Chicks Injected with Antisera to either S-100α or S-100β Protein Develop Amnesia for a Passive Avoidance Task

The cellular expression of S-100β protein is upregulated in Alzheimer's disease and in Down's syndrome, and this protein has been implicated in memory-related processes in laboratory animals. However, the possibility that the α subunit of S-100 is also involved in memory has not yet been examined. In the present study, day-old black Australorp white Leghorn cockerel chicks (Gallus domesticus) received injections of monoclonal antisera to S-100α (1:50) or S-100β (1:500) into each hemisphere immediately after training on a one-trial passive avoidance task. The chicks displayed significantly lower retention levels than control birds that had been injected with antisera to carbonic anhydrase, or with saline (p< .01). S-100α antisera had an amnestic effect when injected between 0 and 20 min after training, with memory deficits occurring from 30 min postlearning, at the point of transition between the A and the B phases of the Gibbs-Ng intermediate memory stage. By contrast, the S-100β antisera needed to be injected either 5 min before or immediately after training and produced amnesia 10 min earlier, at the start of the A phase of the intermediate memory stage. We conclude that the two subunits of the S-100 protein are required at different points in the sequence of events leading to the consolidation of passive avoidance memory.     

Encoding, repetition, and the mirror effect in recognition memory: Symmetry in motion

Attention/likelihood theory has been used to explain the mirror effect in recognition memory. The theory also predicts that any manipulation that affects the recognition of old items will also affect recognition of the new items—more specifically, that all the underlying distributions will move and that they will move symmetrically on the decision axis. In five experiments, we tested this prediction. The first two experiments used encoding tasks during study to change recognition performance for high- and low-frequency words. The results show symmetrical dispersion of the underlying distributions. The final three experiments used repetition to increase recognition performance. Repetition produced a symmetrical pattern of movement that was different from that produced by encoding task. This pattern is, however, also covered by attention/likelihood theory. A further extension of the theory was used to predict response times.     

Compensation for Jaw Fixation by Aphasic Patients

The ability to compensate for fixation of the jaw by a bite block was investigated in 6 nonfluent aphasics, 6 fluent aphasics, and 10 normal control subjects. Acoustic analyses of the vowels [i u a æ] and fricatives [s s] revealed substantial but incomplete compensation for the perturbation in all three subject groups. Perceptual identification scores and quality ratings by naive and phonetically trained listeners indicated poorer identification of the high vowels [i u] under compensatory conditions relative to normal production. Of particular interest was the fact that all three groups of subjects exhibited similar patterns of results. The findings suggest that any deficit in speech motor programming demonstrated by the nonfluent aphasic patients did not affect compensatory abilities. Results are discussed with respect to normal speech adaptation skills and the nature of articulatory breakdown in nonfluent aphasia.     

The Effects of Food and Gender on Interpersonal Perceptions

Male and female subjects provided ratings of personal traits, femininity and masculinity, and total caloric consumption for a female or a male target based on the type of diet she or he had allegedly consumed. The gender associated with the foods presented for each dietary profile was manipulated. Results showed that Target Gender and Dietary Profile significantly affected impression ratings and calorie estimates. Both male and female subjects perceived male eaters and those who ate a feminine diet more favorably. Results are discussed in terms of the different underlying expectations held for males and females when food consumption is involved during the impression formation process.     

A preliminary scale to measure connected and separate knowing: The Knowing Styles Inventory

The present investigation reported the development and validation of the Knowing Styles Inventory (KSI), a scale to measure connected and separate knowing [M. F. Belenky, B. M. Clinchy, N. R. Goldberger, and J. M. Tarule (1986), Women's Ways of Knowing: The Development of Self, Voice, and Mind New York, Basic Books]. In Study 1, principal components analyses for samples of females (N = 300) and males (N = 253) yielded two components, Connected and Separate Knowing. Studies 2 and 3 focused on females exclusively. The results indicated adequate test—retest reliability and internal consistency for both components. Additionally, Connected Knowing was positively correlated with empathic concern, perspective-taking, social desirability, and the femininity factor of the Bem Sex Role Inventory (BSRI). Separate Knowing was positively correlated with the masculinity factor of the BSRI and negatively correlated with social desirability. Suggestions for future research were presented.The authors wish to thank Jill Mattuck Tarule for the insight that she offered in the early stages of this project, and they wish to acknowledge the contribution of Nicole Bressler who participated in item development.     

Grammatical determinants of ambiguous pronoun resolution

Crawley et al. (1990) argue for the primacy of a subject assignment strategy for pronoun assignment during reading, and against the notion of parallel function (Sheldon, 1974). However, most of their items deviated from parallel structure, and none included subject pronouns. In four experiments with subject and nonsubject pronouns, strong parallel function effects emerge when a potential antecedent has the same syntactic role as the pronoun and when the two clauses have the same attachment site and constituent structure. Attachment nonparallelism causes the greatest ambiguity, while the other types lead to more subject assignment overall, although there is always an overlaid parallel function effect. These observations support a model of pronoun assignment according to which potential antecedents are checked for morphological, syntactic and semantic feature matches with the pronoun, and priming/reactivation of syntactic structure across clauses facilitates parallel assignment.This research was supported in part by research grant 410-89-0395 from the Social Sciences and Humanities Research Council of Canada. A preliminary version of the paper was presented at the 1992 meetings of the Canadian Linguistic Association in Charlottetown, Prince Edward Island. I would like to thank Elizabeth Cowper, Keren Rice, Rosemary Stevenson, and an anonymous reviewer for their comments.     

The role of direct-care staff

This article examines the current role of direct-care staff, and their significance to individuals with disabilities living in the community. The role of staff will be redefined with respect to client normalization within the community. Finally, a framework for training staff is provided.     

Resetting the pitch-analysis system: 1. Effects of rise times of tones in noise backgrounds or of harmonics in a complex tone

The question of whether sudden increases in the amplitude of pure-tone components would perceptually isolate them from a more complex spectrum was investigated in two experiments. In Experiment 1, a 3.5-sec noise was played as a masker. During the noise, two pure-tone components of different frequencies appeared in succession. Subjects were asked to judge whether the pitch sequence went up or down. The rise time of these components had only a small and inconsistent effect on discrimination. In Experiment 2, the 3.5-sec background signal was a complex tone. The amplitudes of two of its components were incremented in succession. Again, subjects judged whether the pitch pattern went up or down. This time there was a sizable, monotonic effect of the rise time of the increments, with more rapid increments leading to better discrimination. The difference between the two results is interpreted in terms of the auditory system’s response to changing and unchanging signals and the role of its “sudden-change” responses in attracting perceptual processing to certain spectral regions.     

The relationship between childhood violence and alcohol problems among men who batter: An empirical review and synthesis

The available literature indicates that: (a) experiences of childhood violence are associated with mediator variables, including antisocial behaviors and depressive symptomatology, that are themselves associated with development of alcohol problems and perpetration of partner violence for men in adulthood; (b) experiences of childhood violence and, more strongly, observation of interparental violence during childhood predict perpetration of partner violence in adulthood for males; (c) presence of partner violence is associated with certain types of alcohol problems for men; and (d) both partner violence and alcohol problems are associated with marital conflict. However, available research has often excluded important moderator variables, such as history of familial and parental alcohol problems and history of parental psychiatric disorders. Based on the available research, two indirect pathways between childhood violence and adulthood problems (i.e., alcohol problems and partner violence) are proposed as guides for future research in the areas of family violence and alcohol problems for men. Further, bidirectional associations between alcohol problems and partner violence are proposed. Finally, inclusion of important moderator and mediator variables in multivariate research designs is suggested.