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41.
The temporal dynamics of consolidation and reconsolidation of taste/odor aversion memory are evaluated during rat pup growth at postnatal days 3, 10, and 18. This is assessed through the temporal gradients of efficacy of a protein synthesis inhibitor (anisomycin) in inducing amnesia after either acquisition (consolidation) or reactivation (reconsolidation). The results show a progressive reduction with age of the delay during which the inhibitor is able to induce amnesia. Control experiments rule out a reduction of anisomycin efficacy due to blood brain barrier growth or decrease in protein synthesis inhibition. Thus, these results present the first evidence that the protein synthesis-dependent phase of memory stabilization requires less time with age. This decrease occurs in parallel for consolidation and reconsolidation. Such changes in the dynamics of memory processing could contribute to the cognitive improvement associated with development.  相似文献   
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The psychometric properties of the d2 Selective Attention Test are analyzed in two samples of premature ( n = 63) and born-at-term ( n = 78) children. The reliability coefficients (internal consistency) reached values of around .90. Principal components analysis revealed a three-factor structure, which accounts for 58% of the variance, and thus coincides with the number of factors presented in the manual of the Spanish adaptation of the test but not with their composition. Results suggest that the d2 test has adequate psychometric properties both for the global sample and for each sub-sample.  相似文献   
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Background/Objective: Ageing and progressive increase in life expectancy in people with intellectual disability present significant challenges. The present study is to examine the needs that arise in the aging process of this population. To detect these needs is fundamental to ensure personal wellbeing; almost no psychometrically sound instruments have been developed. Method: A structured interview was developed and evaluated by a panel of 20 experts to obtain evidence of content validity. The interview was then applied to 1,173 people with intellectual disability. The ages ranged from 35 to 80 (M = 52.27; SD = 7.5). Results: The interview consisted of 93 items evaluating four areas: perceived needs, personal problems, future perspectives, and solutions required. The results demonstrated the proximity and relationship of the various needs evaluated. In addition it was observed that those with intellectual disability who were older, male and users of residential services tended to indicate more needs, problems, and required more solutions. Conclusions: The instrument has adequate evidence of validity, allowing the evaluation of specific needs of people with intellectual disability. The results advocate the design of transversal intervention policies in order to effectively meet the needs and requirements of this population.  相似文献   
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Most deception research provides between-subject results (e.g., liars give on average less detailed accounts), which might be of limited value for professionals evaluating credibility on an individual basis. This study examines the optimal instructions of a within-subject multiple recalls strategy to detect deception. A total of 110 participants, divided into a Lie and Truth group, were randomly placed into four interview conditions: two Basic report-everything instructions (1), a Basic recall followed by an Open depth instruction (2), a Basic recall followed by the Verifiability Approach and Information Protocol (3), and two recalls with the Verifiability Approach and Information Protocol (4). All recalls were coded for total details and verifiable details. Group (lie and truth) × Recall (first and second) was only significant in condition 3, with truth tellers providing more verifiable details in the second recall than the first. A simple within-subject decision rule was derived, allowing a 76.9% discrimination rate. Professionals can optimally evaluate credibility using two recalls (Basic recall followed by Verifiability Approach and Information Protocol) and observing the evolution of verifiable details.  相似文献   
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In two experiments, we investigate hypermnesia, net memory improvements with repeated testing of the same material after a single study trial. In the first experiment, we found hypermnesia across three trials for the recall of word solutions to Socratic stimuli (dictionary-like definitions of concepts) replicating Erdelyi, Buschke, and Finkelstein and, for the first time using these materials, for their recognition. In the second experiment, we had two “yes/no” recognition groups, a Socratic stimuli group presented with concrete and abstract verbal materials and a word-only control group. Using signal detection measures, we found hypermnesia for concrete Socratic stimuli—and stable performance for abstract stimuli across three recognition tests. The control group showed memory decrements across tests. We interpret these findings with the alternative retrieval pathways (ARP) hypothesis, contrasting it with alternative theories of hypermnesia, such as depth of processing, generation and retrieve–recognise. We conclude that recognition hypermnesia for concrete Socratic stimuli is a reliable phenomenon, which we found in two experiments involving both forced-choice and yes/no recognition procedures.  相似文献   
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Two studies were designed to develop and obtain information about the psychometric properties of a shortened 54-item, Spanish version of Ryff's Scales of Psychological Well-being adapted to older people. In Study 1, 267 older people completed the scales, and data were submitted to a principal components analysis. Then, 22 items were selected and grouped into four components (Self-confidence, Orientation to present, Stress, and Social tension) to form the Simplified Ryff's Well-being Scales. In Study 2, the new scales were administered to 107 older people. While internal consistency estimates were similar to those generally obtained for the 54-item scale, results extracted from a confirmatory factor analysis did not support any factorial model. Although the simplified scales can distinguish between conceptually different approaches to well-being, further studies are needed to obtain estimates of reliability and validity.  相似文献   
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Little research has examined how the link between discrimination and cognitive health varies by where people live. This study investigates how living in non-urban versus urban areas in different regions in the United States moderates the discrimination-cognitive health link among older non-Hispanic Blacks. Data are from the 2012 and 2014 waves of the Health and Retirement Study (HRS; N = 2,347). Regression analyses indicate that experiencing more everyday discrimination is significantly associated with lower episodic memory when living in urban areas. Among non-Hispanic Blacks, the discrimination-episodic memory link does not significantly vary across U.S. regional contexts. Findings highlight variation in the association between everyday discrimination and cognitive health by where older non-Hispanic Blacks live. Results suggest the importance of socio-environmental factors in shaping how stressful experiences such as discrimination are linked to cognitive health in later life.  相似文献   
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