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91.
Kartik K. Sreenivasan Caterina Gratton Jason Vytlacil Mark D’Esposito 《Cognitive, affective & behavioral neuroscience》2014,14(1):117-128
Isolating the short-term storage component of working memory (WM) from the myriad of associated executive processes has been an enduring challenge. Recent efforts have identified patterns of activity in visual regions that contain information about items being held in WM. However, it remains unclear (1) whether these representations withstand intervening sensory input and (2) how communication between multimodal association cortex and the unimodal perceptual regions supporting WM representations is involved in WM storage. We present evidence that the features of a face held in WM are stored within face-processing regions, that these representations persist across subsequent sensory input, and that information about the match between sensory input and a memory representation is relayed forward from perceptual to prefrontal regions. Participants were presented with a series of probe faces and indicated whether each probe matched a target face held in WM. We parametrically varied the feature similarity between the probe and target faces. Activity within face-processing regions scaled linearly with the degree of feature similarity between the probe face and the features of the target face, suggesting that the features of the target face were stored in these regions. Furthermore, directed connectivity measures revealed that the direction of information flow that was optimal for performance was from sensory regions that stored the features of the target face to dorsal prefrontal regions, supporting the notion that sensory input is compared to representations stored within perceptual regions and is subsequently relayed forward. Together, these findings indicate that WM storage operations are carried out within perceptual cortex. 相似文献
92.
We examined the categorical nature of emotion word recognition. Positive, negative, and neutral words were presented in lexical decision tasks. Word frequency was additionally manipulated. In Experiment 1, “positive” and “negative” categories of words were implicitly indicated by the blocked design employed. A significant emotion–frequency interaction was obtained, replicating past research. While positive words consistently elicited faster responses than neutral words, only low frequency negative words demonstrated a similar advantage. In Experiments 2a and 2b, explicit categories (“positive,” “negative,” and “household” items) were specified to participants. Positive words again elicited faster responses than did neutral words. Responses to negative words, however, were no different than those to neutral words, regardless of their frequency. The overall pattern of effects indicates that positive words are always facilitated, frequency plays a greater role in the recognition of negative words, and a “negative” category represents a somewhat disparate set of emotions. These results support the notion that emotion word processing may be moderated by distinct systems. 相似文献
93.
Silvia?CamporesiEmail author Michael?J?McNamee 《Philosophy, ethics, and humanities in medicine : PEHM》2014,9(1):4
In light of the World Anti Doping Agency’s 2013 Code Revision process, we critically explore the applicability of two of three criteria used to determine whether a method or substance should be considered for their Prohibited List, namely its (potential) performance enhancing effects and its (potential) risk to the health of the athlete. To do so, we compare two communities of human guinea pigs: (i) individuals who make a living out of serial participation in Phase 1 pharmacology trials; and (ii) elite athletes who engage in what is effectively ‘unregulated clinical research’ by using untested prohibited or non-prohibited performance enhancing substances and methods, alone or in combination. Our comparison sheds light on norms of research ethics that these practices exacerbate with respect to the concepts of multiplicity, visibility, and consistency. We argue for the need to establish a proper governance framework to increase the accountability of these unregulated research practices in order to protect the human guinea pigs in elite sports contexts, and to establish reasonable grounds for the performance enhancing effects, and the risks to the health of the athlete, of the methods and substances that might justify their inclusion on the Prohibited List. 相似文献
94.
Emanuele Fino Sergio Melogno Paolo Iliceto Sara D’Aliesio Maria Antonietta Pinto Gabriella Candilera Ugo Sabatello 《Advances in cognitive psychology / University of Finance and Management in Warsaw》2014,10(2):32-38
Background. Adolescence represents a critical period for brain
development, addressed by neurodevelopmental models to frontal,
subcortical-limbic, and striatal activation, a pattern associated with rise of
impulsivity and deficits in inhibitory control. The present study aimed at
studying the association between self-report measures of impulsivity and
inhibitory control with executive function in adolescents, employing structural
equation modeling. Method. Tests were administered to 434 high
school students. Acting without thinking was measured through the Barratt
Impulsiveness Scale and the Dickman Impulsivity Inventory, reward sensitivity
through the Behavioral Activation System, and sensation seeking through the
Zuckerman–Kuhlman–Aluja Personali- ty Questionnaire. Inhibitory control was
assessed through the Behavioral Inhibition System. The performance at the
Wisconsin Card Sorting Task indicated executive function. Three models were
specified using Sample Covariance Matrix, and the estimated parameters using
Maximum Likelihood. Results. In the final model, impulsivity and
inhibitory control predicted executive function, but sensation seeking did not.
The fit of the model to data was excellent. Conclusions. The
hypothesis that inhibitory control and impulsivity are predictors of executive
function was supported. Our results appear informative of the validity of
self-report measures to examine the relation between impulsivity traits rather
than others to regulatory function of cognition and behavior. 相似文献
95.
96.
This study is based on exploring the trust between peers and the individual characteristics related to homophobic bullying in adolescence. Participants were 334 adolescents (141 boys and 193 girls) aged from 15 to 20 years. Participants completed the homophobic bullying scale, to investigate bullying actions towards sexual minorities, the personal attributes questionnaire, for personal characteristics, and the inventory of parent and peer attachment, to the trust between peers. The results demonstrated how female participants manifested a higher level of interpersonal traits and trust among peers than boys. Results showed how a lack of trust between peers predicts homophobic bullying. Nevertheless, we found that the lack of interpersonal characteristics represents a variable that likely mediates the relationship between lack of trust in peers and homophobic bullying. Theoretical and practical implications are discussed. 相似文献
97.
Anthony O’Hear 《Axiomathes》2018,28(6):639-651
An ideal view is sketched of the relationship between the facts established in science and the values of ethics and politics, and of the distinction between them. Some necessary qualifications are drawn, which do not essentially undermine the ideal. Then two cases of scientific work are considered in which considerations of value may in different ways be playing a more intimate role in the science than the ideal would suggest. These are Darwin’s theory of evolution and the current consensus on climate change. Are any general lessons to be drawn from these cases? 相似文献
98.
Silvia Montenegro 《Journal of Contemporary Religion》2018,33(3):509-526
ABSTRACTThe so-called ‘Triple Frontier’—the border between Paraguay, Brazil, and Argentina—is the ‘host society’ of an important Muslim community, composed mainly of Lebanese immigrants and their descendants born in Brazil and Paraguay. In less than two decades, Shi’i and Sunni Arab Muslims created mosques, religious centres, a cemetery, and three schools. Mosques, schools, and religious centres are spaces for the production of a sense of community. The institutional discourse of these entities emphasises the connection between religion and community origin, considering Islam as part of ‘Arab culture’. Taking generational differences into account, this article aims to analyse the narratives of plural identity expressed in the meanings attributed to the immigrants’ self-identification as Muslims. Based on fieldwork in the South American border area, this work aims to shed light on the way in which immigrants and their descendants reinterpret their religious belonging, informed by the new experience of living in multi-religious societies. 相似文献
99.
Frederic Gilbert Cathal D. O’Connell Tajanka Mladenovska Susan Dodds 《Science and engineering ethics》2018,24(1):73-91
Recent developments of three-dimensional printing of biomaterials (3D bioprinting) in medicine have been portrayed as demonstrating the potential to transform some medical treatments, including providing new responses to organ damage or organ failure. However, beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans, several important ethical concerns and regulatory questions need to be addressed. This article starts by raising general ethical concerns associated with the use of bioprinting in medicine, then it focuses on more particular ethical issues related to experimental testing on humans, and the lack of current international regulatory directives to guide these experiments. Accordingly, this article (1) considers whether there is a limit as to what should be bioprinted in medicine; (2) examines key risks of significant harm associated with testing 3D bioprinting for humans; (3) investigates the clinical trial paradigm used to test 3D bioprinting; (4) analyses ethical questions of irreversibility, loss of treatment opportunity and replicability; (5) explores the current lack of a specific framework for the regulation and testing of 3D bioprinting treatments. 相似文献
100.
Brenda H. O’Connell Deirdre O’Shea Stephen Gallagher 《Journal of Happiness Studies》2018,19(8):2421-2444
Despite their unprecedented popularity, the psychological mechanisms through which gratitude journals operate are poorly understood. Also the use of gratitude journaling to enhance social relationships has been neglected in past research, despite the importance of healthy relationships for people’s happiness. This randomized controlled study examined the effect of (a) a traditional gratitude journal (fostering gratitude for daily life), and (b) an interpersonal gratitude journal (fostering gratitude for one’s existing social relationships), versus (c) an active control journal, on life satisfaction. Ninety-one participants were randomized to one of three conditions with 2-week and 1-month follow-ups. The traditional gratitude intervention (vs. control) showed improvements in friendship at immediate post-test and 1-month follow-up, and these effects were accounted for by changes in gratitude over time. Additionally, the traditional gratitude intervention (vs. control) predicted enhanced life satisfaction at follow-up, and this was serially mediated by 6 week changes in gratitude and perceived friendship quality. No such differences over time were observed between the interpersonal gratitude intervention and either the control intervention or the traditional gratitude intervention. Actively appreciating things in daily life appears to be effective in enhancing the quality of people’s social relationships, and producing sustained improvements in subjective wellbeing. 相似文献