Intra-amygdala anxiogenic drug infusion prior to retrieval biases rats towards the use of habit memory

In a dual-solution plus-maze task that can be acquired using either hippocampus-dependent "cognitive/place" learning or dorsal striatal-dependent "habit/response" learning, pre-acquisition peripheral or intra-basolateral amygdala (BLA) injections of anxiogenic drugs result in the predominant use of response learning. The present experiments examined the effect of anxiogenic drug treatment on the relative use of multiple memory systems when administered prior to memory retrieval. Adult male Long-Evans rats were trained for two days (6 trials/day, 30s ITI) in a dual-solution plus-maze task to swim from the same start point (south) to an escape platform that was located in a consistent goal arm (west). On day three, prior to a memory retrieval probe trial from a novel start point (north), rats received a peripheral (0.03, 0.1 or 0.3 mg/kg), or intra-BLA (0.1 microg/0.5 microl) injection of the anxiogenic alpha(2)-adrenoreceptor antagonist RS 79948-197, or saline. Relative to saline controls, rats receiving either peripheral or intra-BLA infusions of RS 79948-197 predominantly displayed response learning on the probe trial. In an additional experiment peripheral (0.1 mg/kg) or intra-BLA (0.1 microg) drug injections administered prior to both acquisition and retrieval also resulted in the predominant use of response learning. The findings indicate that (1) similar to acquisition, peripheral injection of an anxiogenic drug prior to memory retrieval biases rats towards the use of habit/response memory, (2) intra-BLA infusions of an anxiogenic drug is sufficient to produce this modulatory effect of emotional state on memory retrieval, and (3) state-dependency does not appear to play a role in the effects of anxiogenic drug treatment on multiple memory system use. The findings may have implications for understanding the interaction between brain function, emotion, and the relative use of multiple memory systems in human psychopathology.     

Memory outcome after pediatric epilepsy surgery: objective and subjective perspectives.

Memory was investigated in 27 children and adolescents in a longitudinal study before and at one and two years after epilepsy surgery. A comparison group with intractable epilepsy (n = 15), matched in age, sex, age of seizure onset, and IQ, was studied at comparable points in time. Methods included administration of standardized measures of story recall and face recognition, and qualitative interviews to probe the participants' perceptions of their memory function over time. There was no significant change over time in either group on the standardized measures. Site and laterality of excision, age at surgery, and seizure outcome were not predictive of change within the surgical group. The narratives revealed facets of memory that were problematic in daily life. The objective and subjective results showed low concordance regarding change, possibly due to limitations in the objective measures for capturing semantic and autobiographical memory.     

Online control of discrete action following visual perturbation

We examined the spatial and temporal limitations of the visual corrective process in goal-directed aiming, as well as gender differences in online control. An initial experiment was conducted to test the utility of a monocular switch procedure as a method of rapidly introducing a visual perturbation. The results revealed minimal effect of the monocular switch on movement time and the endpoint error. Following this control experiment, prismatic displacement was introduced at the initiation of and during the movement. In the third experiment, the prism was presented prior to movement initiation, and then removed at the beginning of or during the movement. Movement trajectories were most influenced by the early presentation and removal of the prism, and female performance was significantly more affected by both perturbations than male performance.     

Church Attendance and Marital Commitment Beliefs of Undergraduate Women

Marital commitment between spouses has been found to be an important predictor of successful marriages. Beliefs about marital commitment among never-married young adults are of interest because of their probable influence on subsequent marital behaviors. The current study examined social-cognitive processes; specifically, religiousness, locus-of-control beliefs, and gender role attitudes, in the prediction of marital commitment beliefs among 294 undergraduate never-married women. We found that higher religiousness and lower chance locus of control were significantly correlated with stronger marital commitment beliefs. Multiple regression analyses revealed that religiousness was the best predictor of marital commitment beliefs in this sample. Social learning processes are implicated in the development of marital commitment beliefs. Implications and limitations of the study are discussed.     

Oscillatory priming and form complexity

Detection of a target grouping is expedited when the target display is preceded by presentation of an oscillating premask that includes priming elements presented intraphasically and below detection threshold at the display locations subsequently occupied by the target. Five experiments were performed to investigate how priming is affected by both the complexity and the geometry of prime/target forms. Experiment 1 showed that the subjective complexity of different polygons was coded in accord with an objective measure of form complexity. Experiments 2 and 3 revealed oscillatory priming to increase as a function of the subjective complexity of prime/target forms when those forms were regular and predictable. However, Experiments 4 and 5 showed that this relation did not hold when the prime/target forms were irregular and unpredictable. Taken together, it is argued that both subjective complexity and the Pr?gnanz quality of the prime/target forms come to determine the magnitude of priming. These results are discussed with reference to current physiological hypotheses regarding perceptual organization.     

Resilient, undercontrolled, and overcontrolled personality prototypes among persons with spinal cord injury

A sample of 199 persons with spinal cord injury (SCI) were assessed on Big Five personality dimensions using the NEO Five-Factor Inventory (NEO-FFI; Costa & McCrae, 1992) at admission to an inpatient medical rehabilitation program. A cluster analysis of the baseline NEO-FFI yielded 3 cluster prototypes that resemble resilient, undercontrolled, and overcontrolled prototypes identified in many previous studies of children and adult community samples. Compared with normative samples, this sample had significantly fewer resilient prototypes and significantly more overcontrolled and undercontrolled prototypes. Undercontrolled individuals were the modal prototype. The resilient and undercontrolled types were better adjusted than the overcontrolled types, showing lower levels of depression at admission and higher acceptance of disability at discharge. The resilient type at admission predicted the most effective reports of social problem-solving abilities at discharge and the overcontrolled type the least. We discuss the implications of these results for assessment and interventions in rehabilitation settings.     

A comparison of laboratory and clinical working memory tests and their prediction of fluid intelligence

The working memory (WM) construct is conceptualized similarly across domains of psychology, yet the methods used to measure WM function vary widely. The present study examined the relationship between WM measures used in the laboratory and those used in applied settings. A large sample of undergraduates completed three laboratory-based WM measures (operation span, listening span, and n-back), as well as the WM subtests from the Wechsler Adult Intelligence Scale-III and the Wechsler Memory Scale-III. Performance on all of the WM subtests of the clinical batteries shared positive correlations with the lab measures; however, the Arithmetic and Spatial Span subtests shared lower correlations than the other WM tests. Factor analyses revealed that a factor comprising scores from the three lab WM measures and the clinical subtest, Letter-Number Sequencing (LNS), provided the best measurement of WM. Additionally, a latent variable approach was taken using fluid intelligence as a criterion construct to further discriminate between the WM tests. The results revealed that the lab measures, along with the LNS task, were the best predictors of fluid abilities.     

Investigating naturalistic decision making in a simulated microworld: What questions should we ask?

Computer-simulated microworlds can provide a controlled method for investigating concepts related to naturalistic decision making (NDM). However, the extent to which these tools can be used to generate meaningful outcomes is unknown. The current study used a microworld called Networked Fire Chief (NFC) to explore the range of skills and knowledge acquired as participants gained practice on the program. The complexity of the NFC NDM environment was also explored. Twenty participants each completed 20 equivalent 5-min scenarios on NFC. Interview data, behavioral data and performance scores were collected across the trials. Results confirmed that NFC provides an environment that promotes appropriate perceptual-cognitive processing for NDM. However, performance improved to only a small extent across the 20 trials in four performance areas: speed, accuracy, efficiency and planning. In addition, the number of personal and situational factors to be considered when decision making on NFC was not comparable with real-world NDM environments. Overall, results indicated that the use of microworlds for research should be regulated by an understanding of the limitations of their applicability.     

Communal Behaviors and Psychological Adjustment of Family Caregivers and Persons With Spinal Cord Injury

OBJECTIVE: Examined the influence of mutual communal behaviors on the adjustment reported by persons with spinal cord injury (SCI) and their family caregivers. Previous research has found that persons who have a history of mutually communal behaviors in relationships may react differently to relationship changes after an acquired physical disability than dyads with few communal behaviors. METHOD: Family caregivers and persons with SCI were administered measures of mutual communal behaviors, depression, and life satisfaction. Structural equation modeling was used to test the relations among caregivers' communal behaviors and care recipients' communal behaviors, depression, and life satisfaction. RESULTS: Caregiver and care recipient reports of communal behaviors were not significantly correlated. Significant paths indicated that care recipients' communal behavior scores were positively associated with their life satisfaction, and care recipients' depression was inversely associated with their life satisfaction. Caregivers' communal behavior scores were unrelated to their self-reported adjustment. CONCLUSIONS: Caregiver-care recipient dyads may differ in their perceptions of communal behaviors in their relationships. Although care recipient reports of communal behavior may be related to their life satisfaction, communal behaviors may not serve a similar function among caregivers of persons with SCI.