Stress, peer affiliation, and transforming growth factor-beta1 in differentially reared primates

A bidirectional regulatory interaction between the central nervous system and the immune system is largely provided by cytokines and their specific receptors, which are expressed by cells of both systems. Transforming growth factor-beta1 (TGF-beta1), produced by glial cells and lymphocytes and regulated by steroid hormones, is one such cytokine. In the current study, we examined the relationship between TGF-beta1 and peer affiliation in bonnet macaques (Macaca radiata) either reared normally or exposed as infants to conditions in which their mothers faced fluctuating requirements for food procurement (variable foraging demand [VFD]). Rearing under VFD conditions has been previously shown to produce dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in these animals. Serum levels of TGF-beta1 after exposure to a moderate stressor had no correlation with peer affiliation under baseline conditions (r=.07), but were highly correlated with affiliation after subsequent challenge with a fear stimulus (r=.62). Affiliation after the fear stimulus also was inversely correlated with baseline levels of affiliation (r=-.71). These data suggest that changes in peripheral TGF-beta1 may be reflective of latent behavioral and biochemical propensities possibly related to affect. Further examination of the effects of early adversity will improve our understanding of the relationship between the HPA axis and immune function.     

Some Thoughts about the Origins of ``Greek Ethics'

In this paper, I argue that several of the main issues that became a focus for classical Greek philosophy were initially framed by Homer. In particular, Homer identifies a tension between justice and individual excellence, and problematizes the connection between the heroic conception of excellence and ``eudaimonia' (happiness). The later philosophers address the problems raised in Homer by profoundly transforming the way each of these terms was to be conceived.     

Inductive Reasoning in Alzheimer''s Disease

We evaluated knowledge of basic level and superordinate semantic relations and the role of cognitive resources during inductive reasoning in probable Alzheimer's disease (AD). Nineteen mildly demented AD patients and 17 healthy control subjects judged the truthfulness of arguments with a premise and a conclusion that contain familiar concepts coupled with "blank" predicates, such as "Spiders contain phosphatidylcholine; therefore all insects contain phosphatidylcholine." Like healthy control subjects, AD patients were relatively insensitive to the typicality of the premise category when judging the strength of arguments with a conclusion containing a basic-level concept, but were relatively sensitive to typicality during judgments of arguments containing a superordinate in the conclusion. Moreover, AD patients resembled control subjects in judging arguments with an immediate superordinate in the conclusion compared to arguments with a distant superordinate. AD patients differed from control subjects because they could not take advantage of two premises in an argument containing basic-level concepts. We conclude that semantic knowledge is sufficiently preserved in AD to support inductive reasoning, but that limited cognitive resources may interfere with AD patients' ability to consider the entire spectrum of information available during semantic challenges.     

The use of source memory to identify one's own episodic confusion errors

In 4 category cued recall experiments, participants falsely recalled nonlist common members, a semantic confusion error. Errors were more likely if critical nonlist words were presented on an incidental task, causing source memory failures called episodic confusion errors. Participants could better identify the source of falsely recalled words if they had deeply processed the words on the incidental task. For deep but not shallow processing, participants could reliably include or exclude incidentally shown category members in recall. The illusion that critical items actually appeared on categorized lists was diminished but not eradicated when participants identified episodic confusion errors post hoc among their own recalled responses; participants often believed that critical items had been on both the incidental task and the study list. Improved source monitoring can potentially mitigate episodic (but not semantic) confusion errors.     

Test of a potential link between analytic and nonanalytic category learning and automatic, effortful processing

The link between automatic and effortful processing and nonanalytic and analytic category learning was evaluated in a sample of 29 college undergraduates using declarative memory, semantic category search, and pseudoword categorization tasks. Automatic and effortful processing measures were hypothesized to be associated with nonanalytic and analytic categorization, respectively. Results suggested that contrary to prediction strong criterion-attribute (analytic) responding on the pseudoword categorization task was associated with strong automatic, implicit memory encoding of frequency-of-occurrence information. Data are discussed in terms of the possibility that criterion-attribute category knowledge, once established, may be expressed with few attentional resources. The data indicate that attention resource requirements, even for the same stimuli and task, vary depending on the category rule system utilized. Also, the automaticity emerging from familiarity with analytic category exemplars is very different from the automaticity arising from extensive practice on a semantic category search task. The data do not support any simple mapping of analytic and nonanalytic forms of category learning onto the automatic and effortful processing dichotomy and challenge simple models of brain asymmetries for such procedures.     

Distinguishing narcissism and hostility: similarities and differences in interpersonal circumplex and five-factor correlates

Narcissism and hostility are both characterized by dysfunctional social interactions, including tendencies to perceive slights, experience anger, and behave aggressively. The aim of this study was to examine the similarities and differences of narcissism and hostility, using 2 conceptual tools-the interpersonal circumplex and the Five-factor model. In a sample of 292 undergraduate men and women, composite measures of hostility (i.e., Buss-Perry Aggression Questionnaire [Buss & Perry, 1992] and Cook-Medley Hostility [Cook & Medley, 1954] total scores) were inversely correlated with affiliation and unrelated to dominance. In contrast, composite narcissism scores (i.e., Narcissistic Personality Inventory) were positively correlated with dominance and inversely correlated with affiliation. Examination of components of these traits revealed additional similarities and differences, as did associations with other dimensions of the Five-factor model. These findings suggest that the traits of narcissism and hostility are distinguishable by their interpersonal referents, as are their components.     

Children's perceptions of unfair reward and punishment.

Being able to judge the fairness of a personal encounter and having an appreciation of the associated feelings are important components of prosocial development. This study explored a common feature of everyday experience: unfair reward and unfair punishment. Scenarios depicting 4 possible variants of unfairness were read to children aged 9 to 11 years, who then made judgments regarding the degree of unfairness and the nature and strength of the feelings experienced by the characters. Our hypothesis that children with classroom conduct problems would judge the non-receipt of a deserved reward as worse than the receipt of an undeserved punishment was not confirmed. This differentiation, however, did prove to be characteristic of boys in general, but not girls. Being asked to think of unfair things that had actually happened did not appear to influence the children's responses to hypothetical unfair situations, but did reveal that children experience and remember a variety of unfair events in everyday family contexts. This study provides evidence that children actively monitor the receipt of social reward and punishment according to their perception of fairness.     

The Early Marital Roots of Conjugal Distress and Divorce

This article summarizes research that challenges conventional wisdom about the early roots of marital distress and divorce. We abstract results from a 13-year study that focused on the extent to which long-term marital satisfaction and stability could be forecast from newlywed and early marital data. We explore the usefulness of three models emergent distress, enduring dynamics, and disillusionment designed to explain why some marriages thrive and others fail. The dominant paradigm, the emergent-distress model, sees newlyweds as homogeneously blissful and posits that distress develops as disagreements and negativity escalate, ultimately leading some couples to divorce. The results we summarize run counter to this model and suggest instead that (a) newlyweds differ considerably in the intensity of both their romance and the negativity of their behavior toward one another and, for those who remain married, these early dynamics persist over time; and (b) for couples who divorce, romance seems to deteriorate differently depending on how long the marriage lasts. Soon after their wedding, "early exiters" seem to lose hope of improving an unpromising relationship; "delayed-action divorcers" begin marriage on a particularly high note, yet quickly show signs of disillusionment. These delayed-action divorcers reluctantly give up on the marriage long after the romance has faded.