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31.
Disturbances in exploratory behavior and functional recovery in the Y and radial mazes following dopamine depletion of the lateral septum 总被引:1,自引:0,他引:1
The effects of 6-hydroxydopamine (6-OHDA) injected into the lateral septum in rats were investigated for spontaneous alternation behavior in a Y maze and for spatially oriented behavior in an 8-arm radial maze. The performance of the animals in these tests was assessed under two physiological states, food-satiated and food-deprived. The selective depletion of septal dopaminergic concentrations leads to behavioral disturbances in both the Y and the radial mazes. These deficits disappeared when the animals with 6-OHDA lesions were food-deprived. These results confirm other studies from our laboratory and support two conclusions. First, lesions of dopaminergic neurons lead to behavioral impairments which resemble those found after the total lesion of the structure they innervate. Second, these behavioral impairments are responsive to therapeutic treatments, manipulations of the internal or external environment, or the level of arousal, since under certain conditions a recovery of function can occur in the absence of dopaminergic neurons. These two points provide additional support for a nonspecific role for the dopaminergic neurons originating in the ventral tegmental area. These neurons could have a permissive role in the functioning of the forebrain structures they innervate. 相似文献
32.
The use of sacrificial animal blood in the Hebrew Bible has generated much discussion. While various scholars have attempted to explain the significance of these blood rites, each of these attempts has proved problematic. The current paper employs mimetic theory to develop a more robust and plausible model for exploring biblical animal sacrifice. Using the Passover ritual as a model, I develop a model of sacrificial blood rites as pantomimes of mimetic violence. These pantomimes re-create a violent yet transformative crisis from the community's collective memory. Such rituals allow the community to enter into and re-experience the cleansing violence of a mimetic crisis, albeit in a more controlled manner. Through these pantomimes, the community attempts to appease the primitive sacred's blood lust and re-discover the divine blessing secured through the original crisis. This model may prove helpful when applied to more opaque examples of biblical blood manipulation. 相似文献
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Herbert A. Simon 《Psychometrika》1962,27(4):417-418
It is shown that a rational learning curve developed by Estes for paired associate learning is a special case of a more general function. The latter is the product of two functions and assumes that the discovery and fixation aspects of learning are independent. The indications are that the form of one of the functions has not been tested sharply by Estes in the paired associate learning setting. 相似文献
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Lora S. Simon 《Journal of counseling and development : JCD》1967,45(10):973-978
The “disjuncture” between level of aspiration and means of accomplishing it can create serious difficulty for the person. The function of the 2-year college in helping the student to resolve this conflict has been described as a “cooling-out” process. Essentially, it involves a running evaluation of the student's capacities, and guidance in helping him to find the educational and vocational program for which he is best suited. Several ways of facilitating this process are presented. There is need for an integrated guidance program pervading the entire institution as well as the student's career at the institution. 相似文献
38.
Motivational and emotional controls of cognition 总被引:9,自引:0,他引:9
H A Simon 《Psychological review》1967,74(1):29-39
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Simon Grondin 《Attention, perception & psychophysics》1993,54(3):383-394
Experiments 1 and 2 compared, with a single-stimulus procedure, the discrimination of filled and empty intervals in both auditory and visual modalities. In Experiment 1, in which intervals were about 250 msec, the discrimination was superior with empty intervals in both modalities. In Experiment 2, with intervals lasting about 50 msec, empty intervals showed superior performance with visual signals only. In Experiment 3, for the auditory modality at 250 msec, the discrimination was easier with empty intervals than with filled intervals with both the forced-choice (FC) and the single stimulus (SS) modes of presentation, and the discrimination was easier with the FC than with the SS method. Experiment 4, however, showed that at 50 and 250 msec, with a FC-adaptive procedure, there were no differences between filled and empty intervals in the auditory mode; the differences observed with the visual mode in Experiments 1 and 2 remained significant. Finally, Experiment 5 compared differential thresholds for four marker-type conditions, filled and empty intervals in the auditory and visual modes, for durations ranging from .125 to 4 sec. The results showed (1) that the differential threshold differences among marker types are important for short durations but decrease with longer durations, and (2) that a generalized Weber’s law generally holds for these conditions. The results as a whole are discussed in terms of timing mechanisms. 相似文献