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21.
Alternation behavior, spatial discrimination, and reversal disturbances following 6-hydroxydopamine lesions in the nucleus accumbens of the rat 总被引:3,自引:0,他引:3
K Taghzouti A Louilot J P Herman M Le Moal H Simon 《Behavioral and neural biology》1985,44(3):354-363
The effects of dopaminergic depletion of the nucleus accumbens was tested in various behavioral tasks such as alternation, spatial discrimination, and reversal learning, and in an extinction paradigm in a T maze. Animals with lesions showed impairment of spontaneous alternation behavior, disturbances in the acquisition of spatial discrimination, and great difficulty in reversing previously learned habits. In the extinction phase, experimental animals are unable to adjust their behavior, and continue to choose the previously reinforced arm of the T maze. It is suggested that the nucleus accumbens plays an important role in the transition of motivation into action, and that dopamine has a facilitatory influence on the mediation of these processes. 相似文献
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M J Simon 《Journal of personality assessment》1985,49(4):437-439
An attempt was made to test the hypothesis that the Egocentricity Index (Exner, 1974), a ratio which incorporates pair and reflection responses, is related to self-esteem. Sixty criminal defendants referred for psychiatric evaluation were routinely administered the Rorschach. After all other testing was completed the subjects were asked to complete the Coopersmith Self-esteem Inventory. Results found no significant relationships between the Egocentricity Index and self-esteem as measured by the Coopersmith. It was recommended that the Egocentricity Index not be used as a measure of self-esteem until research evidence to support its use in this manner is provided. 相似文献
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Most of the empirical literature on juvenile homicide has emerged from the clinical experience of mental health professionals who have diagnosed and/or treated youngsters who killed. After a critical review of this literature, data on 787 juvenile homicide offenders are presented and discussed. These data indicate that intrafamilial killings represent but a small fraction of all homicides perpetrated by juveniles and that there are clear differences between intrafamilial and extrafamilial juvenile homicides. 相似文献
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Disturbances in exploratory behavior and functional recovery in the Y and radial mazes following dopamine depletion of the lateral septum 总被引:1,自引:0,他引:1
The effects of 6-hydroxydopamine (6-OHDA) injected into the lateral septum in rats were investigated for spontaneous alternation behavior in a Y maze and for spatially oriented behavior in an 8-arm radial maze. The performance of the animals in these tests was assessed under two physiological states, food-satiated and food-deprived. The selective depletion of septal dopaminergic concentrations leads to behavioral disturbances in both the Y and the radial mazes. These deficits disappeared when the animals with 6-OHDA lesions were food-deprived. These results confirm other studies from our laboratory and support two conclusions. First, lesions of dopaminergic neurons lead to behavioral impairments which resemble those found after the total lesion of the structure they innervate. Second, these behavioral impairments are responsive to therapeutic treatments, manipulations of the internal or external environment, or the level of arousal, since under certain conditions a recovery of function can occur in the absence of dopaminergic neurons. These two points provide additional support for a nonspecific role for the dopaminergic neurons originating in the ventral tegmental area. These neurons could have a permissive role in the functioning of the forebrain structures they innervate. 相似文献
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The use of sacrificial animal blood in the Hebrew Bible has generated much discussion. While various scholars have attempted to explain the significance of these blood rites, each of these attempts has proved problematic. The current paper employs mimetic theory to develop a more robust and plausible model for exploring biblical animal sacrifice. Using the Passover ritual as a model, I develop a model of sacrificial blood rites as pantomimes of mimetic violence. These pantomimes re-create a violent yet transformative crisis from the community's collective memory. Such rituals allow the community to enter into and re-experience the cleansing violence of a mimetic crisis, albeit in a more controlled manner. Through these pantomimes, the community attempts to appease the primitive sacred's blood lust and re-discover the divine blessing secured through the original crisis. This model may prove helpful when applied to more opaque examples of biblical blood manipulation. 相似文献
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不良的亲子依恋是导致儿童抑郁症状的风险因素,但其对儿童的影响会因儿童对环境的生物敏感性不同而存在差异。为探究家庭中母子、父子依恋对儿童抑郁症状的影响及儿童生物敏感性(本文中采用迷走神经抑制作为指标)在其中的作用,本研究结合行为任务、问卷报告、生理测量等多种研究手段,招募150名学龄儿童(平均年龄8.64岁,63名女孩)参与研究。结果表明:(1)学龄儿童的母子依恋水平高于父子依恋水平。(2)高水平的母子依恋与父子依恋会同等程度地降低儿童的抑郁症状。(3)儿童对环境的生物敏感性对母子依恋影响儿童抑郁症状路径的调节作用显著,生理上对环境更敏感(高迷走神经抑制)的儿童更易得益于高母子依恋,表现出较低的抑郁水平;但同时,这类儿童在母子依恋较低时也更易表现出较高的抑郁水平。(4)儿童的生物敏感性对父子依恋影响儿童抑郁症状路径的调节作用不显著,高父子依恋对生物敏感性水平不同的儿童均存在有利影响。(5)在不同情境中测量的迷走神经抑制对亲子依恋影响儿童抑郁症状的调节作用模式相似,表现出跨情境一致的特点。本研究率先揭示儿童迷走神经抑制与亲子依恋对儿童抑郁症状的联合作用机制及父母角色差异。 相似文献
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