy treatment of substance abusing or dependent adolescent offenders: Costs of reducing incarceration,inpatient, and residential placement

The development of more effective and less costly family- and community-based services to serve as alternatives to out-of-home placements of children is an important priority in the reform of mental health services for children and adolescents. Within the context of a randomized trial with 118 substance abusing or dependent juvenile offenders, we examined the incremental costs of multisystemic therapy (MST) and related these costs to observed reductions in days of incarceration, hospitalization, and residential treatment at approximately 1 year postreferral. Results showed that the incremental costs of MST were nearly offset by the savings incurred as a result of reductions in days of out-of-home placement during the year. The need to validate effective treatments for youth with serious clinical problems and to link the costs of treatment