Semantic clustering as a neuropsychological predictor for amnestic-MCI

Recent research has demonstrated that patients with Alzheimer's disease (AD) show deficits in semantic processing when compared to cognitively healthy individuals. This difference is thought to be attributed to losses in higher cortical systems that are predominantly associated with executive functioning. The first aim of the study will be to determine if differences in semantic clustering can accurately differentiate patients with amnestic mild cognitive impairment (aMCI) from cognitively normal (CN) individuals. The second aim will be to determine the extent to which semantic processing might be associated with executive functions. Data from 202 (134 CN, 68 aMCI) participants were analyzed to quantify differences in semantic clustering ratios on the HVLT-R. Study participants ages ranged from 51 to 87 with education ranging from 6 to 20 years. ANCOVA revealed statistically significant differences on semantic clustering ratios (p < .001). Moderate correlations between semantic clustering Category Fluency Test (r = .45) were also found. Statistically significant group differences were also present on Trails-B and WAIS-R Digit Symbol performance (p < .001). Overall, these data indicate that deficits in semantic clustering are present in aMCI patients.     

Conceptual clarity in international collaborations: A point of departure for policy-relevant research on discrimination

A workshop was conducted as part of the International Metropolis Conference held in Vienna, Austria in September 2003. The Metropolis Project is meant to facilitate research in the area of migration that can optimally inform policy. In this context, a workshop was conducted with the objective of discussing how policy-relevant research on discrimination could be conducted internationally. Four broad areas were addressed: ‘key stakeholder’ involvement, obtaining ethical and other forms of approval, international, national and local funding opportunities, and qualitative and quantitative methodology and questionnaire development. Viewpoints represented included those of non-governmental organizations, researchers, health professionals, and policy-makers/implementers. Countries represented in the discussions included Australia, Austria, Canada, Germany, Norway, Sweden, the United Kingdom, and the United States. Key conceptual differences included how best to define discrimination, societal acknowledgement of discrimination, the meaning of ‘race’, ‘racism’, ‘national’, and ‘migrant’, and perceptions of national identity.     

Multiracial recruitment in the field of family therapy: an innovative training program for people of color

This article describes the creation of a training program designed to increase the number of family therapists of color in the family therapy field. In 1992, a partnership between New York City schools of social work, community agencies, and the Ackerman Institute for the Family created the Diversity and Social Work Training Program. Elements critical to the program's success were recruitment strategies, mentorships, partnerships with outside organizations, provision of a long-term institutional commitment, biracial collaborations, and institutional change. This article describes the design, structure, and process of this program's evolution and its impact 12 years later.     

Apolipoprotein E and cognitive performance: a meta-analysis

The epsilon4 allele of the apolipoprotein E (APOE) gene is a known risk factor for Alzheimer's disease and may also affect cognitive performance in normal aging. Evidence of the presence and magnitude of epsilon4-related cognitive deficits was examined with a meta-analysis of the available literature. Thirty-eight studies were included, and cognitive performance was collapsed into 8 domains. Results indicated significant APOE-epsilon4 group differences for global cognitive functioning, episodic memory, and executive functioning, in favor of non-epsilon4 carriers. In addition, older age and APOE-epsilon4 heterozygosity was associated with smaller epsilon4-related impairments. The meta-analysis results suggest that APOE-epsilon4 genotype does affect cognitive performance in healthy aging, although the influence is relatively small and specific to certain domains of cognitive performance.     

Rethinking justice

Changes in the way people marry, bear children and live together, combined with the changing nature of support for families, has put pressure on the justice system to adjust to new family and community realities in order to accomplish justice goals. Although the entire legal system is implicated by the changing nature of families and communities, most scholars and practitioners have focused on the judicial system and those courts most relevant to family issues: namely, the juvenile, family, and criminal courts. As scholars and practitioners began to 'rethink justice,' whole new reform movements of therapeutic jurisprudence, restorative justice, and community justice (among others) have emerged to offer new paradigms for the administration of justice. In this essay we discuss ways in which families and the justice system interact to strengthen and weaken each other to accomplish justice goals.     

Use it or lose it: engaged lifestyle as a buffer of cognitive decline in aging?

Data from the Victoria Longitudinal Study were used to examine the hypothesis that maintaining intellectual engagement through participation in everyday activities buffers individuals against cognitive decline in later life. The sample consisted of 250 middle-aged and older adults tested 3 times over 6 years. Structural equation modeling techniques were used to examine the relationships among changes in lifestyle variables and an array of cognitive variables. There was a relationship between changes in intellectually related activities and changes in cognitive functioning. These results are consistent with the hypothesis that intellectually engaging activities serve to buffer individuals against decline. However, an alternative model suggested the findings were also consistent with the hypothesis that high-ability individuals lead intellectually active lives until cognitive decline in old age limits their activities.     

Tables of d’ for detection and localization

A detection and localization (DAL) procedure (Hershman and Lichtenstein, 1967) is one in which at most one of k noisy observation intervals contains a signal. The observer must detect the signal (if present) and locate it in the proper interval. Tables are given for the extraction of d’ values from the percentage of correct responses made in such experiments.     

Short-term longitudinal change in cognitive performance in later life.

Changes in mean performance on memory, information processing, and intellectual ability tasks over a 3-year period were examined. The sample consisted of 328 community-dwelling men and women (from an original sample of 484 individuals) aged 55-86 years. Ss completed tasks yielding measures of verbal processing time, working memory, implicit memory, vocabulary, verbal fluency, world knowledge, reading comprehension, word recall, and text recall. The results showed significant average decline on working memory, verbal fluency, and world knowledge. There were also interactions for 2 processing time measures and working memory, showing greater decline in the earlier-born cohort group than in the later-born cohort group. A step-down analysis revealed that covarying declines in other variables, including processing time, did not eliminate significant declines in working memory, verbal fluency, and world knowledge.