Paul N. Pfeiffer MD  Hyungjin M. Kim ScD  Dara Ganoczy MPH  Kara Zivin PhD  Marcia Valenstein MD 《Suicide & life-threatening behavior》2013,43(4):356-365

We evaluated whether treatment‐resistant depression (TRD) as measured by the Massachusetts General Hospital (MGH) staging method was associated with suicide in a large U.S. health system. Data from the Veterans Health Administration and the National Death Index were used to conduct a case–control study of patients newly diagnosed with depression who received antidepressant treatment between 2003 and 2006. Suicide cases (N = 499) were matched with nonsuicide controls (N = 1994). Conditional logistic regression was used to assess whether MGH stage at time of suicide (or matched date) was associated with case status, adjusting for patient demographic characteristics, comorbidity, and service use. Results indicated 11.6% of suicide cases had MGH stage 3 or greater (indicating at least two antidepressant trials) compared to 6.4% of controls (p < .001). In adjusted analyses, suicide was not significantly more likely among patients with stage 3 or greater (OR 1.52; 95% CI: 0.98, 2.37) or stages 1.5–2.5 (OR 1.19; 95% CI: 0.91, 1.55) compared to patients with stage 1 or less (<10 weeks of antidepressant medication). Staging TRD using MGH criteria is unlikely to substantially improve suicide risk assessment of depressed patients beyond existing measures contained in health system records.  相似文献   

    

Sverre Varvin MD  Dr Philos 《The International journal of psycho-analysis》2013,94(3):431-435

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Drs. Diana E. Clarke PhD  William W. Eaton PhD  Kenneth R. Petronis Phd  Jean Y. Ko PhD  Anjan Chatterjee MD  MPH  Dr. James C. Anthony PhD 《Suicide & life-threatening behavior》2010,40(4):307-318

The incidence rate of suicidal ideation among current and former smokers versus never smokers is not known. In this study, the age‐adjusted incidence of suicidal ideation was highest among current smokers, followed by former, then never smokers. The adjusted hazard for suicide ideation was 2.22 (95%CI = 1.48, 3.33) and 1.19 (95%CI = 0.78, 1.82) for current and former smokers, respectively, compared to never smokers. Results indicate that current smokers have increased risks of suicidal ideation above and beyond the risk for never and former smokers regardless of age, gender, history of depressive disorder or anxiety symptoms, and alcohol abuse/dependence. Smoking cessation might be beneficial for some suicide prevention efforts.  相似文献   

    

Kirsten Windfuhr PhD  Harriet Bickley BA  David While PhD  Alyson Williams PhD  Isabelle M. Hunt PhD  Louis Appleby MD  FRCPsych  Navneet Kapur MD  FRCPsych 《Suicide & life-threatening behavior》2010,40(2):151-158

Little is known about the numbers and characteristics of people who travel away from home before dying by suicide. Therefore, this studied attempts to identify the sociodemographic characteristics, location, and method of suicide in people who died distant from home, in a national sample. Data were collected on all English suicides and a patient population; nonresident suicides resided in one Health Authority but died in a different one. Twelve percent of suicides were nonresident and features of these included: young age, social adversity, and severe mental illness. In conclusion, both individual‐ and area‐based factors are likely to contribute to suicide away from home.  相似文献   

    

Richard Zimmer MD 《The International journal of psycho-analysis》2012,93(6):1519-1524

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Kenneth R. Conner PsyD  MPH  Michael D. McCarthy PhD  Alina Bajorska MA  Eric D. Caine MD  Xin M. Tu PhD  Kerry L. Knox PhD 《Suicide & life-threatening behavior》2012,42(6):699-708

There are meager prospective data from nonclinical samples on the link between anxiety disorders and suicide or the extent to which the association varies over time. We examined these issues in a cohort of 309,861 U.S. Air Force service members, with 227 suicides over follow‐up. Mental disorder diagnoses including anxiety, mood, and substance‐use disorders (SUD) were based on treatment encounters. Risk for suicide associated with anxiety disorders were lower compared with mood disorders and similar to SUD. Moreover, the associations between mood and anxiety disorders with suicide were greatest within a year of treatment presentation.  相似文献   

    

Howard B. Levine MD 《The International journal of psycho-analysis》2011,92(1):235-240

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Karolina Krysinska PhD  Graham Martin MD 《Suicide & life-threatening behavior》2009,39(5):548-557

Population attributable risk (PAR) estimates have been used in suicide research to evaluate the impact of psychosocial and socioeconomic risk factors, including affective disorders, traumatic life events, and unemployment. A parallel concept of preventive fraction (PF), allowing for estimation of the impact of protective factors and effectiveness of preventive interventions, is practically unknown in suicidology. The study authors discuss the application of both concepts to suicide research and prevention, and review literature on the subject. Despite several methodological and conceptual limitations, both PAR and PF are valuable instruments to inform development and evaluation of suicide prevention programs.  相似文献   

    

Richard M. Waugaman MD 《The International journal of psycho-analysis》2016,97(5):1467-1471

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Matthew K. Nock PhD  Robert J. Ursano MD  Steven G. Heeringa PhD  Murray B. Stein MD  MPH  Sonia Jain PhD  Rema Raman PhD  Xiaoying Sun MS  Wai Tat Chiu AM  Lisa J. Colpe PhD  MPH  Carol S. Fullerton PhD  Stephen E. Gilman ScD  Irving Hwang MA  James A. Naifeh PhD  Anthony J. Rosellini PhD  Nancy A. Sampson BA  Michael Schoenbaum PhD  Alan M. Zaslavsky PhD  Ronald C. Kessler PhD  the Army STARRS Collaborators 《Suicide & life-threatening behavior》2015,45(5):588-599

We examined the associations between mental disorders and suicidal behavior (ideation, plans, and attempts) among new soldiers using data from the New Soldier Study (NSS) component of the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS; N = 38,507). Most new soldiers with a pre‐enlistment history of suicide attempt reported a prior mental disorder (59.0%). Each disorder examined was associated with increased odds of suicidal behavior (ORs = 2.6–8.6). Only PTSD and disorders characterized by irritability and impulsive/aggressive behavior (i.e., bipolar disorder, conduct disorder, oppositional defiant disorder, and attention‐deficit/hyperactivity disorder) predicted unplanned attempts among ideators. Mental disorders are important predictors of pre‐enlistment suicidal behavior among new soldiers and should figure prominently in suicide screening and prevention efforts.  相似文献